Jason Lee

In the midst of a devastating mental health crisis affecting thousands of American teens, Northeastern University psychology professor Susan Whitfield-Gabrieli says a non-invasive remedy for depression and anxiety offers hope. source https://medicalxpress.com/news/2023-03-mind-games-teen-depression-brain.html

Why are some bladder cancers resistant to a type of immunotherapy called immune checkpoint inhibitors? Penn State College of Medicine researchers have found that the genetic and pathologic diversity of cells within the tumor may be part of the challenge. source https://medicalxpress.com/news/2023-03-bladder-cancer-cells-common-genetic.html

The research team led by Professor Minseok Kim from the Department of New Biology at DGIST (President Yang Kuk) has developed a technology that can treat Charcot-Marie-Tooth (CMT) disease, an incurable hereditary disease, with electric stimulation instead of drug therapy. This technology has considerable potential for the development of an electronic medicine with minimal side effects in the future. source https://medicalxpress.com/news/2023-03-technology-charcot-marie-tooth-cmt-disease.html

The research team led by Professor Hongsoo Choi from DGIST in the Department of Robotics and Mechatronics Engineering has developed a microrobot capable of forming neural networks and sectioning hippocampal tissues in an in vitro environment in an ex vivo state. source https://medicalxpress.com/news/2023-03-microrobot-capable-neural-networks-sectioning.html

When patients request or demand an antibiotic, even when it is unlikely to help, a physician might be tempted to give in and write a prescription, especially if they're working in a busy setting like an urgent care or emergency department. source https://medicalxpress.com/news/2023-03-excess-overprescribed-antibiotics-patients-results.html

Researchers at Oregon State University have created a means of speeding up and improving the evaluation process for drugs used to combat cervical cancer. source https://medicalxpress.com/news/2023-03-quickly-potential-cervical-cancer-drugs.html

Scientists have long known that the complement cascade, a set of immune system proteins, protects against infection in the body. But in recent years, researchers have uncovered new roles for the system in the brain, including helping to whittle down connections between brain cells, or synapses, to help shape the nervous system early in life. They've also found that the pathway can become dysregulated in the adult brain, leading to cell damage and cell death seen in conditions such as Alzheimer's disease and schizophrenia. But researchers didn't know how exactly that happens. source https://medicalxpress.com/news/2023-03-reveals-driver-brain-cell-neurodegeneration.html

Researchers say the procedure could help people with sciatica avoid or delay back surgery. source https://www.webmd.com/back-pain/news/20230330/nerve-pulse-therapy-may-help-ease-sciatica?src=RSS_PUBLIC

A novel drug is showing promise for alleviating heart failure, a common condition associated with sleep apnea and a reduced lifespan. The drug, known as AF-130, was tested in an animal model at Waipapa Taumata Rau, the University of Auckland where researchers found it improved the heart's ability to pump, but, equally important, prevented sleep apnea, which itself reduces lifespan. The work is published in the journal Nature Communications. source https://medicalxpress.com/news/2023-03-drug-alleviating-heart-failure-apnea.html

High blood pressure in children is not uncommon, and research shows it may lead to high blood pressure in adulthood, as well as problems with the heart, blood vessels and kidneys, according to a new scientific statement from the American Heart Association published today in the Association's Hypertension journal. An American Heart Association scientific statement is an expert analysis of current research and may inform future guidelines. source https://medicalxpress.com/news/2023-03-children-high-blood-pressure-adults.html

Findings from an analysis of more than 66,000 abdominal hysterectomies performed in New York hospitals reveal key risk factors for surgical site infections (SSIs) following these procedures, including open surgery, obesity, diabetes, gynecological cancer, and age under 45. Published today in the American Journal of Infection Control (AJIC), the data can help inform surgical and clinical decisions to reduce post-operative infections. source https://medicalxpress.com/news/2023-03-key-factors-surgical-site-infection.html

It has been a longstanding assumption that birth mode and associated exposure of newborns to their mothers' vaginal microbiome during delivery greatly affects the development of babies' gut microbiome. source https://medicalxpress.com/news/2023-03-babies-gut-microbiome-mothers-vaginal.html

Children born to mothers who had COVID-19 during pregnancy may be more likely to develop obesity, according to a new study published online ahead of print in the Journal of Clinical Endocrinology & Metabolism. It is titled, "Accelerated Longitudinal Weight Gain Among Infants with In Utero COVID-19 Exposure." source https://medicalxpress.com/news/2023-03-covid-pregnancy-obesity-children.html

From a new study, the risk of osteoarthritis was even higher among people who had both allergic asthma and eczema. source https://www.webmd.com/arthritis/news/20230329/having-asthma-eczema-might-raise-arthritis-risk?src=RSS_PUBLIC

"Go outside and play" is the time-tested strategy for generations of parents and caregivers ready to see their little ones tuckered out by exercise. But the strategy may be losing some of its impact as more children face more hot days, according to new research from The University of Texas at Austin. A team found that, as the weather gets hotter, preschool-aged children become more sedentary. source https://medicalxpress.com/news/2023-03-temperatures-climb-preschoolers-physically.html

Imagine getting the benefits of gastric bypass surgery without going under the knife—a new class of compounds could do just that. In lab animals, these potential treatments reduce weight dramatically and lower blood glucose. The injectable compounds also avoid the side effects of nausea and vomiting that are common with current weight-loss and diabetes drugs. Now, scientists report that the new treatment not only reduces eating but also boosts calorie burn. source https://medicalxpress.com/news/2023-03-obesity-treatment-weight-loss-surgery.html

Brazil's government on Tuesday reported the 700,000th death from COVID-19 in the South American nation, which has the second most victims of the virus after the United States. source https://medicalxpress.com/news/2023-03-brazil-covid-deaths-2nd-highest.html

By analyzing tumors in unprecedented depth, the Tumor Profiler project represents an important step along the road toward personalized cancer treatments. And the team have already recorded initial successes: In a study focusing on skin cancer, tumors shrank in about one third of patients. source https://medicalxpress.com/news/2023-03-method-combat-cancer.html

A team of researchers from the U.K. and U.S. conducted the first ever investigation into how a facial transplant recipient started to accept their new appearance as part of their own identity. source https://medicalxpress.com/news/2023-03-first-of-its-kind-reveals-facial-transplant-recipient.html

Researchers with the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborators have shown that immature natural killer (NK) cells are present in patients with triple-negative breast cancer (TNBC) and likely promote, instead of inhibit, disease progression in this cancer type. source https://medicalxpress.com/news/2023-03-potential-treatment-resistance-aggressive-breast.html

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report. source https://medicalxpress.com/news/2023-03-cancer-lung-maneuvers-killer-cells.html

NRG Oncology GOG-0240 is the phase 3 randomized trial that demonstrated that the incorporation of bevacizumab with chemotherapy resulted in a statistically significant and clinically meaningful survival benefit for women with recurrent and metastatic cervical carcinoma (NCT00803062). GOG-0240 was a proof of concept in anti-angiogenesis therapy and a proof of principle in supportive care and led directly to an indication for bevacizumab in this disease in more than 60 countries. source https://medicalxpress.com/news/2023-03-molecular-drug-recurrent-metastatic-cervical.html

The burden of the pandemic has disproportionately affected socially vulnerable populations. One of the first studies to look at the intersection of social vulnerability with COVID-19 vaccine utilization and effectiveness has found that while vaccination rates have varied substantially between socially vulnerable and communities that are not socially vulnerable, there has been no difference in vaccine effectiveness between those who are socially vulnerable and those who are not. source https://medicalxpress.com/news/2023-03-socially-vulnerable-disproportionate-covid-burden.html

In the intensive care unit (ICU), critically ill patients are cared for by a multidisciplinary care team. Compassionate and caring behaviors on the part of the care team result in better outcomes for patients and their families, and care providers entering the demanding field of medicine because they wish to help people and relieve suffering. However, studies have demonstrated deficiencies in delivering compassionate health care. Evidence suggests that physicians may miss up to 90% of opportunities to respond to patients with compassion. source https://medicalxpress.com/news/2023-03-compassionate-intensive-medicine.html

Research findings from Rutgers, the University of Michigan, the University of Texas Southwestern, and the Medical University of South Carolina could save lives by enabling faster and more accurate identification of hospitalized patients who need liver transplants or are likely to recover. source https://medicalxpress.com/news/2023-03-identification-patients-liver-transplants.html

Social relationships influence physical health, but questions remain about the nature of this connection. New research in Social Psychological and Personality Science suggests that the way you feel about your close relationships may be affecting the way your body functions. source https://medicalxpress.com/news/2023-03-positive-relationships-physical-health.html

A quick, affordable diagnostic test developed by a Washington State University researcher may help curb one of the most prevalent but least discussed sexually transmitted infections. source https://medicalxpress.com/news/2023-03-finger-prick-trichomoniasis.html

Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD). A new scientific statement, published today in the American Heart Association journal Circulation: Genomic and Precision Medicine, aims to help individuals and health care professionals understand what to do when a variant is discovered. source https://medicalxpress.com/news/2023-03-genetic-unexpectedly-genes-linked-heart.html

Forgetting is not always easy. If you have ever tried to erase that annoying earworm from your mind or stop thinking about whether you locked the door after leaving the house, you know how disruptive it can be to think about something irrelevant to the task at hand. While much work in cognitive neuroscience focuses on how the human brain remembers and retains information, some cognitive neuroscientists have instead turned to forgetting—working to track exactly how we forget a piece of information and what it means for patients suffering from neurocognitive disorders. source https://medicalxpress.com/news/2023-03-purge-thoughts-mind.html

Anxiety disorder can make it hard to navigate life, but lately CBD has been touted as a natural treatment for the nerve-wracking condition. source https://medicalxpress.com/news/2023-03-cbd-anxiety.html

A group of European researchers have shown that exposure to human odors, extracted from other people's sweat, might be used to boost treatment for some mental health problems. source https://medicalxpress.com/news/2023-03-scientists-odors-people-social-anxiety.html

Scientists have found that depression and anxiety sufferers who have had a traumatic childhood tend to grow up as angry adults, and the worse the trauma, the angrier the adult. This can affect personal mental health and social interaction, but also makes it more difficult to treat the depression and anxiety. This work is presented at the European Congress of Psychiatry in Paris. source https://medicalxpress.com/news/2023-03-childhood-trauma-linked-greater-tendency.html

A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut. The findings could help identify other foods or supplements with similar nutritional benefits. source https://medicalxpress.com/news/2023-03-heart-benefits-walnuts-gut.html

All hormonal contraceptives carry a slightly increased risk of breast cancer, including the increasingly popular progestogen-only pills, according to a study published on Tuesday. source https://medicalxpress.com/news/2023-03-hormonal-contraceptives-breast-cancer.html

More than 40% of women report anxiety four months after a cardiac arrest compared with 23% of men, according to research presented today at ESC Acute CardioVascular Care 2023, a scientific congress of the European Society of Cardiology (ESC). source https://medicalxpress.com/news/2023-03-women-long-term-anxiety-cardiac-men.html

MitoQ, a mitochondrial antioxidant that is available to the public as a diet supplement, was found in a mouse study to reverse the detrimental effects that HIV and antiretroviral therapy (ART) have on mitochondria in the brain, heart, aorta, lungs, kidney and liver. source https://medicalxpress.com/news/2023-03-readily-dietary-supplement-reverse-hiv.html

Puberty can be a tough time for any kid. But it might be harder on those with central precocious puberty (CPP). source https://www.webmd.com/parenting/features/cpp-child-socially?src=RSS_PUBLIC

As the U.S. takes steps to move past the pandemic, its health care system is in a fragile financial state. At the end of 2022, about half of U.S. hospitals were in the red–making it the worst year for the industry since the start of the pandemic. No wonder, then, that hospitals are petitioning Congress for help and protesting the pending cessation of COVID funding from the federal government. source https://medicalxpress.com/news/2023-03-risky-investment-choices-covid-hospitals.html

The number of tuberculosis deaths in Europe is on the rise again after declining for almost two decades, the World Health Organization (WHO) warned on Friday. source https://medicalxpress.com/news/2023-03-tuberculosis-deaths-europe.html

Iowa Gov. Kim Reynolds has signed a pair of laws restricting the bathrooms transgender students can use and banning gender-affirming medical care amid a flood of legislation nationwide targeting the trans community. source https://medicalxpress.com/news/2023-03-iowa-governor-gender-affirming-bathroom-law.html

Researchers should focus on age, not weight, to capture the greatest number of people in all racial and ethnic groups with prediabetes and diabetes, recommends a new Northwestern Medicine study. source https://medicalxpress.com/news/2023-03-age-weight-screen-diabetes.html

Moderna's chief executive on Wednesday defended the US company's plan to quadruple the price of its lifesaving COVID vaccine to as much as $130 per dose as soon as government stockpiles run out. source https://medicalxpress.com/news/2023-03-moderna-rebuked-hike-covid-vaccine.html

Researchers at Texas A&M University have developed the first molecular therapeutic for Angelman syndrome to advance into clinical development. source https://medicalxpress.com/news/2023-03-groundbreaking-angelman-syndrome.html

More magnesium in our daily diet leads to better brain health as we age, according to scientists from the Neuroimaging and Brain Lab at The Australian National University (ANU). source https://medicalxpress.com/news/2023-03-higher-dose-magnesium-day-dementia.html

Medical sleep treatment may reduce self-harm in young people with anxiety and depression, an observational study from Karolinska Institutet in Sweden suggests. The risk of self-harm increased in the months preceding melatonin prescription and decreased thereafter, especially in girls. The study is published in the Journal of Child Psychology and Psychiatry. source https://medicalxpress.com/news/2023-03-melatonin-linked-decreased-self-harm-young.html

Low-income neighborhoods that were subject to federally sanctioned redlining beginning in the 1930s tend to host high concentrations of businesses that sell alcohol for either on- or off-premise consumption. source https://medicalxpress.com/news/2023-03-explores-association-alcohol-outlet-density.html

Laws that require physical education (PE) in elementary schools are not curbing the obesity epidemic, according to a new study from public policy researchers at The University of Texas at Austin and the University of Iowa. source https://medicalxpress.com/news/2023-03-physical-policies-schools-curbed-childhood.html

Under the Risk Evaluation and Mitigation Strategy (REMS), prenatal exposure to phentermine-topiramate is lower than topiramate and other antiobesity medications (AOMs), according to a study published online March 21 in the Annals of Internal Medicine. source https://medicalxpress.com/news/2023-03-prenatal-exposure-phentermine-topiramate-safety.html

French scientist Etienne-Emile Baulieu, known as the father of the abortion pill, said it was "scandalous" and "a setback for women's freedom" that the US state of Wyoming has banned the drug. source https://medicalxpress.com/news/2023-03-french-inventor-abortion-pill-wyoming.html

Dysregulation of microRNAs, which are molecules involved in controlling gene expression, can promote tumor formation and progression. A study in The FASEB Journal found that the miR-145 microRNA can suppress the growth of cervical cancer cells. source https://medicalxpress.com/news/2023-03-boosting-effects-microrna-benefit-patients.html

Nine in ten women in England enter pregnancy with at least one indicator that may increase health risks to them and their baby, according to new research. source https://medicalxpress.com/news/2023-03-women-england-pregnancy-indicator-baby.html

Statins are the most commonly used medication in lowering blood cholesterol, prescribed to tens of millions in the Western world. Statins act through inhibition of the enzyme HMG CoA reductase. Nearly 20% of statin users develop muscle symptoms ("statin myopathy") including weakness and pain. In about 1%, this myopathy is severe and does not subside months after cessation of statin treatment. source https://medicalxpress.com/news/2023-03-drug-effective-treatment-rare-hereditary.html

Many people use dry shampoo in their normal routine, stretching the days between washing their hair in the shower. In October of last year, the Food and Drug Administration found potentially elevated levels of benzene, a carcinogen, or cancer-causing chemical, in these products. Popular brands of dry shampoo are under a voluntary recall of products manufactured before October 2021 because they contained benzene. source https://medicalxpress.com/news/2023-03-dry-shampoo-cancer.html

Young children with autism spectrum disorder (ASD) are much less likely to receive vision screening than their peers, despite high risk for serious eye disorders, according to a study by Nemours Children's Health published today in Pediatrics. source https://medicalxpress.com/news/2023-03-children-autism-vision-screening-high.html

New research shows that the built environment, not social and economic environments, is a strong predictor of adolescents' body mass index (BMI), overweight and obesity status, and eating behaviors, according to a new study in Obesity. This study provides the first quasi-experimental empirical evidence of these environments on adolescents' BMI, overweight, obesity and related behaviors. source https://medicalxpress.com/news/2023-03-built-environment-strongest-predictor-adolescent.html

Society and social interaction play a key role in life for humans. The well-being of a person greatly depends upon their ability to be part of complex sociocultural institutions. Even during infancy, humans rely on their social interactions with other humans for social and cultural learning, subsequent adaptation to different social environments, and ultimately, survival. source https://medicalxpress.com/news/2023-03-infants-behavior-social-interactions.html

A study from the Department of Defense found that military air and ground crew have an increased rates of cancer when compared to the general population, but they were not more likely to die from cancer. source https://www.webmd.com/cancer/news/20230320/military-pilots-ground-crew-at-higher-risk-of-cancer?src=RSS_PUBLIC

Researchers at Stanford University in California have devised a fluorescence-activated cell-sorting method for isolating distinct neural stem and progenitor cell types from human brain tissue. The markers used in the study are conserved across diverse brain regions. The technique should aid future research on neurodevelopment and accelerate the development of neuronal cell-transplantation-based therapeutic regimens to treat a host of neurological disorders. source https://medicalxpress.com/news/2023-03-method-function-neural-stem-cells.html

Certain personality traits are associated with satisfaction in life, and despite the changes people may experience in social roles and responsibilities over the course of their adult lives, that association is stable regardless of age, according to research published by the American Psychological Association in the Journal of Personality and Social Psychology. source https://medicalxpress.com/news/2023-03-personality-traits-satisfaction-linked-adult.html

Most people who ranked high in "joy of missing out" or JOMO also reported high levels of social anxiety in a recent Washington State University-led study. source https://medicalxpress.com/news/2023-03-people-real-joy-jomo.html

Gestational diabetes has been reported to be on the rise, but a new study from British Columbia found that changes in screening practices explain much of the increase. The study is published in CMAJ (Canadian Medical Association Journal). source https://medicalxpress.com/news/2023-03-gestational-diabetes-linked-largely-screening.html

How the field of legal epidemiology uses rigorous scientific methods to investigate the link between policy and public health. source https://www.webmd.com/a-to-z-guides/features/legal-epidemiology?src=RSS_PUBLIC

A cancer-causing chemical that is widely used to degrease aviation components and heavy machinery could also be linked to Parkinson's disease, according to a new research paper that recommends increased scrutiny of areas long contaminated by the compound. source https://medicalxpress.com/news/2023-03-common-industrial-chemical-fueling-parkinson.html

A symposium aiming to provide a better understanding of the tumor microenvironment, immune tolerogenic niches at cancer initiation, and novel immunotherapeutic strategies in head and neck cancer patients was featured at the 52nd Annual Meeting & Exhibition of the AADOCR, held in conjunction with the 47th Annual Meeting of the CADR. The AADOCR/CADR Annual Meeting & Exhibition took place at the Oregon Convention Center in Portland on March 15-18, 2023. source https://medicalxpress.com/news/2023-03-immunotherapy-strategies-complexity-tumor-microenvironment.html

Healthy dogs and cats could be passing on multidrug-resistant organisms (MDROs; bacteria that resist treatment with more than one antibiotic) to their hospitalized owners, and likewise humans could be transmitting these dangerous microbes to their pets, according to new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April). source https://medicalxpress.com/news/2023-03-multi-drug-resistant-transmitted-healthy-dogs.html

A study in the Journal of The National Cancer Institute Cancer Spectrum looked at chatbots and artificial intelligence (AI), as they become popular resources for cancer information. They found these resources give accurate information when asked about common cancer myths and misconceptions. In the first study of its kind, Skyler Johnson, MD, physician-scientist at Huntsman Cancer Institute and assistant professor in the department of radiation oncology at the University of Utah (the U), evaluated the reliability and accuracy of ChatGPT's cancer information. source https://medicalxpress.com/news/2023-03-cancer-chatgpt.html

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans. The study, to be published March 17 in the Journal of Experimental Medicine, uses a new, highly versatile form of CRISPR-based genome editing with the potential to correct a wide variety of disease-causing genetic mutations. source https://medicalxpress.com/news/2023-03-gene-editing-technique-reverses-vision-loss.html

While COVID-19 can be transmitted via contact with contaminated objects, most studies have focused on airborne droplet transmission. Against this backdrop, scientists from Japan conducted detailed computational simulations based on real-life behavioral data to visualize how viruses spread to common household items shortly after people return home. Their results illustrate the importance of immediate hand sanitization upon returning to avoid contact infection, reinforcing the effectiveness of a good hygiene. source https://medicalxpress.com/news/2023-03-dangerous-hitchhikers-visualizing-covid-homes.html

Is a dog more similar to a chicken or an eagle? Is a penguin noisy? Is a whale friendly? source https://medicalxpress.com/news/2023-03-dog-chicken-explores.html

Increasingly dense cell clusters in growing tumors convert blood vessels into fiber-filled channels. This makes immune cells less effective, as findings by researchers from ETH Zurich and the University of Strasbourg suggest. Their research is published in Matrix Biology. source https://medicalxpress.com/news/2023-03-tumors-blood-vessels.html

A study aiming to identify high prescribers by defining trajectories of opioid prescribing among dentists and oral and maxillofacial surgeons (OMFS) was presented at the 52nd Annual Meeting & Exhibition of the AADOCR, held in conjunction with the 47th Annual Meeting of the CADR. The AADOCR/CADR Annual Meeting & Exhibition took place at the Oregon Convention Center in Portland on March 15-18, 2023. source https://medicalxpress.com/news/2023-03-trajectories-opioid-dentists-omfs-high.html

A study evaluating opioid prescribing patterns and postoperative complications in patients undergoing third molar removal treated with and without liposomal bupivacaine was presented at the 52nd Annual Meeting & Exhibition of the AADOCR, held in conjunction with the 47th Annual Meeting of the CADR. The AADOCR/CADR Annual Meeting & Exhibition took place at the Oregon Convention Center in Portland on March 15-18, 2023. source https://medicalxpress.com/news/2023-03-explores-opioid-patterns-complications-liposomal.html

About 17% of women with unexplained infertility also have gene variants known to cause disease, from common conditions like heart disease to rare problems like ALS, Medical College of Georgia researchers report. source https://medicalxpress.com/news/2023-03-disproportionate-percentage-females-unexplained-infertility.html

B lymphocytes—also known simply as B cells—play a central role in the immune system. If pathogens enter the body, B cells are activated and develop into plasma cells, which then release antibodies. One important step in this process is the germinal center reaction. If the B cells' maturation into plasma cells is disrupted, multiple myeloma can develop—one of the most common blood cancers. This disease has a variety of subtypes and is not yet curable. source https://medicalxpress.com/news/2023-03-team-successfully-generates-mouse-subtypes.html

A UBC student researcher is looking at how the lack of health care resources for pregnant women living in the Northwest Territories influences their delivery and overall wellbeing. source https://medicalxpress.com/news/2023-03-indigenous-women-outsized-hardships-birth.html

A small nucleus in the brainstem called locus coeruleus (literally the "blue spot,") is the primary source of a major neuromodulator, norepinephrine (NE), an important mediator of the 'fight or flight' response in animals. However, very little is known about the local connections of this small albeit critically important group of neurons. A recent pioneering study published in eLife from the laboratory of Dr. Xiaolong Jiang, investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and assistant professor at Baylor College of Medicine, now reveals the cellular composition and circuit organization of the locus coeruleus in adult mice. source https://medicalxpress.com/news/2023-03-comprehensive-circuit-reveals-unexpected-facts.html

Findings from a new study published in the American Journal of Infection Control highlight perceptions of and barriers to reliable hand hygiene among specific clinician subgroups. The results, from the first study of its kind, provide insights that can be used to design and implement future targeted interventions to optimize hand hygiene reliability among medical professionals. source https://medicalxpress.com/news/2023-03-highlight-clinician-perspectives-barriers-reliable.html

Almost 3 million unintended pregnancies happen each year in the United States. Read here to find out about emergency contraception. source https://www.webmd.com/sex/birth-control/features/emergency-contraception?src=RSS_PUBLIC

Trust in information given out by the government on cancer fell sharply among the Black population—by almost half—during the COVID-19 pandemic, findings of a national U.S. study have shown. source https://medicalxpress.com/news/2023-03-cancer-declined-black-americans-pandemic.html

Anna Durbin was in Brazil in December 2015 when the Zika virus erupted in the country's northeast. Although she'd flown to São Paulo to work on a dengue vaccine, Durbin returned to Baltimore preoccupied with Zika. source https://medicalxpress.com/news/2023-03-human-trials-vaccine.html

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases. source https://medicalxpress.com/news/2023-03-common-metabolite-autoimmune-diseases.html

According to a new study published by Mayo Clinic researchers, the COVID-19 pandemic was linked to a 17% increase in the death rate in Minnesota during the first year of the pandemic compared to the two previous years. source https://medicalxpress.com/news/2023-03-deaths-despair-contribute-minnesota-death.html

The doctor who exposed China's cover-up of the SARS epidemic in 2003 has died aged 91, his family confirmed on Wednesday. source https://medicalxpress.com/news/2023-03-doctor-exposed-china-sars-cover-up.html

His medical studies in Syria keep Mohammed Shasho busy enough but whenever he can he also pores over German vocabulary and grammar points in hopes of a move to Europe. source https://medicalxpress.com/news/2023-03-syrian-medical-students-german.html

US abortion opponents are hoping for a national ban on a widely used abortion pill when their lawsuit against government drug regulators is argued Wednesday in the Texas court of a deeply conservative judge believed to be sympathetic to their cause. source https://medicalxpress.com/news/2023-03-abortion-pill-threat-texas-court.html

Immunotherapy is an effective form of therapy for different types of cancer. However, for pancreatic cancer, its effect is limited and differs between men and women. Researchers at Karolinska Institutet have now found a possible explanation for this sex difference. source https://medicalxpress.com/news/2023-03-immune-cell-explanation-sex-differences.html

The reclassification of two prescription drugs as class C controlled substances, following concerns about people misusing and becoming addicted to them, had a "limited" immediate impact according to a new study. source https://medicalxpress.com/news/2023-03-prescription-drug-reclassification-limited-impact.html

Scientists have discovered why breast cancer cells that have spread to the lungs may "wake up" following years of sleep, forming incurable secondary tumors. source https://medicalxpress.com/news/2023-03-scientists-secondary-breast-cancer.html

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures. But researchers at Boston Children's Hospital and Harvard Medical School are looking for new pathways for slowing neuronal dysfunction and treating amyotrophic lateral sclerosis (ALS), a fatal motor neuron disease. The team found that proteins involved in the innate immune system could be at the root of the disease. source https://medicalxpress.com/news/2023-03-immune-pathway-amyotrophic-lateral-sclerosis.html

US pharmaceutical giant Pfizer announced Monday that it had reached a deal to buy biotech firm Seagen, specializing in innovative cancer treatment, for $43 billion. source https://medicalxpress.com/news/2023-03-pfizer-buys-biotech-firm-seagen.html

Tens of thousands of junior doctors went on strike across England on Monday to demand better pay, kicking off three days of widespread disruption at the U.K.'s state-funded hospitals and health clinics. source https://medicalxpress.com/news/2023-03-uk-tens-thousands-doctors-day.html

Modifiable risk and protective factors (e.g., engaging in active lifestyles and avoiding alcohol or smoking, amongst others) are key agents for dementia prevention, and they also exert an important effect on cognitive trajectories of non-demented older adults. In a new editorial published in the journal Aging, researchers David Bartrés-Faz, Cristina Solé-Padullés and Natalie L. Marchant from the University of Barcelona discuss recent research that has begun to identify psychological processes that confer relative risk and protection. source https://medicalxpress.com/news/2023-03-incorporating-psychological-treatment-dementia.html

A large LSTM-led trial confirms new antimalarial, dihydroartemisinin-piperaquine, is more effective at preventing malaria than current WHO recommended treatment but does not improve adverse birth outcomes. source https://medicalxpress.com/news/2023-03-antimalarial-effective-current-treatment-adverse.html

A scientific definition to determine whether a man's erection can be deemed a "grower " or a "shower" has been produced by researchers. source https://medicalxpress.com/news/2023-03-difference-growers-showers-revealed.html

Vasectomies are much less likely to cause complications than expected, according to a new UK study reviewing the outcomes from over 90,000 vasectomies performed over 15 years. source https://medicalxpress.com/news/2023-03-uk-vasectomies-safer.html

Surgeons in Germany have shown a small technical change to keyhole surgery for prostate cancer can more than halve one of the most common post-operative complications—where lymphatic fluid collects in the pelvis. source https://medicalxpress.com/news/2023-03-technique-postoperative-complications-prostate-cancer.html

Researchers have found long-term evidence that actively monitoring localized prostate cancer is a safe alternative to immediate surgery or radiation. source https://medicalxpress.com/news/2023-03-prostate-cancer-treatment-men.html

Three years since the Covid pandemic began, nearly 200 prominent world figures called on Saturday for the vaccine inequity seen during the crisis to be relegated to history. source https://medicalxpress.com/news/2023-03-leaders-vaccine-inequity.html

Existing thought in the orthopedic world is that treating a bunion with the minimally invasive procedure MISB may make a person's flatfoot worse. A new study by researchers at Hospital for Special Surgery (HSS) in New York City shows that this procedure does not make flatfoot worse in people with asymptomatic flatfoot and may even improve the condition. The findings were presented today at the annual meeting of the American Academy of Orthopaedic Surgeons (AAOS). source https://medicalxpress.com/news/2023-03-misb-minimally-invasive-procedure-bunions.html

On March 11, 2020, when the World Health Organization declared COVID-19 a pandemic, everyone wanted to know: "What is this disease, and how can we stop it?" source https://medicalxpress.com/news/2023-03-years-covid-world-reshaped-pandemic.html

How to self-advocate when you have advanced breast cancer, including tips for talking to your doctor and educating yourself. source https://www.webmd.com/breast-cancer/features/metastatic-bc-advocate-yourself?src=RSS_PUBLIC

Although autism is a common neurodevelopmental disorder, the multiple factors behind its onset are still not fully understood. Animal models of idiopathic autism, especially mice, are often used to help researchers understand the complicated mechanisms behind the disorder, with BTBR/J being the most commonly used mouse model in the world. source https://medicalxpress.com/news/2023-03-ancient-virus-genome-autism.html

The tissue area that surrounds our teeth is known as the gingiva, and healthy teeth will nestle firmly into the gums thanks to the many gingival fibers that connect the tooth to the gingiva. The gingiva is home to fibroblasts—cells that contribute to the formation of connective tissue. A group of scientists from Tohoku University have discovered that gingiva stiffness influences the properties of gingival fibroblasts, which in turn affects whether inflammation is likely to occur and make gingival fibers difficult to form. source https://medicalxpress.com/news/2023-03-reveals-soft-gums-prone-inflammation.html

Pregnant persons should dim the lights in their home and turn off or at least dim their screens (computer monitors and smartphones) a few hours before bedtime to reduce the risk of gestational diabetes mellitus, a new Northwestern Medicine study shows. source https://medicalxpress.com/news/2023-03-dim-bedtime-gestational-diabetes.html

After years of refusing to expand Medicaid benefits for new moms, Republican officials in more than a half-dozen states are now reversing course and trumpeting that coverage as central to their conservative, anti-abortion agenda. source https://medicalxpress.com/news/2023-03-medicaid-coverage-moms-gaining-gop.html

During the first year of the pandemic, states in the U.S. with high rates of death from COVID-19 saw significant increases in other causes of death, too, including cardiovascular disease, dementia, diabetes, and influenza. That's according to findings from the University of Pennsylvania, Boston University, and the Robert Wood Johnson Foundation published recently in the journal PLOS ONE. source https://medicalxpress.com/news/2023-03-states-high-covid-death-mortality.html

What helps when you can't sleep? WebMD's survey offers some tips for how to sleep better with insomnia. source https://www.webmd.com/sleep-disorders/features/tips-better-sleep?src=RSS_PUBLIC

What are the most common causes of sleep problems? A WebMD study looks at how well Americans sleep and what's keeping us awake. source https://www.webmd.com/sleep-disorders/features/sleep-quality-survey?src=RSS_PUBLIC

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections. Researchers have now discovered that a new class of oral drugs that acts directly on human cells can inhibit a diverse range of pathogenic SARS-CoV-2 strains. source https://medicalxpress.com/news/2023-03-class-drugs-resistant-covid-variants.html

According to an accepted manuscript published in ARRS' American Journal of Roentgenology (AJR), axillary lymphadenopathy after a COVID-19 vaccine booster dose has a mean time to resolution of 102 days, shorter than the time to resolution after the initial series. source https://medicalxpress.com/news/2023-03-axillary-lymphadenopathy-covid-vaccine-boostertime.html

Research published today in Clinical and Experimental Immunology shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver). source https://medicalxpress.com/news/2023-03-naturally-peptide-tackle-root-obesity-related.html

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS), co-led by Professor Daniel G. Tenen and Associate Professor Polly Chen Leilei, made an unprecedented discovery of a hitherto unappreciated mechanism leading to ADAR2 (adenosine deaminases acting on RNA) dysregulation in core binding factor acute myelogenous leukemias (CBF-AML), and highlighted the functional relevance of the role of ADAR2 role in leukemogenesis. The research was published in the journal Blood on Feb. 16, 2023. source https://medicalxpress.com/news/2023-03-role-rna-adar2-core-factor.html

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham health care system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody. Investigators found evidence that the drug dampened the inflammatory T cell response and decreased lung inflammation in patients with COVID-19. Further analysis showed the same gene expression modulation in patients with multiple sclerosis, who experienced decreased brain inflammation, suggesting that Foralumab could be used to treat other diseases. Their results are published in the Proceedings of the National Academy of Sciences. source https://medicalxpress.com/news/2023-03-nasal-monoclonal-antibody-treatment-covid-.html

The nitrate ingested over the course of a person's adult lifetime through the consumption of tap water and bottled water could be a risk factor for prostate cancer, particularly in the case of aggressive tumors and in younger men. This is the conclusion of a study conducted in Spain and led by the Barcelona Institute for Global Health (ISGlobal). The findings have been published in Environmental Health Perspectives. source https://medicalxpress.com/news/2023-03-long-term-exposure-nitrates-factor-prostate.html

People recently released from prison in Oregon face a risk for opioid overdose 10 times greater than the general public, according to a new study led by an Oregon State University College of Pharmacy scientist. source https://medicalxpress.com/news/2023-03-opioid-overdose-greater-prison.html

Cameras that can scan an entire body in a fraction of a second can give spinal surgeons an accurate assessment of how much range of motion youth with scoliosis have in their torso—a critical piece of information for guiding management of people with the condition, researchers at Hospital for Special Surgery (HSS) in New York City have found. source https://medicalxpress.com/news/2023-03-3d-surface-topographic-scans-yield.html

Researchers from Children's Hospital of Philadelphia (CHOP) have found that opioids were responsible for more than half of all fatal poisonings in children ages 5 and younger between 2005 and 2018, more than double the proportion of fatal poisonings caused by opioids in 2005. Additionally, over-the-counter drugs still contribute to fatal poisonings in this age group despite increased regulation. The findings, published today in the journal Pediatrics, underscore the need for improved intervention to prevent further fatal poisonings. source https://medicalxpress.com/news/2023-03-fatal-opioid-poisonings-children-year.html

In an analysis of more than 415,00 electronic health records of healthy, full-term births in Southern California, a team of researchers led by the University of California, Irvine, determined that exposure to green space and tree coverage was associated with a decreased risk of postpartum depression among mothers. source https://medicalxpress.com/news/2023-03-exposure-green-space-linked-postpartum.html