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Showing posts from October, 2022

Do water bottles expire? What you need to know when the power goes out

Flashlights and candles aren't the only things people should have on hand during natural disasters and storms. source https://medicalxpress.com/news/2022-10-bottles-expire-power.html

Newly designed molecule could help treat deadly lung condition

Idiopathic pulmonary fibrosis (IPF) is a deadly condition. The only available therapies can slow disease progression, but they are not a cure and often cause intolerable side effects. Patients diagnosed with the disease will die within three to five years of diagnosis. "It is more lethal than most cancers," says Naftali Kaminski, MD, Boehringer Ingelheim Pharmaceuticals, Inc. Endowed Professor of Medicine (Pulmonary) at Yale School of Medicine. source https://medicalxpress.com/news/2022-10-newly-molecule-deadly-lung-condition.html

Study finds dieters may overestimate the healthiness of their eating habits

In a small study, most adults seeking to lose weight overestimated the healthiness of their diet, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2022. The meeting, held in person in Chicago and virtually, Nov. 5-7, 2022, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science. source https://medicalxpress.com/news/2022-10-dieters-overestimate-healthiness-habits.html

Smartphone alerts may lead to faster response to in-hospital cardiac arrest, 'code blue'

Sixty seconds can make or break the outcome of a hospital "code blue" or cardiac arrest response. New research found a hospital code response team rushing to a patient in cardiac arrest may arrive at least one minute quicker and may also lead to better patient outcomes with the use of a smartphone emergency code notification system that activates the team through text messages. The findings are preliminary research to be presented at the American Heart Association's Resuscitation Science Symposium 2022. The 2022 meeting will be held in person in Chicago, November 5-6, 2022, and will feature the most recent advances related to treating cardiopulmonary arrest and life-threatening traumatic injury. source https://medicalxpress.com/news/2022-10-smartphone-faster-response-in-hospital-cardiac.html

Researcher combines AI and microelectronics to create neural implants that fight brain disorders

Neural implants can help treat brain disorders such as Parkinson's disease and epilepsy by directly modulating abnormal activities—and the University of Toronto's Xilin Liu is working with microelectronics and artificial intelligence to make this emerging technology both safer and smarter. source https://medicalxpress.com/news/2022-10-combines-ai-microelectronics-neural-implants.html

Vitiligo: Treatment Options and Innovations

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Vitiligo causes white patches on your skin that can affect your quality of life and even be emotionally devastating. Treatments include tried-and-true steroid creams, new immune-suppressing drugs, light therapy, and cell transplant surgery. source https://www.webmd.com/skin-problems-and-treatments/features/future-treating-vitiligo?src=RSS_PUBLIC

Video games could improve kids' brains: study

Parents often worry about the harmful impacts of video games on their children, from mental health and social problems to missing out on exercise. source https://medicalxpress.com/news/2022-10-video-games-kids-brains.html

Cholera overwhelms Haiti as cases, deaths spike amid crisis

The sun shone down on Stanley Joliva as medical staff at an open-air clinic hovered around him, pumping air into his lungs and giving him chest compressions until he died. source https://medicalxpress.com/news/2022-10-cholera-overwhelms-haiti-cases-deaths.html

Study reveals sharp rise in stroke cases among young adults in Oxfordshire

New research has shown a sharp increase in the incidence of stroke in young adults, in a study of more than 94,000 people in Oxfordshire. source https://medicalxpress.com/news/2022-10-reveals-sharp-cases-young-adults.html

New pan-coronavirus vaccine passes key experiments, demonstrates protection

In laboratory and primate tests, a new pan-coronavirus vaccine developed by the Duke Human Vaccine Institute (DHVI) has demonstrated wide protection against SARS-CoV-2 viruses and variants, including omicron BA.5. source https://medicalxpress.com/news/2022-10-pan-coronavirus-vaccine-key.html

Pleasure-producing human clitoris has more than 10,000 nerve fibers

More than 10,000 nerve fibers enable the pleasurable sensations created by the human clitoris, according to new Oregon Health & Science University-led research presented at a joint scientific meeting of the Sexual Medicine Society of North America and the International Society for Sexual Medicine. source https://medicalxpress.com/news/2022-10-pleasure-producing-human-clitoris-nerve-fibers.html

Researchers reveal why shingles can lead to stroke

Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research from the University of Colorado Anschutz Medical Campus. source https://medicalxpress.com/news/2022-10-reveal-shingles.html

Large stroke trial finds intensive blood pressure lowering after clot removal worsens recovery

A large stroke trial has shown that intensive blood pressure lowering after clot removal worsens recovery. The results of the trial, stopped early due to the significance of the findings, were presented in a late-breaking session at the World Stroke Congress and simultaneously published in The Lancet. source https://medicalxpress.com/news/2022-10-large-trial-intensive-blood-pressure.html

Black patients with atrial fibrillation more likely to experience adverse outcomes

Black patients with atrial fibrillation are less likely to be prescribed newer anticoagulant medications when they leave the hospital compared to their white counterparts and are consequently more likely to experience adverse outcomes, including stroke and death, according to a new study led by University of Pittsburgh School of Medicine physician-scientists and published today in JAMA Cardiology. source https://medicalxpress.com/news/2022-10-black-patients-atrial-fibrillation-adverse.html

Study reveals pathways for aggressive prostate cancer subtype

Cribriform prostate cancer is an aggressive subtype of the disease characterized by its histology, but little is known about its molecular pathways. Research from Vanderbilt-Ingram Cancer Center has revealed new information about these pathways, including potential therapies. source https://medicalxpress.com/news/2022-10-reveals-pathways-aggressive-prostate-cancer.html

African health official: Ebola in Uganda is under control

Uganda's Ebola outbreak is under control, a top public health official in Africa said Thursday, noting that local health authorities are doing well to trace most contacts. source https://medicalxpress.com/news/2022-10-african-health-ebola-uganda.html

Feeling chirpy: Being around birds is linked to lasting mental health benefits

New research from King's College London has found that seeing or hearing birds is associated with an improvement in mental well-being that can last up to eight hours. source https://medicalxpress.com/news/2022-10-chirpy-birds-linked-mental-health.html

Researchers take key step toward improving treatment of cystic fibrosis

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy. source https://medicalxpress.com/news/2022-10-key-treatment-cystic-fibrosis.html

Can gut bacteria cause rheumatoid arthritis?

Researchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut could be responsible for triggering rheumatoid arthritis (RA) in people already at risk for the autoimmune disease. source https://medicalxpress.com/news/2022-10-gut-bacteria-rheumatoid-arthritis.html

Researchers study changes in the health of Scottish veterans over time

A major study has examined changes in the health of Scottish veterans over time compared with people who have never served, concluding that despite many health outcomes for veterans improving, some important challenges remain. The researchers found that the Defense Health Strategy, implemented from the late 1970s, which introduced mandatory fitness training and health promotion in the Armed Forces, as well the ban on indoor smoking, have been key components in improving the health outcomes for veterans. source https://medicalxpress.com/news/2022-10-health-scottish-veterans.html

Which Atopic Dermatitis Treatments Work Best?

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What’s the best treatment for atopic dermatitis? What if it’s mild AD? What if it’s severe AD? What’s most effective? How long can I use medication for AD? Learn about different treatments for atopic dermatitis, which treatments are most effective, and how to use them. source https://www.webmd.com/skin-problems-and-treatments/eczema/features/atopicd-skin-treatments?src=RSS_PUBLIC

Researchers identify cells in the blood vessels of the brain involved in producing a fever

Researchers at Linköping University have identified in mice the cells in the blood vessels of the brain that are necessary for a fever reaction. The results have been published in Proceedings of the National Academy of Sciences (PNAS), and answer a long-standing question of which organs are involved in producing fever. source https://medicalxpress.com/news/2022-10-cells-blood-vessels-brain-involved.html

Germany unveils cannabis liberalization plan, with caveats

Germany's health minister unveiled a plan Wednesday to decriminalize the possession of up to 30 grams (about 1 ounce) of cannabis and to allow the sale of the substance to adults for recreational purposes in a controlled market. source https://medicalxpress.com/news/2022-10-germany-unveils-cannabis-liberalization-caveats.html

China launches a COVID-19 vaccine inhaled through the mouth

The Chinese city of Shanghai started administering an inhalable COVID-19 vaccine on Wednesday in what appears to be a world first. source https://medicalxpress.com/news/2022-10-china-covid-vaccine-inhaled-mouth.html

Autistic people are more likely to experience depression and anxiety during pregnancy

Autistic people are more vulnerable to depression and anxiety during pregnancy, according to new research from the University of Cambridge. The results are published in the Journal of Autism and Developmental Disorders and have important implications for supporting autistic people during pregnancy. source https://medicalxpress.com/news/2022-10-autistic-people-depression-anxiety-pregnancy.html

What’s Behind “Lockdown Nostalgia”?

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With coronavirus stubbornly lingering, pandemic fatigue has fueled widespread longing for the perceived simplicities, innocence, and sense of togetherness of the early days of COVID-19. source https://www.webmd.com/lung/features/pandemic-nostalgia?src=RSS_PUBLIC

Psychedelics paired with therapy could treat chronic mental health conditions

Psychedelic drugs are mostly banned in Europe, but new research suggests they may be beneficial to some when taken in a controlled setting. source https://medicalxpress.com/news/2022-10-psychedelics-paired-therapy-chronic-mental.html

Sticky cell fingers help keep breast tumors contained

Researchers at Turku University and Åbo Akademi University, Finland, have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumors. source https://medicalxpress.com/news/2022-10-sticky-cell-fingers-breast-tumors.html

Lack of access to healthy food may raise risk of death from heart failure

A study reviewing data from nearly 3,000 counties in the United States has found that living in a community with easy access to grocery stores and affordable, healthy food is associated with lower heart failure death rates, according to new research published today in Circulation: Heart Failure. source https://medicalxpress.com/news/2022-10-lack-access-healthy-food-death.html

Physicians call on health care organizations to reduce greenhouse gas emissions

In a new commentary published in Annals of Internal Medicine, authors from Lahey Hospital and Medical Center, Beth Israel Lahey Health, Tufts University of School of Medicine and Case Western Reserve University offer strategies for healthcare organizations to reduce greenhouse gas emissions and outline potential strategy tradeoffs to consider toward this goal. They say health care has a moral imperative to reduce its emissions and environmental footprint and force transformation across all other sectors it touches. source https://medicalxpress.com/news/2022-10-physicians-health-greenhouse-gas-emissions.html

Vitamin D deficiency associated with increased mortality risk

A study of more than 300,000 adults in the United Kingdom has found support for a causal relationship between vitamin D deficiency and mortality. These findings suggest a need for public health strategies to maintain healthy levels of vitamin D in the population. The study is published in Annals of Internal Medicine. source https://medicalxpress.com/news/2022-10-vitamin-d-deficiency-mortality.html

What's behind worrying RSV surge in US children's hospitals?

Children's hospitals in parts of the U.S. are seeing a surge in a common respiratory illness that can cause severe breathing problems for babies. source https://medicalxpress.com/news/2022-10-rsv-surge-children-hospitals.html

Common, usually harmless group of bacteria associated with higher death rates in kidney patients

A big group of bacteria found in our soil, our water and our showerheads are harmless for most of us, but a new study indicates they are associated with an increased risk of dying in individuals whose kidneys have failed. source https://medicalxpress.com/news/2022-10-common-harmless-group-bacteria-higher.html

Revealed: Anterior prefrontal-putamen circuit essential to response inhibition in humans

The prefrontal-subthalamic neural circuit within the human brain is responsible for stopping inappropriate responses. The striatum in the brain is the main route of direct or excitatory and indirect or inhibitory signals, and this indirect pathway is thought to serve as an alternative stopping mechanism in humans. However, we do not have a clear understanding of how stopping is managed by the prefrontal-striatal indirect pathway. source https://medicalxpress.com/news/2022-10-revealed-anterior-prefrontal-putamen-circuit-essential.html

Next generation sunscreen to better prevent harmful effects of UV solar radiation

New formulation sunscreens could offer better protect against skin cancer by filtering out more harmful ultra-violet rays. source https://medicalxpress.com/news/2022-10-sunscreen-effects-uv-solar.html

Viral shedding ebbs over time with HSV-1 genital infections

People with a genital infection of the herpes simplex virus type 1 (HSV-1), which usually causes cold sores, frequently shed the virus in the first months after infection, raising the risk that they might spread the virus to sexual partners during this time. source https://medicalxpress.com/news/2022-10-viral-ebbs-hsv-genital-infections.html

Concerns over COVID vaccine's effectiveness, not general medical mistrust, slowed early uptake in Black, Latinx

When the COVID-19 vaccine became widely available in spring of 2021, Black and Latinx populations had a slower uptake of the vaccine. While this gap has narrowed over time, new research from DePaul University examines why people in communities of color delayed their vaccinations. The findings may inform more persuasive messages to break down vaccine hesitancy around the COVID-19 booster, flu shot and future vaccines, said lead researcher Joanna Buscemi. source https://medicalxpress.com/news/2022-10-covid-vaccine-effectiveness-medical-mistrust.html

Poor professional development may explain failure of push to promote physical health in schools

International efforts to promote children's physical health in schools are failing because of ineffective teacher professional development, new research suggests. source https://medicalxpress.com/news/2022-10-poor-professional-failure-physical-health.html

Green eyeglasses reduce pain-related anxiety in fibromyalgia patients, study shows

Wearing special green eyeglasses for several hours a day reduces pain-related anxiety and may help decrease the need for opioids to manage severe pain in fibromyalgia patients and possibly others who experience chronic pain, according to a study being presented at the Anesthesiology 2022 annual meeting. source https://medicalxpress.com/news/2022-10-green-eyeglasses-pain-related-anxiety-fibromyalgia.html

Women, minorities, patients on Medicaid less likely to receive regional anesthesia, study shows

Women, minorities and patients enrolled in Medicaid are less likely to receive regional anesthesia techniques that consistently improve outcomes after surgery, suggests research being presented at the Anesthesiology 2022 annual meeting. source https://medicalxpress.com/news/2022-10-women-minorities-patients-medicaid-regional.html

Binge eating is more common than anorexia or bulimia—but it remains a hidden and hard-to-treat disorder

For many people, the term "eating disorder" will bring to mind its two most familiar forms—anorexia nervosa and bulimia nervosa. What they may not realise, however, is that "binge eating disorder" is more common than the other two combined and can significantly reduce quality of life. source https://medicalxpress.com/news/2022-10-binge-common-anorexia-bulimiabut-hidden.html

Life expectancy improves in some countries after big drops in 2020, but US and others see further falls

The COVID pandemic triggered an unprecedented rise in deaths around the world, leading to falls in life expectancy. In research last year, we found that 2020 saw significant life expectancy losses, including more than two years in the U.S. and one year in England and Wales. source https://medicalxpress.com/news/2022-10-life-countries-big-falls.html

Why late-night eating leads to weight gain, diabetes

Northwestern Medicine scientists have uncovered the mechanism behind why eating late at night is linked to weight gain and diabetes. source https://medicalxpress.com/news/2022-10-late-night-weight-gain-diabetes.html

Enhanced Recovery After Surgery program enables same-day hip and knee replacement surgeries during pandemic

Adaptations to a program that helps ensure the best possible outcomes from surgery allowed eligible patients to receive their hip and knee replacement surgeries during the COVID-19 pandemic without spending the night in the hospital. The changes were so successful that they have been implemented permanently at the institution, according to a quality improvement study being presented at the Anesthesiology 2022 annual meeting. source https://medicalxpress.com/news/2022-10-recovery-surgery-enables-same-day-hip.html

Opioid abuse decreases during pandemic, yet higher rates persist for sexual minorities

Although opioid abuse in the U.S. is trending downward overall, it remains higher among non-heterosexuals than heterosexuals, according to an analysis of national survey data being presented at the Anesthesiology 2022 annual meeting. source https://medicalxpress.com/news/2022-10-opioid-abuse-decreases-pandemic-higher.html

Problems conceiving are not just about women. Male infertility is behind one in three IVF cycles

For the first time, IVF clinics in Australia and New Zealand have reported data about the scale and range of male fertility problems in couples who have IVF. New data released by the Australia and New Zealand Assisted Reproduction Database (ANZARD) today reveal about one-third of all IVF cycles performed in 2020 included a diagnosis of male infertility. source https://medicalxpress.com/news/2022-10-problems-women-male-infertility-ivf.html

Head and neck cancer researchers demonstrate the capability of a deep learning algorithm in the post-surgery setting

Artificial intelligence can augment current methods to predict the risk that head and neck cancer will spread outside the borders of neck lymph nodes, according to researchers with the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN). A customized deep learning algorithm using standard computed tomography (CT) scan images and associated data contributed by patients who participated in the E3311 phase 2 trial shows promise, especially for patients with a new diagnosis of human papillomavirus (HPV)-related head and neck cancer. The E3311 validated dataset carries the potential to contribute to the more accurate staging of disease and prediction of risk. source https://medicalxpress.com/news/2022-10-neck-cancer-capability-deep-algorithm.html

Sexual side effects of cancer treatment often unaddressed with female patients

A new study finds that sexual side effects of cancer treatment are discussed far less frequently with female patients than with male patients, even when the treatment directly affects sex organs. Among patients receiving brachytherapy for prostate or cervical cancer at a high-volume cancer center, 9 in 10 men were asked about their sexual health, compared to 1 in 10 women. The study, which also found a smaller but similar disparity in clinical trials nationwide, will be presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting. source https://medicalxpress.com/news/2022-10-sexual-side-effects-cancer-treatment.html

Unlocking the mysteries of tauopathies: A protein that gives hope

A mechanism has been found that controls cellular levels of tau, a protein whose abnormal accumulation is at the root of tauopathies, a class of devastating neurodegenerative diseases. source https://medicalxpress.com/news/2022-10-mysteries-tauopathies-protein.html

Microbiome: Disruption of gut microbial balance is associated with increased mortality after kidney, liver transplants

Disruptions in the gut microbiome have been linked to lower survival rates for people who have undergone kidney and liver transplants, a finding that highlights the critical importance of the vast and complex microbial communities that dwell within us. source https://medicalxpress.com/news/2022-10-microbiome-disruption-gut-microbial-mortality.html

Chronic Spontaneous Urticaria: What to Know

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What you should know about chronic spontaneous urticaria (CSU), including symptoms, triggers, treatment, and a link to autoimmune disease. source https://www.webmd.com/features/urticaria-chronic-spontaneous?src=RSS_PUBLIC

You Could Have Thyroid Eye Disease

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Are your eyes dry, uncomfortable, and bulging? You could have thyroid eye disease, especially if you already have Graves’ disease. Learn more about TED. source https://www.webmd.com/eye-health/features/could-be-thyroid-disease?src=RSS_PUBLIC

'Robbing women': Japan's sperm donation law spurs controversy

Satoko Nagamura and her girlfriend conceived their son with donated sperm, but new legislation in Japan could effectively outlaw the procedure for lesbian couples and single women. source https://medicalxpress.com/news/2022-10-women-japan-sperm-donation-law.html

Nutrition education should be 'on the menu' of all healthcare professionals' education—new research

All healthcare professionals should study a curriculum of nutrition education during their studies in order to help better support public health—new paper suggests. source https://medicalxpress.com/news/2022-10-nutrition-menu-healthcare-professionals-educationnew.html

Cellular 'Fix' treatment shows promise against ALS in small study

Researchers have made early progress toward a new approach to treating the deadly brain disease amyotrophic lateral sclerosis (ALS): using patients' own immune system T cells. source https://medicalxpress.com/news/2022-10-cellular-treatment-als-small.html

Experts say time is most critical factor for better stroke outcomes

When it comes to strokes, every second counts. Mayo Clinic experts explain how to recognize the signs of a stroke and how to reduce stroke risk. source https://medicalxpress.com/news/2022-10-experts-critical-factor-outcomes.html

Metabolite from pomegranates improves the function of immune cells in their fight against cancer

Researchers from the Georg-Speyer-Haus in Frankfurt am Main, Germany, were able to identify a new approach for the therapy of colorectal cancer (CRC) as part of an interdisciplinary project of the LOEWE Center Frankfurt Cancer Institute (FCI). In preclinical models as well as in studies on human immune cells, they found that urolithin A, a metabolite product of the pomegranate, sustainably improves the function of immune cells in their combat against cancer. source https://medicalxpress.com/news/2022-10-metabolite-pomegranates-function-immune-cells.html

Robotic suit gives paralyzed children gift of walking

Wearing a robotic exoskeleton designed specially for children, an eight-year-old boy with cerebral palsy walked through a therapy room in Mexico City, smiling triumphantly at the once-unthinkable feat. source https://medicalxpress.com/news/2022-10-robotic-paralyzed-children-gift.html

US clears Novavax COVID booster dose

U.S. regulators on Wednesday authorized a booster dose of the COVID-19 vaccine made by Novavax. source https://medicalxpress.com/news/2022-10-novavax-covid-booster-dose.html

Cholera outbreaks in six regions of Kenya: health ministry

Six regions in Kenya have been hit with cholera outbreaks including the capital Nairobi, the health ministry announced Wednesday, with a total of 60 cases registered nationwide. source https://medicalxpress.com/news/2022-10-cholera-outbreaks-regions-kenya-health.html

Study finds caregiver-child relationships improved after seven-session intervention

Only about 25 percent of children with challenging behaviors receive mental health treatment, and dropout rates are high for those who do. This makes brief and effective intervention programs to improve relationships between children and their caregivers needed. source https://medicalxpress.com/news/2022-10-caregiver-child-relationships-seven-session-intervention.html

ACR TI-RADS and deep learning algorithm guide diagnoses of pediatric thyroid nodules on ultrasound

According to an accepted manuscript published in the American Journal of Roentgenology (AJR), ACR TI-RADS and a deep learning algorithm trained on adult populations offer alternative strategies for evaluating thyroid nodules in children and younger adults, including guiding decisions to perform fine-needle aspiration. source https://medicalxpress.com/news/2022-10-acr-ti-rads-deep-algorithm-pediatric.html

Marijuana, meth, cocaine and opiate use are linked to atrial fibrillation

A new study by UC San Francisco researchers of more than 23 million people concludes that some commonly used and abused drugs pose previously unidentified risks for the development of atrial fibrillation (AF), a potentially deadly heart-rhythm disorder. source https://medicalxpress.com/news/2022-10-marijuana-meth-cocaine-opiate-linked.html

Researchers supercharge brain stimulation by repurposing an antibiotic

University of Calgary researchers have shown that the antibiotic D-Cycloserine (DCS) increases the effectiveness of transcranial magnetic stimulation (TMS) for people with major depressive disorder (MDD). TMS is a non-invasive, well-recognized therapy for people who have treatment resistant depression. Even so, it doesn't work for everyone. Researchers suspect the problem may be connected to a process in the brain essential for learning and memory. source https://medicalxpress.com/news/2022-10-supercharge-brain-repurposing-antibiotic.html

Hair Straightening Products Linked to Uterine Cancer Risk: Study

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Women who use chemical hair straightening products may be at an increased risk for uterine cancer, according to new research. source https://www.webmd.com/beauty/news/20221018/hair-straightening-products-linked-uterine-cancer-risk-study?src=RSS_PUBLIC

Health insurance companies overpay for some hospital radiology services

Health insurance companies may be overpaying for common radiology services, according to a study published in Radiology. source https://medicalxpress.com/news/2022-10-health-companies-overpay-hospital-radiology.html

Can FOMO Drive You to Drink?

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A study linked “fear of missing out” to misconduct, drug and alcohol use, and breaking the law among college students – adding to growing research on the potential harms of FOMO. source https://www.webmd.com/mental-health/addiction/news/20221018/can-fomo-drive-you-to-drink?src=RSS_PUBLIC

Risk of infant gastrointestinal tract exposure to pathogenic viruses of vaginal origin during delivery

Both the gut microbiome and virome of early life have always drawn research attention because they are strongly associated with the health status of an individual in the future. The gut virome, consisting of phages and eukaryotic viruses, directly or indirectly affects infant and child health. As the dominant component in gut virome, phages shape the microbiota in early life by preying on bacteria. source https://medicalxpress.com/news/2022-10-infant-gastrointestinal-tract-exposure-pathogenic.html

Alone Together: Caregivers and Loved Ones Struggle With Alzheimer’s

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Day after day, year after year, the struggles caregivers face, both big and small, take their toll. source https://www.webmd.com/alzheimers/features/alzheimers-caregivers?src=RSS_PUBLIC

Psoriasis does not appear to increase heart attack risk in people with significant kidney disease

Studies have suggested that psoriasis is an independent risk factor for heart attack in the general population, but investigators have made the surprising finding that in people who also have end-stage renal disease, which shares many risk factors with heart disease, it is not. source https://medicalxpress.com/news/2022-10-psoriasis-heart-people-significant-kidney.html

Study identifies new gene that drives colon cancer

Researchers at Mount Sinai's Tisch Cancer Institute have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor can contribute to the growth of tumor cells. The scientists reported these findings in Nature Communications. source https://medicalxpress.com/news/2022-10-gene-colon-cancer.html

Hospital emergency departments lack policy and strategies for spotting child neglect or abuse

In a survey of emergency department staff from across Europe, only around half said their hospital has a policy in place to help staff identify children who are being neglected or abused. source https://medicalxpress.com/news/2022-10-hospital-emergency-departments-lack-policy.html

In sub-Saharan Africa and South Asia, young children dying at greater-than-expected rates

Generally, as people age, the rate of mortality increases. Yet there's one period, the timeframe between a child's first day of life and age five, when mortality tends to decrease as the child gets older. source https://medicalxpress.com/news/2022-10-sub-saharan-africa-south-asia-young.html

New tool helps scientist understand how MRSA superbug avoids immune detection

A tool that promises to throw light on the strategies adopted by MRSA to avoid detection by the body's immune system has been developed at the University of Bath. source https://medicalxpress.com/news/2022-10-tool-scientist-mrsa-superbug-immune.html

Increased mitochondria and lipid turnover reduces risk for liver cancer

Alcohol consumption and hepatitis C viral infection are known risk factors for causing hepatocellular carcinoma, the most common form of liver cancer. Apart from these, obesity-associated nonalcoholic fatty liver disease has emerged as a major contributing factor for hepatocellular carcinoma in Western societies. The mechanisms underlying obesity-induced liver cancer are not well understood. source https://medicalxpress.com/news/2022-10-mitochondria-lipid-turnover-liver-cancer.html

How the reward system in the brain processes risky decisions

The mechanisms underlying decision-making have been a long-standing focus of neuroscience research. But now, researchers from Japan have found new information about how the reward system in the brain processes risky decisions. source https://medicalxpress.com/news/2022-10-reward-brain-risky-decisions.html

Should You Stay or Go? When to Change Treatments

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Advice from rheumatologists for changing psoriatic arthritis medications, including side effects, symptoms, and insurance coverage. source https://www.webmd.com/arthritis/psoriatic-arthritis/features/medications-risks-benefits?src=RSS_PUBLIC

Survey: Many US women lack basic information on life after mastectomy

As many as 50 percent of cancer patients who've undergone a mastectomy have elected to have breast reconstruction surgery. Yet, while breast reconstruction is a common procedure, a new national survey finds that many women may have not received adequate information to evaluate how it may impact them physically, financially and emotionally. source https://medicalxpress.com/news/2022-10-survey-women-lack-basic-life.html

Fewer patients sent to hospital rehabilitation facilities after colorectal operations early in the COVID pandemic

The first months of the COVID pandemic had a profound effect on hospital discharge practices and use patterns for patients with colorectal disease, according to findings presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022. A study of more than 100,000 surgical patients who underwent procedures for colorectal cancer found that they had 40% lower odds of being discharged to post-hospital rehabilitation during the pandemic than before. source https://medicalxpress.com/news/2022-10-patients-hospital-facilities-colorectal-early.html

Telemedicine reduces odds of no-show clinic visits by more than two-thirds for surgical patients

Surgical patients who use telehealth services are much more likely to show up for their initial clinic visit or follow-up appointment during the post-surgery period than those who rely on in-person visits only. Research findings were presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022. During the early months of the COVID pandemic, when everything shut down, telemedicine became an effective tool to reach patients. Building on those successes, more hospitals and clinics are implementing telehealth technology into their patient care practices. source https://medicalxpress.com/news/2022-10-telemedicine-odds-no-show-clinic-two-thirds.html

Operations for diverticulitis decreased in 2020, but the degree of disease severity increased

The first year of the COVID pandemic significantly altered how patients and providers treated diverticulitis, causing a significant drop in operations to manage the disease but a corresponding increase in the proportion of more severe cases and the need for emergency surgery, according to results of a nationwide study presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022. source https://medicalxpress.com/news/2022-10-diverticulitis-decreased-degree-disease-severity.html

Hospital room features may impact clinical outcomes for patients after surgery

Certain hospital room features, such as having a window view and distance from a nursing station, may influence clinical outcomes after undergoing high-risk operations, according to research findings presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022. source https://medicalxpress.com/news/2022-10-hospital-room-features-impact-clinical.html

Study finds less expensive noninvasive test is an effective alternative for colorectal cancer screening

Commercially available noninvasive screening tests for colorectal cancer—a fecal immunochemical test (FIT) and the multi-target stool DNAtest (mt-sDNA; or Cologuard®)—are equally effective for screening patients with early-stage colorectal cancer. However, a FIT costs about one-fifth of the multi-target DNA test, according to new study results presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022. source https://medicalxpress.com/news/2022-10-expensive-noninvasive-effective-alternative-colorectal.html

New palliative care screening tool for surgical ICU patients may facilitate decision-making processes

To aid in decision-making processes and increase awareness around palliative care in the Surgical Intensive Care Unit (SICU), a research team at the University of North Carolina at Chapel Hill (UNC-Chapel Hill) has developed a screening tool to identify—within seconds—patients who may benefit from palliative care consultations or goals of care discussions. Their research findings, presented at the Scientific Forum during the American College of Surgeons (ACS) Clinical Congress 2022, show that the screening tool successfully identified SICU patients who were later deemed candidates for palliative care by their medical team. source https://medicalxpress.com/news/2022-10-palliative-screening-tool-surgical-icu.html

'Sentient' brain cells in dish learn to play video game: study

Brain cells living in a dish can learn to play the classic video game Pong, thus demonstrating "intelligent and sentient behavior," Australian neuroscientists argue in a new paper. source https://medicalxpress.com/news/2022-10-sentient-brain-cells-dish-video.html

Uganda locks down 2 districts in bid to stem spread of Ebola

Ugandan authorities on Saturday imposed a travel lockdown on two Ebola-hit districts as part of efforts to stop the spread of the contagious disease. source https://medicalxpress.com/news/2022-10-uganda-districts-stem-ebola.html

Patients with clinical depression 'stopped seeking treatment' during the COVID waves

In the first study of its kind, German researchers have shown that the COVID pandemic saw a huge drop in the number of patients being admitted to hospital for clinical depression. Independently of these national statistics, the researchers found that the number of outpatients they dealt with increased over the same period in their department. As inpatient treatment offers more intensive levels of care, this implies that many patients did not receive care appropriate to their condition. It is not yet known if this shift in treatment is also seen in other countries. source https://medicalxpress.com/news/2022-10-patients-clinical-depression-treatment-covid.html

How bad is red meat for you? Health risks get star ratings

Research about what is healthy comes so thick and fast—red meat can appear good for you one week, stroke-inducing the next—that a confused public often struggles to keep up. source https://medicalxpress.com/news/2022-10-bad-red-meat-health-star.html

Scientists reappraise the role of 'zombie' cells that anti-aging medicine has sought to eliminate

Not all senescent cells are harmful "zombies" that should be wiped out to prevent age-related disease, according to new research from UC San Francisco, which found that some of them are embedded in young, healthy tissues and promote normal repair from damage. source https://medicalxpress.com/news/2022-10-scientists-reappraise-role-zombie-cells.html

Study validates diagnostic assay for Asian cancers

A Singapore research team of clinicians and scientists has validated a cancer diagnostic assay designed with Asian-centric biomarkers that aims to enable early diagnosis and timely treatment delivery. These findings, published in the journal Frontiers in Molecular Biosciences on September 21, 2022, supports the assay's use for making critical diagnoses and well-informed therapeutic decisions for Asian prevalent cancers. source https://medicalxpress.com/news/2022-10-validates-diagnostic-assay-asian-cancers.html

Development of an automatable highly sensitive method for coronavirus detection in wastewater

AdvanSentinel Inc., Shionogi & Co., Ltd., and Masaaki Kitajima, associate professor at the Faculty of Engineering, Hokkaido University have developed a highly sensitive detection technology for SARS-CoV-2 RNA in wastewater, in which most of the steps are compatible with automation. source https://medicalxpress.com/news/2022-10-automatable-highly-sensitive-method-coronavirus.html

New guidelines recommend screening children 8 to 18 for anxiety disorders

According to the CDC, 9.4% of children and adolescents had an anxiety disorder in 2019. Up to one in five youth aged 18 or younger will experience a mental health condition at some point in their lives. source https://medicalxpress.com/news/2022-10-guidelines-screening-children-anxiety-disorders.html

Gene associated with better immune response, protection after COVID-19 vaccination

Researchers from the University of Oxford have today reported new findings from a study exploring how certain genes can help generate a strong immune response following vaccination with two commonly used COVID-19 vaccines—identifying a particular gene associated with a high antibody response. source https://medicalxpress.com/news/2022-10-gene-immune-response-covid-vaccination.html

Secret structure in the wiring diagram of the brain

In the brain, our perception arises from a complex interplay of neurons that are connected via synapses. But the number and strength of connections between certain types of neurons can vary. Researchers from the University Hospital Bonn (UKB), the University Medical Center Mainz and the Ludwig-Maximilians-University Munich (LMU), together with a research team from the Max Planck Institute for Brain Research in Frankfurt, as part of the Priority Program Computational Connectomics (SPP2041), have now discovered that the structure of the seemingly irregular neuronal connection strengths contains a hidden order. This is essential for the stability of the neuronal network. The study has now been published in the journal PNAS. source https://medicalxpress.com/news/2022-10-secret-wiring-diagram-brain.html

Europe's high mortality linked to antimicrobial resistance needs action now

The latest and most comprehensive analysis of antimicrobial resistance (AMR) and its impact in the entire WHO European Region (53 countries) was published in a paper today in The Lancet Public Health. Researchers at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington's School of Medicine, Oxford Center for Global Health Research, Center for Tropical Medicine and Global Health, and other collaborators analyzed 23 bacterial pathogens and 88 pathogen-drug combinations to release the following findings: source https://medicalxpress.com/news/2022-10-europe-high-mortality-linked-antimicrobial.html

Talk therapy could improve mental health of people with dementia

People living with dementia may benefit from talking therapies available on the NHS, if they suffer from anxiety or depression, finds a new study led by UCL researchers. source https://medicalxpress.com/news/2022-10-therapy-mental-health-people-dementia.html

EXPLAINER: How iodine tablets block some nuclear radiation

The war in Ukraine has heightened fears about nuclear exposure—and interest in iodine pills that can help protect the body from some radiation. source https://medicalxpress.com/news/2022-10-iodine-tablets-block-nuclear.html

Most National Grocery Chains Fail Antibiotics-in-Meat Test

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Three-quarters of the largest grocery chains in the U.S. are failing to limit the use of antibiotics in their house-brand fresh meat, thus contributing to the spread of antibiotic resistance. source https://www.webmd.com/diet/news/20221012/most-national-grocery-chains-fail-antibiotics-in-meat-test?src=RSS_PUBLIC

Symptoms, quality of life important to guide treatment for peripheral artery disease (PAD)

For the approximately 8.5 million people in the U.S. living with peripheral artery disease (PAD—pronounced P-A-D), which is narrowed or clogged arteries in the legs, treatment decisions and criteria for success should be led by their symptoms and self-reported quality of life, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation. An American Heart Association scientific statement is an expert analysis of current research and may inform future treatment guidelines. source https://medicalxpress.com/news/2022-10-symptoms-quality-life-important-treatment.html

Statistical oversight could explain inconsistencies in nutritional research

People often wonder why one nutritional study tells them that eating too many eggs, for instance, will lead to heart disease and another tells them the opposite. The answer to this and other conflicting food studies may lie in the use of statistics, according to a report published today in the American Journal of Clinical Nutrition. source https://medicalxpress.com/news/2022-10-statistical-oversight-inconsistencies-nutritional.html

New device for early detection of gum disease

Researchers from the University of Birmingham are developing a rapid test for gum disease, and they expect the technology—a probe for use in point of care settings such as dental surgeries or pharmacies—to play a pivotal role in early detection of heart or lung disease, type 2 diabetes and rheumatoid arthritis. source https://medicalxpress.com/news/2022-10-device-early-gum-disease.html

People in the UK have higher probabilities of dying than predicted, new report finds

Men and women in the UK have a higher probability of dying than predicted, a new report has found. The results, published in European Actuarial Journal, could have a big impact on the future viability of pensions schemes. The research from Bayes Business School, which looks at death rates for people aged 50 to 95, paints a bleak picture for men and women in the UK. source https://medicalxpress.com/news/2022-10-people-uk-higher-probabilities-dying.html

Research finds that two out of five adults who use cigarettes smoke menthol

Menthol use has increased over the past decade among U.S. adults who smoke cigarettes, according to a study released by Columbia University Mailman School of Public Health and The City University of New York. Menthol use is much more common among adult smokers who are younger, from racial/ethnic minoritized groups and with mental health problems. The results are published in the journal Nicotine and Tobacco Research. source https://medicalxpress.com/news/2022-10-adults-cigarettes-menthol.html

Scarred Lungs and Landscapes: What’s Left When Lakes Vanish

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As lakes dry up around the world, they create a host of problems for the people near their former shorelines – including respiratory illnesses. source https://www.webmd.com/lung/copd/features/vanishing-lakes?src=RSS_PUBLIC

Small-molecule drug reverses neural effects of concussion

A small molecule called ISRIB that was identified at UC San Francisco can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research has found. source https://medicalxpress.com/news/2022-10-small-molecule-drug-reverses-neural-effects.html

White House: Get new booster by Halloween for safer holidays

The White House on Tuesday said eligible Americans should get the updated COVID-19 boosters by Halloween to have maximum protection against the coronavirus by Thanksgiving and the holidays, as it warned of a "challenging" virus season ahead. source https://medicalxpress.com/news/2022-10-white-house-booster-halloween-safer.html

Stable electrodes for long-term, wearable brain-machine interface

Wearable medical devices are an important part of the future of medicine and a key focus of researchers around the world. They open the door for long-term continuous monitoring of patients outside of the medical setting to give clinicians an accurate picture of what's happening and a better chance to effectively treat their ailments. source https://medicalxpress.com/news/2022-10-stable-electrodes-long-term-wearable-brain-machine.html

Survey: Most women unaware of the signs of an aggressive form of breast cancer

October is National Breast Cancer Awareness Month, and a new national survey commissioned by The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) found that most women are unaware of the unusual symptoms of a particularly aggressive and deadly form of the disease known as inflammatory breast cancer. source https://medicalxpress.com/news/2022-10-survey-women-unaware-aggressive-breast.html

Does a history of migraines mean women are more likely to be poor sleepers?

Women are, unfortunately, more likely to get migraines and suffer from poor sleep than men, and the problems only get worse as women transition through menopause. A new study evaluates the association of migraine and sleep quality in premenopausal compared with perimenopausal women. Study results will be presented during The North American Menopause Society (NAMS) Annual Meeting in Atlanta, October 12-15, 2022. source https://medicalxpress.com/news/2022-10-history-migraines-women-poor-sleepers.html

Military law enforcement key to convincing service members to safely store firearms

Service members are more likely to store firearms safely when the message on safe storage is delivered by military law enforcement, according to a Rutgers study. source https://medicalxpress.com/news/2022-10-military-law-key-convincing-members.html

Long-term impacts of famine include health and socioeconomic challenges

Millions of children are exposed to extreme hunger each year, but children who experience malnutrition are more likely to have poorer health and developmental delays that persist into old age, according to previous research findings. Researchers at Penn State recently examined the results of early-life exposures to famine and malnutrition and found numerous impacts on health and socioeconomic attainment, especially among males. source https://medicalxpress.com/news/2022-10-long-term-impacts-famine-health-socioeconomic.html

Opioids and tranquilizers still frequently prescribed to patients with alcohol use disorder in NY

Prescribing rates of opioids and tranquilizers to people undergoing treatment for alcohol abuse in New York remains high, despite public efforts to curb prescribing practices, according to a new University at Buffalo-led study. source https://medicalxpress.com/news/2022-10-opioids-tranquilizers-frequently-patients-alcohol.html

Patient-specific mathematical model determines how aneurysm shape and size influence growth and rupture

Cerebral aneurysms appear in 5% to 8% of the general population. The blood vessel rupture and resultant blood leakage within the brain can lead to severe stroke or fatal consequences. More than one quarter of patients who experience a hemorrhagic stroke die before reaching a health care facility. source https://medicalxpress.com/news/2022-10-patient-specific-mathematical-aneurysm-size-growth.html

Study shows some children with homozygous familial hypercholesterolemia miss out on decades of life-saving treatment

The Family Heart Foundation, a leading research and advocacy organization, has shared results from an analysis of patients in its CASCADE FH Registry showing that children with homozygous familial hypercholesterolemia (HoFH) are diagnosed earlier and have much higher untreated low-density lipoprotein cholesterol (LDL-C) than adults with HoFH. source https://medicalxpress.com/news/2022-10-children-homozygous-familial-hypercholesterolemia-decades.html

New survey: 91% of parents say their family is less stressed when they eat together

Chronic, constant stress can increase lifetime risk of heart disease and stroke, but a new survey from the American Heart Association, a global force for longer, healthier lives for all, reveals regular mealtime with others could be a simple solution to help manage stress. source https://medicalxpress.com/news/2022-10-survey-parents-family-stressed.html

ACP says federal government needs to improve health support for indigenous communities

Indigenous populations continue to suffer significant barriers and disparities in health care, due in part to the federal government failing to provide adequate health support and services for these communities, says the American College of Physicians (ACP) in a new position paper. ACP says that policymakers have an obligation to fulfill the federal trust responsibility to provide equitable health care and other services to Indigenous populations in the U.S., including sufficient financial resources to support their care. The full position paper is published in Annals of Internal Medicine. source https://medicalxpress.com/news/2022-10-acp-federal-health-indigenous.html

Electronic gaming can trigger potentially lethal heart rhythm problems in susceptible children

Electronic gaming can precipitate life-threatening cardiac arrhythmias in susceptible children whose predisposition may have been previously unrecognized, according to a new report in Heart Rhythm. The investigators documented an uncommon but distinct pattern among children who lose consciousness while playing electronic (video) games. source https://medicalxpress.com/news/2022-10-electronic-gaming-trigger-potentially-lethal.html

What Is Cuffing Season?

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As the weather turns chilly, “cuffing season” starts for relationships. What exactly does that mean? Find out. source https://www.webmd.com/sex-relationships/features/what-is-cuffing-season?src=RSS_PUBLIC

Ratio shift of protein in brain cells causes changes underlying early cognitive decline

Early cognitive decline may result from a shift in the ratio of a protein sub-type in our brain cells triggering cell-loss. This new study, published in Scientific Reports, shows how this might be caused. The discovery provides a new therapeutic target to prevent the onset of neurodegenerative diseases including dementia and Alzheimer's. source https://medicalxpress.com/news/2022-10-ratio-shift-protein-brain-cells.html

How genetics influences our body weight beyond genes

Heredity plays a role in how strongly we are predisposed to put on excess weight. In recent years, researchers have extensively examined which genes and gene variants play a role in this, and have identified roughly one hundred obesity susceptibility genes. However, genome-wide association studies have shown that less than half of all cases of hereditary obesity can be explained by these genes. The other half are the result of factors that, although part of our DNA, are not genes in the classical sense. Epigenetic information would be one example of such a factor. source https://medicalxpress.com/news/2022-10-genetics-body-weight-genes.html

Financial toxicity after robotic prostate cancer surgery: Younger patients at higher risk

Among men undergoing robot-assisted radical prostatectomy (RARP) for treatment of prostate cancer, younger patients are more likely to experience cancer-related financial toxicity, suggests a study in the Journal of Urology, an official journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. source https://medicalxpress.com/news/2022-10-financial-toxicity-robotic-prostate-cancer.html

Research finds association between plasma metabolites and COVID-19 antibody levels in recovered patients

A study led by Hong Kong Baptist University (HKBU) has revealed the association between rapidly fading antibody levels in some recovered COVID-19 patients and a high plasma concentration of a metabolite called glycylproline (gly-pro) and its producing enzyme. source https://medicalxpress.com/news/2022-10-association-plasma-metabolites-covid-antibody.html

Identifying the underlying causes of ovarian cancer

Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women's tumors do not respond to therapy. source https://medicalxpress.com/news/2022-10-underlying-ovarian-cancer.html

What Is Cuffing Season?

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As the weather turns chilly, “cuffing season” starts for relationships. What exactly does that mean? Find out. source https://www.webmd.com/features/what-is-cuffing-season?src=RSS_PUBLIC

China imposes lockdowns as COVID-19 surges after holiday

Chinese cities were imposing fresh lockdowns and travel restrictions after the number of new daily COVID-19 cases tripled during a weeklong holiday, ahead of a major Communist Party meeting in Beijing next week. source https://medicalxpress.com/news/2022-10-china-imposes-lockdowns-covid-surges.html

Telemedicine was made easy during COVID-19. Not any more

Telemedicine exploded in popularity after COVID-19 hit, but limits are returning for care delivered across state lines. source https://medicalxpress.com/news/2022-10-telemedicine-easy-covid-.html

Dinner at 5 p.m.? New research suggests eating early and within a 10-hour window is healthier

Researchers have provided more evidence that eating earlier in the day might be good for you—and eating all of your meals within a 10-hour window could be healthier, too. source https://medicalxpress.com/news/2022-10-dinner-pm-early-hour-window.html

Rugby players face highly increased MND risk: disease study

Rugby chiefs must take urgent action to reduce head injuries after a study indicated that former international players are 15 times more likely to develop motor neurone disease, researchers said Tuesday. source https://medicalxpress.com/news/2022-10-rugby-players-highly-mnd-disease.html

CDC to Switch From Daily to Weekly COVID Data Updates

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The U.S. Centers for Disease Control and Prevention says it will start updating COVID-19 case and death counts on a weekly instead of a daily basis starting Oct. 20. source https://www.webmd.com/lung/news/20221008/cdc-to-switch-from-daily-to-weekly-covid-data-updates?src=RSS_PUBLIC

Firearms violence prevention demands a public safety approach like regulation of motor vehicles

Each day, 28 U.S. children and teens —the equivalent of a high school classroom—die from gun violence, making it the No. 1 killer of youth through age 24. The national death rate is significantly higher than all other high-income countries combined, largely due to an alarming increase in suicides and homicides that do not make national headlines. source https://medicalxpress.com/news/2022-10-firearms-violence-demands-safety-approach.html

Consensus report on benefits, challenges and recommendations for automated insulin delivery

A new consensus report addressing the benefits, challenges, and recommendations related to automated insulin delivery (AID) is being launched today by two leading diabetes organizations—the European Association for the Study of Diabetes (EASD) and the American Diabetes Association (ADA). The joint Diabetes Technology Working Group of the EASD and ADA created this consensus report to provide a review of the current landscape of AID systems as well as recommended targeted actions. source https://medicalxpress.com/news/2022-10-consensus-benefits-automated-insulin-delivery.html

Mapping human brain development

The human brain is probably the most complex organ in the entire living world and has long been an object of fascination for researchers. However, studying the brain, and especially the genes and molecular switches that regulate and direct its development, is no easy task. source https://medicalxpress.com/news/2022-10-human-brain.html

Iron deficiency suppresses important arm of the innate immune system

Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. At the same time, surprisingly, a cell type of the innate immune defense, the neutrophils, also dramatically decreases, as scientists from the German Cancer Research Center now have shown for the first time. Iron deficiency, a known defense mechanism against infectious pathogens, is a double edged sword, as it simultaneously curbs the defensive power of an important arm of the innate immune system. source https://medicalxpress.com/news/2022-10-iron-deficiency-suppresses-important-arm.html

3D map reveals DNA organization within human retina cells

National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell's nucleus. The resulting comprehensive gene regulatory network provides insights into regulation of gene expression in general, and in retinal function, in both rare and common eye diseases. The study is published in Nature Communications. source https://medicalxpress.com/news/2022-10-3d-reveals-dna-human-retina.html

India probing cough syrup linked to Gambia child deaths

Indian authorities are investigating cough syrups made by a local pharmaceutical company after the World Health Organisation said they could be responsible for the deaths of 66 children in The Gambia. source https://medicalxpress.com/news/2022-10-india-probing-syrup-linked-gambia.html

Number of children hospitalized for E-scooter injuries surge from 2011-2020

Standing electric scooters, commonly referred to as e-scooters, have been increasing in popularity across the country over the past decade. According to a new research abstract presented during the 2022 American Academy of Pediatrics National Conference & Exhibition, e-scooter injuries are becoming much more common and increasingly severe. source https://medicalxpress.com/news/2022-10-children-hospitalized-e-scooter-injuries-surge.html

US to begin screening travelers coming from Uganda for Ebola

The United States will begin screening travelers coming from Uganda for Ebola as an additional precaution aimed at trying to prevent an outbreak in the African country from spreading, the Biden administration said Thursday. source https://medicalxpress.com/news/2022-10-screening-uganda-ebola.html

Babies in Tigray dying at 4 times pre-war levels, study says

Babies in Ethiopia's embattled Tigray region are dying in their first month of life at four times the rate before the war cut off access to most medical care for over 5 million people, according to the most sweeping study yet of how mothers and children are suffering. source https://medicalxpress.com/news/2022-10-babies-tigray-dying-pre-war.html

COVID-19: Boosting with an mRNA vaccine offers better protection in people who received two doses of CoronaVac

One year after mass vaccination against COVID-19 was launched, inactivated virus vaccines accounted for half of the doses administered worldwide. Now, a large observational study performed in Brazil and co-led by Fiocruz and the Barcelona Institute for Global Health (ISGlobal), shows that in people who initially received two doses of the inactivated CoronaVac vaccine, an mRNA boost offers considerably better protection against mild and severe COVID-19 than a boost with the same vaccine. These findings, published in Nature Communications, have important implications for guiding boosting strategies in countries where most of the population received inactivated virus vaccines. source https://medicalxpress.com/news/2022-10-covid-boosting-mrna-vaccine-people.html

Referrals to long COVID clinic fall by 79% following roll-out of the vaccine

Referrals to Cambridge's long COVID clinic fell dramatically in the period August 2021 to June 2022, which researchers say is likely due to the successful rollout of the vaccine. source https://medicalxpress.com/news/2022-10-referrals-covid-clinic-fall-roll-out.html

Liver cancer cases and deaths projected to rise by more than 55% by 2040

A new analysis reveals that primary liver cancer was among the top three causes of cancer death in 46 countries in 2020 and the number of people diagnosed with or dying from primary liver cancer per year could rise by more than 55% by 2040. Investigators call for efforts to control the disease to be prioritized in a new study in the Journal of Hepatology. source https://medicalxpress.com/news/2022-10-liver-cancer-cases-deaths.html

Survival is a mixed matter for deadliest of pancreatic cancers

Pancreatic ductal adenocarcinoma (PDAC) is the most common and most lethal form of pancreatic cancer. The overall 5-year survival for patients with PDAC is just 7.1 percent. source https://medicalxpress.com/news/2022-10-survival-deadliest-pancreatic-cancers.html

China's vast Xinjiang hit with COVID-19 travel restrictions

Sprawling Xinjiang is the latest Chinese region to be hit with sweeping COVID-19 travel restrictions, as China further ratchets up control measures ahead of a key Communist Party congress later this month. source https://medicalxpress.com/news/2022-10-china-vast-xinjiang-covid-restrictions.html

At least 66 US clinics have halted abortions, institute says

At least 66 clinics in 15 states have stopped providing abortions since the U.S. Supreme Court overturned Roe v. Wade, according to an analysis released Thursday. source https://medicalxpress.com/news/2022-10-clinics-halted-abortions.html

Wear and tear from lifelong stress can increase cancer mortality

The wear and tear on the body from chronic and lifelong stress can also lead to an increased risk of dying from cancer, Medical College of Georgia researchers report. source https://medicalxpress.com/news/2022-10-lifelong-stress-cancer-mortality.html

Health worker burnout and 'compassion fatigue' put patients at risk

The toll of COVID on our health care workers has been brutal, with many saying they want to quit their jobs. source https://medicalxpress.com/news/2022-10-health-worker-burnout-compassion-fatigue.html

Particle radioactivity linked to pollution-associated heart attack and stroke death

Particle radioactivity, a characteristic of air pollution that reflects the colorless, odorless gas radon found in fine particulate matter (PM2.5) air pollution, enhances PM2.5 toxicity and increases risk of death from cardiovascular disease, especially from heart attack or stroke, according to new research published today in the Journal of the American Heart Association. source https://medicalxpress.com/news/2022-10-particle-radioactivity-linked-pollution-associated-heart.html

Parenting practices in teen years set the stage for closeness, warmth later on

High-quality parenting practices in adolescence lay the foundation for close parent-child relationships when the children become young adults, according to new research from Penn State. source https://medicalxpress.com/news/2022-10-parenting-teen-years-stage-warmth.html

Putting the brakes on heroin relapse

Neuroscientists from the Medical University of South Carolina (MUSC) report in Science Advances that star-shaped brain cells known as astrocytes can "turn off" neurons involved in relapse to heroin. Drug-related cues in the environment can intensify the drive to seek drugs, leading to relapse. In this article, a team led by Peter Kalivas, Ph.D., and Anna Kruyer, Ph.D., both of the Department of Neuroscience, examined how astrocytes interact with neurons and whether astrocytes play an important role in regulating the response to drug cues. source https://medicalxpress.com/news/2022-10-heroin-relapse.html

Do attitudes and behaviors in response to stress impact the health of older people with diabetes?

New research published in the Journal of the American Geriatrics Society suggests that psychological resilience—having attitudes and behaviors that help people bounce back after stressful challenges—may help older individuals with type 2 diabetes have fewer hospitalizations, better physical functioning, lower disability, better mental quality of life, and a lower likelihood of becoming frail. source https://medicalxpress.com/news/2022-10-attitudes-behaviors-response-stress-impact.html

Can paid parental leave help prevent newborn deaths?

A recent analysis published in Contemporary Economic Policy indicates that 6-week paid family leave in California saved 339 infants' lives from 2004–2008. source https://medicalxpress.com/news/2022-10-paid-parental-newborn-deaths.html

Can excessive physical activity during adolescence lead to problems with leg alignment?

A study published in the Journal of Orthopaedic Research used imaging tests to reveal that physical activity levels may impact adolescents' and young adults' leg alignment during development. source https://medicalxpress.com/news/2022-10-excessive-physical-adolescence-problems-leg.html

Uganda health worker dies of Ebola, raising toll to 10

Uganda on Wednesday confirmed the death of a health worker from Ebola, bringing the total number of fatalities from the highly contagious virus to 10. source https://medicalxpress.com/news/2022-10-uganda-health-worker-dies-ebola.html

Hospital readmission rate for younger women is higher than for younger men after a heart attack

In a new study of younger heart attack victims in Ontario, Canada, researchers found that the health care system delivers high quality care for younger heart attack survivors; however, there are still disparities between men and women. Cardiovascular and all-cause hospital readmission rates are higher in young women than young men. This underscores the need for ongoing efforts to improve prevention strategies, as risk factors for heart disease in young women continue to rise. Their findings appear in the Canadian Journal of Cardiology. source https://medicalxpress.com/news/2022-10-hospital-readmission-younger-women-higher.html

New computational technique reveals changes to lung function post COVID-19 infection

As a respiratory disease, COVID-19 infection mainly affects the lungs. While most people recover completely, a significant number of individuals experience symptoms that can persist for weeks or months post COVID infection, sometimes referred to as "long COVID." It remains unclear whether these symptoms are associated with any long-term damage that reduces the function of the lungs and respiratory system. source https://medicalxpress.com/news/2022-10-technique-reveals-lung-function-covid-.html

Specialized smart soft contact lenses can address global issue of glaucoma diagnosis, management

The vision of Purdue University biomedical engineer Chi Hwan Lee to develop specialized smart soft contact lenses that can accurately measure intraocular pressure (IOP) in a person's eye could be the latest answer to stopping glaucoma-related blindness. source https://medicalxpress.com/news/2022-10-specialized-smart-soft-contact-lenses.html

Study shows synergistic association between genetic and behavioral risks for liver disease

Excessive alcohol use and obesity are known to increase the risk for developing cirrhosis and liver cancer, but the risk is not the same for everyone with those factors. Researchers at Baylor College of Medicine found that a key genetic variant risk factor, PNPLA3, plays a synergistic role in increasing the risk for cirrhosis, liver cancer and liver-related death when combined with alcohol use and obesity. The findings were published today in JAMA Network Open. source https://medicalxpress.com/news/2022-10-synergistic-association-genetic-behavioral-liver.html

Study finds the mechanism used by metastatic cancer cells to infiltrate the liver

Metastasis—when cancer spreads to form new tumors—causes approximately 90% of cancer-related deaths. Because metastatic cancer cells circulate in the blood, the liver—which filters the blood—is considered the most vulnerable organ, so treatments that prevent liver metastasis are urgently needed. A team of Osaka Metropolitan University researchers discovered a mechanism that allows metastatic cancer cells to infiltrate the liver, and how that infiltration can be blocked by inhibiting a related protein. source https://medicalxpress.com/news/2022-10-mechanism-metastatic-cancer-cells-infiltrate.html

SGLT2 inhibitors and GLP1 receptor antagonists improve type-2 diabetes outcomes, but are not cost effective

A cost-effectiveness study of sodium–glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP1) receptor agonists has found that the use of these medications as first-line treatment for type-2 diabetes would improve outcomes, but their costs would need to decrease by at least 70 percent to be cost-effective. The study is published in Annals of Internal Medicine. source https://medicalxpress.com/news/2022-10-sglt2-inhibitors-glp1-receptor-antagonists.html

Investigating rare genetic mutations led scientists to surprising blood pressure discovery

The kidneys are often the unsung heroes in maintaining healthy blood pressure, filtering 180 liters of fluid and a pound of salt every day to keep levels in check. But new research by University of Pittsburgh geneticists and nephrologists shows that, surprisingly, a cellular channel outside the kidneys is doing some of the heavy lifting when it comes to keeping blood pressure under control. source https://medicalxpress.com/news/2022-10-rare-genetic-mutations-scientists-blood.html

No significant increase in Guillain-Barré syndrome after COVID-19 vaccination, researchers find

There is no evidence that the COVID-19 vaccination increases the incidence of Guillain-Barré syndrome, a rare neurological disorder in which the body's immune system attacks the nerves, according to a Rutgers-led study. source https://medicalxpress.com/news/2022-10-significant-guillain-barr-syndrome-covid-vaccination.html

New heart attack insight could lead to better survival rates after surgery

New research shows how doctors can improve the timing of surgery for some heart attack patients by analyzing the levels of a particular protein. source https://medicalxpress.com/news/2022-10-heart-insight-survival-surgery.html

Unique gene signature could help predict response to chemotherapy

Researchers at the Francis Crick Institute have developed a method that could help predict whether people with lung cancer will respond to chemotherapy, based on which genes are switched on in their tumor. source https://medicalxpress.com/news/2022-10-unique-gene-signature-response-chemotherapy.html

Significant antiviral activity of bulevirtide for treatment of chronic hepatitis D infection

Between 10 and 20 million people worldwide are infected with hepatitis D virus (HDV). HDV infection is always associated with hepatitis B virus infection. So far there has been no satisfactory therapeutic option for this most severe form of chronic viral hepatitis. In a multicenter Phase II clinical trial, an international research team was now able to show that the 24-week application of the drug candidate bulevirtide, developed by DZIF virologist Prof. Stephan Urban, significantly reduced hepatitis D viral load in blood serum and liver. Treatment with the novel entry inhibitor therefore represents a promising strategy for patients with chronic HDV infection. source https://medicalxpress.com/news/2022-10-significant-antiviral-bulevirtide-treatment-chronic.html

Study uncovers mechanisms of reactive oxygen species in stem cell function and inflammation prevention

Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could provide greater insights into the prevention and treatment of inflammatory bowel diseases (IBD), according to findings published in the journal Gut on October 3. source https://medicalxpress.com/news/2022-10-uncovers-mechanisms-reactive-oxygen-species.html

Recent winners of the Nobel Medicine Prize

Here is a list of the winners of the Nobel Medicine Prize in the past 10 years: source https://medicalxpress.com/news/2022-10-winners-nobel-medicine-prize.html

Nobel panel to announce winner of medicine prize

The winner, or winners, of the Nobel Prize in physiology or medicine will be announced Monday at the Karolinska Institute in Stockholm, Sweden. source https://medicalxpress.com/news/2022-10-nobel-panel-winner-medicine-prize.html

Which grains you eat can impact your risk of getting heart disease earlier

In one of the first studies to examine the relationship between different types of grain intake and premature coronary artery disease in the Middle East, researchers found a higher intake of refined grain was associated with an increased risk of premature coronary artery disease in an Iranian population, while eating whole grains was associated with reduced risk. The study will be presented at the American College of Cardiology (ACC) Middle East 2022 Together with the 13th Emirates Cardiac Society Congress, taking place in Dubai, United Arab Emirates, October 7-9, 2022. source https://medicalxpress.com/news/2022-10-grains-impact-heart-disease-earlier.html

Why do some kids take bigger risks than others?

Some kids are risk-takers. Others tend to play it safe. Are these differences simply based on personality, or do children's environments help shape their willingness to take a gamble? source https://medicalxpress.com/news/2022-09-kids-bigger.html

Study reveals main target of SARS-CoV-2 in brain and describes effects of virus on nervous system

A Brazilian study published in the journal PNAS describes some of the effects infection by SARS-CoV-2 can have on the central nervous system. A preliminary version (not yet peer-reviewed) posted in 2020 was one of the first to show that the virus that causes COVID-19 can infect brain cells, especially astrocytes. It also broke new ground by describing alterations in the structure of the cortex, the most neuron-rich brain region, even in cases of mild COVID-19. source https://medicalxpress.com/news/2022-09-reveals-main-sars-cov-brain-effects.html

Long Covid remains a mystery, though theories are emerging

Millions of people around the world are believed to suffer from long COVID yet little remains known about the condition—though research has recently proposed several theories for its cause. source https://medicalxpress.com/news/2022-10-covid-mystery-theories-emerging.html