Jason Lee

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease. The findings may offer a new potential target for therapies for the intractable condition. source https://medicalxpress.com/news/2022-11-role-alzheimer-disease-gene-brain.html

A minimally invasive treatment for carpal tunnel syndrome provides complete and long-term relief to patients without the use of corticosteroids, according to research being presented today at the annual meeting of the Radiological Society of North America (RSNA). source https://medicalxpress.com/news/2022-11-non-surgical-treatment-relieves-carpal-tunnel.html

An experimental Alzheimer's drug modestly slowed the brain disease's inevitable worsening, researchers reported Tuesday—but it remains unclear how much difference that might make in people's lives. source https://medicalxpress.com/news/2022-11-drug-alzheimer-real-difference.html

When a partner breaks up with them, men often try to make sense of it by telling themselves stories about how it happened. Some of these stories are more helpful than others in helping the men move forward, suggests new research by UBC men's health researcher and Canada Research Chair professor Dr. John Oliffe. source https://medicalxpress.com/news/2022-11-stories-men-dumped.html

High school students who have a large weekly allowance, friends who smoke and low levels of physical activity are more likely to use multiple substances over time. Conversely, being older, being Black and eating breakfast daily were factors associated with a smaller chance of transitioning to multiple use. source https://medicalxpress.com/news/2022-11-ai-method-health-analysis-trends.html

A diet rich in whole grains, which are naturally high in fiber, is associated with lowering a person's risk for various health problems. Overall, Americans are eating more whole-grain foods than ever before, researchers from the Friedman School of Nutrition Science and Policy at Tufts University report in a new study, published November 30 in the American Journal of Clinical Nutrition. However, the increase in whole-grain intake over the past two decades could be 39.5% or 61.5%, depending on which definition of a whole-grain food is being used. In addition, Americans' mean consumption of whole-grain foods remained far below the recommended consumption of at least three ounces each day and varied considerably by each definition. source https://medicalxpress.com/news/2022-11-americans-grains.html

LMU researchers have identified a protein that is involved in the regulation of immune cells and can curb the development of atherosclerosis. Their research is published in Nature Cardiovascular Research. source https://medicalxpress.com/news/2022-11-atherosclerosis-body-cells.html

Artificial intelligence-enabled eye scans could be used to rapidly and accurately predict whether a person is at high risk of heart disease, a new study involving researchers from London's Kingston University has established. source https://medicalxpress.com/news/2022-11-heart-disease-simple-eye-artificial.html

Cholangiocarcinomas (CCAs) are a highly aggressive and diverse group of malignancies of the biliary tract that currently account for 15% of all liver cancers and approximately 3% of gastrointestinal tumors. While rare, the incidence of CAA is on the rise globally. Often asymptomatic at early stages, CCA is usually diagnosed at advanced stage with a dismal prognosis and limited therapeutic options. The 5-year survival rate of patients with advanced metastatic disease is only 2%. There is therefore an urgent need to develop more effective therapies to improve clinical outcomes in this patient population. source https://medicalxpress.com/news/2022-11-team-large-cholangiocarcinoma-preclinical-drug.html

Soon after cholesterol and fat start depositing on the lining of the blood vessels that supply your heart, the smooth muscle cells that give the blood vessels strength and flexibility start to get bigger and multiply. source https://medicalxpress.com/news/2022-11-heart-disease.html

Pregnant women living in U.S. states where cannabis is legal must be screened for the drug, for the health of both mother and baby. This is the claim of scientists who in a new national study have found that these individuals are far more likely to use the substance. source https://medicalxpress.com/news/2022-11-pregnant-women-cannabis-usage-states.html

The number of organ donations and organ transplants goes up markedly during large motorcycle rallies, according to a newly published analysis led by researchers at Harvard Medical School and Massachusetts General Hospital. source https://medicalxpress.com/news/2022-11-donations-transplants-days-largest-motorcycle.html

Exposure therapy is one of the leading treatments for post-traumatic stress disorder (PTSD), but up to a half of all patients don't respond to it. source https://medicalxpress.com/news/2022-11-ten-minutes-aerobic-exposure-therapy.html

A new study led by UB researchers shows that wasteosomes—structures that act as containers for brain waste products—indicate a malfunction of the glymphatic system, a recently discovered system that is an important brain-cleaning mechanism. source https://medicalxpress.com/news/2022-11-marker-linked-malfunctioning-glymphatic.html

A common chemotherapy drug could carry a toxic inheritance for children and grandchildren of adolescent cancer survivors, Washington State University-led research indicates. source https://medicalxpress.com/news/2022-11-chemotherapy-disease-susceptibility-future-generations.html

Using MRI data from the largest long-term study of brain development and child health in the United States, researchers have found that higher weight and body mass index (BMI) in pre-adolescence are associated with poor brain health. The findings are being presented today at the annual meeting of the Radiological Society of North America (RSNA). source https://medicalxpress.com/news/2022-11-obesity-linked-poor-brain-health.html

Pakistani authorities launched a new nationwide anti-polio drive on Monday amid a spike in new cases among children, health officials said. It is the sixth such campaign this year and will last for five days, aiming to inoculate children under the age of 5 in high-risk areas. source https://medicalxpress.com/news/2022-11-pakistan-anti-polio-spike-cases.html

Uganda's president extended a six-week lockdown Saturday on two districts at the epicenter of an an Ebola outbreak that has claimed 55 lives but said its spread was being curbed. source https://medicalxpress.com/news/2022-11-uganda-ebola-lockdown-hotspots.html

Wastewater-based epidemiology has proven a useful tool for epidemiological monitoring during the COVID-19 pandemic. However, few quantitative models comparing virus concentrations in wastewater samples and cumulative incidence have been established. source https://medicalxpress.com/news/2022-11-relationship-sars-cov-wastewater-cumulative-incidence.html

People of South Asian ethnicity may be able to achieve type 2 diabetes remissions by following a structured weight management program, according to a new study which saw one third of participants lose more than 10% of their body weight. source https://medicalxpress.com/news/2022-11-south-asian-people-diabetes-remission.html

Optimizing health before pregnancy can improve health outcomes for both the mother and newborn baby. source https://medicalxpress.com/news/2022-11-family-importance-preconception-health.html

Professor Sue Davis, AO, is a pioneer and leading expert in women's health in Australia, which is why she has the letters after her name—an Officer of the Order of Australia, awarded last year. source https://medicalxpress.com/news/2022-11-menopause-politics-women-health.html

ETH Zurich researchers have found that a set of proteins have different shapes in the spinal fluid of healthy individuals and Parkinson's patients. These could be used in the future as a new type of biomarker for this disease. source https://medicalxpress.com/news/2022-11-protein-parkinson-disease.html

Mexico's Public Health Department said Thursday that a worrisome outbreak of 61 meningitis cases in the northern state of Durango this month was linked to anesthetic procedures used at local hospitals. source https://medicalxpress.com/news/2022-11-mexico-deadly-meningitis-outbreak-anesthetics.html

Zooming in on a single disease and studying it intensely is often the most productive route to finding treatments. But there's no easy way to distinguish among people living with any of the primary tauopathies—a group of rare brain diseases marked by rapidly worsening problems with thinking and movement—because the symptoms are too similar. As a result, most studies on primary tauopathies have included a mix of such diseases, even though researchers know that the diseases differ in important ways and probably require different treatments. source https://medicalxpress.com/news/2022-11-diagnostic-marker-deadly-brain-disease.html

Around one billion young people worldwide could be at risk of hearing loss from listening to headphones or attending loud music venues, a large review of the available research estimated on Wednesday. source https://medicalxpress.com/news/2022-11-billion-youth-loss-headphones-venues.html

The first comprehensive study to evaluate research on the mental health of children and young people using evidence that spanned before and during COVID-19 has found an impact on mental health that could result in an increased demand for support services. source https://medicalxpress.com/news/2022-11-pandemic-young-people-mental-health.html

A new, large-scale study of more than 20,000 older adults in Canada found that approximately 1 in 8 older adults developed depression for the first time during the pandemic. source https://medicalxpress.com/news/2022-11-older-adults-experienced-depression-covid-.html

A stark digital skills deficit among people with severe mental illness means they struggle to access key services which are increasingly online, according to research by scientists at the University of York. source https://medicalxpress.com/news/2022-11-digital-poses-exclusion-people-mental.html

Researchers at Karolinska Institutet in Sweden have identified the bacteria most commonly found in severe oral infections. Few such studies have been done before, and the team now hopes that the study can provide deeper insight into the association between oral bacteria and other diseases. The study is published in Microbiology Spectrum. source https://medicalxpress.com/news/2022-11-link-oral-bacteria-diseases.html

Machine learning can be used in the classification of health-drink preferences for older people, according to research published in the International Journal of Industrial and Systems Engineering. source https://medicalxpress.com/news/2022-11-machine-older-adults-healthy-option.html

Findings from a new study reveal that some unexpected conditions are leading to more hospitalizations in people living with type 2 diabetes compared to the general population. source https://medicalxpress.com/news/2022-11-excess-hospitalization-people-diabetes.html

Scientists affiliated with the Department of Physical Education's Human Movement Laboratory (Movi-Lab) at São Paulo State University (UNESP) in Bauru, Brazil, are using artificial intelligence to help diagnose Parkinson's disease and estimate its progression. source https://medicalxpress.com/news/2022-11-artificial-intelligence-gait-parkinson-disease.html

Researchers analyzing the data from MRI exams on nearly 8,000 children have identified biomarkers of attention-deficit/hyperactivity disorder (ADHD) and a possible role for neuroimaging machine learning to help with the diagnosis, treatment planning and surveillance of the disorder. The results of the new study will be presented next week at the annual meeting of the Radiological Society of North America (RSNA). source https://medicalxpress.com/news/2022-11-brain-markers-adhd-children.html

For the first time, a new study has identified enlarged perivascular spaces in the brains of migraine sufferers. Results of the study will be presented next week at the annual meeting of the Radiological Society of North America (RSNA). source https://medicalxpress.com/news/2022-11-ultra-high-resolution-mri-reveals-migraine-brain.html

Antimicrobials are medicines used to prevent and treat infections in humans, animals and plants. Antimicrobial resistance occurs when bacteria, viruses, fungi or parasites resist the effects of available antimicrobial medications. This makes it easier for infectious diseases to spread and to cause more severe illnesses and deaths. source https://medicalxpress.com/news/2022-11-world-antimicrobial-resistance.html

A happy holiday can go sour quickly when food poisoning joins the party. source https://medicalxpress.com/news/2022-11-food-poisoning-bay-holiday-season.html

Traveling to see family for the holidays can be a gut-wrenching experience for the approximately 15% of the population living with Irritable Bowel Syndrome (IBS). The stress—from families who do not accommodate or understand individual's dietary needs or stress arising from family conflicts—rachets up their anxiety and worsens symptoms. source https://medicalxpress.com/news/2022-11-people-ibs-stomach-holidays.html

Burnet Institute researchers have led the development of the first global strategic guidelines—called target product profiles (TPPs)—for medicines to prevent and treat preeclampsia, a hypertensive disorder in pregnancy that's one of the leading causes of maternal deaths, stillbirth, and preterm birth globally. source https://medicalxpress.com/news/2022-11-insights-medicines-preeclampsia.html

A new method for the miniaturization of biosensors will enable new possibilities for minimally invasive implants. The miniaturized transistors are fabricated on thin, flexible substrates, and amplify biosignals, producing currents more than 200 times larger than analogous alternatives. source https://medicalxpress.com/news/2022-11-miniaturized-biosensors-minimally-invasive-implants.html

The diminished power of the immune system in older adults is usually blamed on the aging process. But a new study by Columbia immunologists shows that decades of particulate air pollution also take a toll. source https://medicalxpress.com/news/2022-11-decades-air-pollution-undermine-immune.html

Talking to your doctor about drug costs could help you save on prescriptions. Learn what your doctor can do when you can't afford your medication. source https://www.webmd.com/health-insurance/features/drug-costs-speak-up?src=RSS_PUBLIC

Bacterial infections are the second leading cause of death worldwide, accounting for one in eight of all deaths in 2019, the first global estimate of their lethality revealed on Tuesday. source https://medicalxpress.com/news/2022-11-bacterial-infections-death-worldwide.html

A team of researchers at the University of Sydney working with a colleague from Shenzhen University School of Medicine has found that lab mice are more likely to survive a flu infection if they are fed grain-based foods rather than processed food. The paper is published in Cell Reports. source https://medicalxpress.com/news/2022-11-lab-mice-fed-food-fare.html

A team led by researchers from Tokyo Metropolitan University have identified the best methods to study the resting state of the brain in marmosets using functional MRI. Studies often use sedatives and anesthetics to limit movement during measurements, but the drugs themselves can affect brain activity. The team studied seven drugs and identified choices which preserved normal function while minimizing motion. Their work extends the scope of research into an important model organism. source https://medicalxpress.com/news/2022-11-scientists-optimize-methods-brains-rest.html

Researchers now have a unique resource for identifying new biomarkers of environmental exposures in early life and understanding their health effects. This is thanks to a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by la Caixa Foundation, which systematically documented all associations between a wide range of early life exposures and molecular profiles at different levels, including the epigenome (DNA methylation), transcriptome (gene expression) and metabolome (metabolites). source https://medicalxpress.com/news/2022-11-unique-resource-environmental-exposures-early.html

China reported two new deaths from COVID-19 on Monday, both elderly Beijing residents, as several major cities persisted with strict virus curbs despite a much-touted recent loosening. source https://medicalxpress.com/news/2022-11-china-covid-deaths-infections-surge.html

A new rapid phobia treatment for children and young people could help to reduce the impact on NHS and improve quality of life, a new study has found. source https://medicalxpress.com/news/2022-11-breakthrough-rapid-phobia-treatment-children.html

Scientists at the Garvan Institute of Medical Research have identified molecular profiles of the surrounding matrix of a common type of lung cancer that might indicate which patients are likely to develop aggressive tumors. source https://medicalxpress.com/news/2022-11-tumor-matrix-profiling-clues-lung.html

China on Sunday announced its first new death from COVID-19 in nearly half a year as strict new measures are imposed in Beijing and across the country to ward against new outbreaks. source https://medicalxpress.com/news/2022-11-china-1st-covid-death-months.html

A team of researchers affiliated with several entities in Thailand, working with two colleagues from the U.S. and two from Canada, has developed a mRNA COVID-19 vaccine that can be safely refrigerated for up to three months before use. The team has named it ChulaCov19. source https://medicalxpress.com/news/2022-11-covid-vaccine-thailand-refrigerator-months.html

An unusual type of antibody that even at miniscule levels neutralizes the Zika virus and renders the virus infection undetectable in preclinical models has been identified by a team led by Weill Cornell Medicine, New York-Presbyterian and National Institutes of Health (NIH) investigators. source https://medicalxpress.com/news/2022-11-unusual-antibody-ultrapotent-zika.html

Multiple studies that have found people with celiac disease face higher risks for diabetes, thyroid conditions, arthritis, and other autoimmune disorders. source https://www.webmd.com/digestive-disorders/celiac-disease/news/20221118/celiac-disease-may-lead-to-other-autoimmune-disorders?src=RSS_PUBLIC

Researchers at UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have grown "mini eyes," which make it possible to study and better understand the development of blindness in a rare genetic disease called Usher syndrome for the first time. source https://medicalxpress.com/news/2022-11-lab-grown-mini-eyes-rare.html

Mira Ugwuadu felt anxious and depressed when she returned to her high school in Cobb County, Georgia, last fall after months of remote learning, so she sought help. But her school counselor kept rescheduling their meetings because she had so many students to see. source https://medicalxpress.com/news/2022-11-schools-struggle-staff-youth-mental.html

A comprehensive genomic analysis in more than 200 patients with metastatic urothelial carcinomas may help inform how a patient would respond to immunotherapy, report UNC Lineberger Comprehensive Cancer Center researchers and colleagues. About 90% of urothelial carcinomas are bladder cancers. These results, derived from a computational model based on the initial molecular findings of the UC-GENOME study, are published in Nature Communications. source https://medicalxpress.com/news/2022-11-genetic-analysis-common-bladder-cancer.html

A Crohn’s disease researcher talks about the quest for a cure and better treatments. source https://www.webmd.com/ibd-crohns-disease/crohns-disease/features/crohns-cure?src=RSS_PUBLIC

Cancer that splits and develops in new organs around the body becomes significantly more difficult to fight. Now, researchers at Chalmers have shown that these metastatic cancers, that spread from the original, adapt their metabolism to the tissue in which they grow. The discovery represents a breakthrough for the understanding of metastatic cancer and is an important piece of the puzzle in the search for more effective treatments. source https://medicalxpress.com/news/2022-11-metastatic-cancers-metabolism-tissue.html

Rotting teeth, swollen gums and oral cancers: nearly half the world's population suffer from mouth diseases, the World Health Organization said Thursday. source https://medicalxpress.com/news/2022-11-mouth-diseases-world-people.html

The head of Africa's top public health institute is urging authorities across the continent to step up COVID-19 testing amid a concerning rise in new cases in some countries. source https://medicalxpress.com/news/2022-11-africa-cdc-chief-urges-covid-.html

U.S. home births increased slightly in the pandemic's second year, rising to the highest level in decades, according to a government report published Thursday. source https://medicalxpress.com/news/2022-11-home-births-pandemic-uncommon.html

A polymer-based microshunt is safe and effective in pediatric patients with refractory childhood glaucoma, according to a small, single-center case series at the UC Davis Health Eye Center. source https://medicalxpress.com/news/2022-11-uc-davis-health-microshunt-children.html

Learn about some of the latest tools you can use to manage your heart failure, from medical devices to apps and text messages. source https://www.webmd.com/features/new-tech-treatment?src=RSS_PUBLIC

HSE researchers have found genes characteristic of the most aggressive subtype of clear cell renal carcinoma. Having studied data on tumor samples from 456 patients, Grigory Puzanov, research fellow at the HSE Faculty of Computer Science International Laboratory of Bioinformatics, identified cancer subtypes associated with either a favorable or unfavorable course of the disease. The paper is published in Scientific Reports. source https://medicalxpress.com/news/2022-11-genes-aggressive-kidney-cancer.html

Research finds low-certainty evidence that programs such as emergency rent assistance, legal assistance with waitlist priority for public housing, long-term rent subsidies and homeownership assistance lead to positive health outcomes. source https://medicalxpress.com/news/2022-11-weak-evidence-interventions-boost-housing.html

Not all diabetes is the same, and it goes well beyond the two main classifications, type 1 and type 2. Monogenic diabetes refers to forms of diabetes caused by single genetic variations. Maturity-onset diabetes of the young (MODY) is the most common clinical subdivision of monogenic diabetes, with diabetes typically arising in young adulthood. source https://medicalxpress.com/news/2022-11-treatment-diabetes-greenland-discovery-widespread.html

The US drugs agency has approved a test by Swiss pharmaceutical giant Roche that can detect monkeypox, the company said on Wednesday. source https://medicalxpress.com/news/2022-11-monkeypox-swiss-giant-roche.html

Chinese authorities locked down a major university in Beijing on Wednesday after finding one COVID-19 case as they stick to a "zero-COVID" approach despite growing public discontent. source https://medicalxpress.com/news/2022-11-zero-covid-china-case-peking-university.html

Her ALS, also called Lou Gehrig’s disease, “has made it impossible to sing and not easy to speak,” manager Suzanne Koga said in a statement to the AP. “But it will take a lot more than ALS to silence this icon.” source https://www.webmd.com/brain/news/20221115/roberta-flack-has-als-can-no-longer-sing?src=RSS_PUBLIC

A non-small-cell lung cancer survivor and advocate shares the words that helped and hurt her the most. source https://www.webmd.com/lung-cancer/features/lung-cancer-advice?src=RSS_PUBLIC

In an analysis of more than 2,400 women, about 1 in 10 without a history of blood pressure issues were diagnosed with high blood pressure in the year after childbirth, according to a research article published today in Hypertension, an American Heart Association journal. Nearly a quarter of the women were diagnosed more than six weeks after delivery—a time when many women have stopped receiving follow-up care. source https://medicalxpress.com/news/2022-11-limited-postpartum-follow-up-high-blood.html

China's ruling party called for strict adherence to the hard-line "zero-COVID" policy Tuesday in an apparent attempt to guide public perceptions after regulations were eased slightly in places. source https://medicalxpress.com/news/2022-11-china-state-media-demands-strict.html

Nearly two-thirds (62%) of people with cancer want to know about complementary therapies such as exercise, nutrition counseling, massage, and meditation before starting conventional treatment, but only 33% of oncologists agree with that timeline, according to a new survey conducted on behalf of Samueli Foundation. source https://medicalxpress.com/news/2022-11-cancer-patients-access-complementary-therapies.html

Public Health authorities have warned health care workers to be on the alert for polio, yet most physicians will not be familiar with presentation of this highly infectious, life-threatening disease. source https://medicalxpress.com/news/2022-11-polio-disease.html

New study results from an international research team led by USC scientists have identified a signature pattern of white matter connectivity exclusive to the brains of autistic people distinct from that in the brains of people with developmental coordination disorder (DCD). source https://medicalxpress.com/news/2022-11-brain-regions-signature-autistic-individuals.html

To improve the health of a community, the first step is to identify its most pressing needs. To that end, in 2022 Hospital for Special Surgery (HSS) implemented a community-based participatory research (CBPR) approach to assess musculoskeletal health needs, identify health disparities and support the development of initiatives to address unmet needs. source https://medicalxpress.com/news/2022-11-chronic-pain-falls-limited-access-critical.html

Vulnerable populations in 45 high-burden countries worldwide must be prioritized in efforts to reduce the impact of the COVID-19 pandemic on tuberculosis (TB) care, according to new research published in BMC Medicine. source https://medicalxpress.com/news/2022-11-covid-catch-up-interventions-tb-vulnerable.html

After sun exposure, people with systemic lupus erythematosus (SLE) frequently develop skin rashes, which often are accompanied by a flare of their overall disease. This connection between ultraviolet (UV) light and disease flares in lupus is well known, but the way in which UV exposure actually triggers the disease has been poorly understood. source https://medicalxpress.com/news/2022-11-uncovers-uv-triggers-immune-disease.html

A new study from researchers at Hospital for Special Surgery (HSS) has evaluated trends in the use of total knee arthroplasty (TKA) in patients under 21 in the United States. The study was reported at the American College of Rheumatology (ACR) Convergence 2022 meeting (abstract number 08780). source https://medicalxpress.com/news/2022-11-total-knee-patients.html

Personalized care has been a buzzword in medicine for years, but new research on cancer treatment is taking it to a new level. source https://medicalxpress.com/news/2022-11-cancer-therapy-personalized-medicine.html

People who have had COVID more than once are two or three times more likely to have a range of serious health problems than those who have only had it once, the first major study on the subject said Thursday. source https://medicalxpress.com/news/2022-11-covid-infections-health-problems.html

A study at Hospital for Special Surgery (HSS) highlights the success of a lupus peer support and education group that transitioned to a virtual format during the pandemic. In addition to receiving high marks from group members, participation more than doubled after the meetings went remote. source https://medicalxpress.com/news/2022-11-lupus-group-hss-transitions-virtual.html

A toddler is thriving after doctors in the U.S. and Canada used a novel technique to treat her before she was born for a rare genetic disease that caused the deaths of two of her sisters. source https://medicalxpress.com/news/2022-11-doctors-fatal-genetic-disease-birth.html

Everyone in a district of 1.8 million people in China's southern metropolis of Guangzhou was ordered to stay home Saturday to undergo virus testing and a major city in the southwest closed schools as another rise in infections was reported. source https://medicalxpress.com/news/2022-11-china-tightens-restrictions-virus-cases.html

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phase 2 clinical trial published in Arthritis & Rheumatology has generated promising results for deucravacitinib, an oral inhibitor of tyrosine kinase 2 (TYK2), in patients with active lupus. source https://medicalxpress.com/news/2022-11-oral-deucravacitinib-benefits-patients-lupus.html

Fluorescence microscopy allows researchers to study specific structures in complex biological samples. However, the image created using fluorescent probes suffers from blurring and background noise. The latest work from NIBIB researchers and their collaborators introduces several novel image restoration strategies that create sharp images with significantly reduced processing time and computing power. The research is published in Nature Methods. source https://medicalxpress.com/news/2022-11-neural-networks-physics-based-faster-clearer.html

Using high-throughput genome sequencing and machine learning, scientists at UMass Chan Medical School have shown a strong correlation between the oral microbiome in patients with COVID-19 at the time of hospital admission and the need for later respiratory support. Published in Frontiers in Microbiology, the study adds to a growing body of research linking the oral microbiome with respiratory illnesses and offers new insights into how SARS-CoV-2 impacts inflammation and causes disease. source https://medicalxpress.com/news/2022-11-evidence-link-oral-microbiome-covid.html

A new study shows that when an experimental cancer medication is split in half, the molecule becomes safer and more effective. source https://medicalxpress.com/news/2022-11-cancer-drug.html

A new Harvey L. Neiman Health Policy Institute study found when patients are treated in the Emergency Department (ED) by non-physician practitioners (physicians assistants and nurse practitioners), there were 5.3% more imaging studies performed than if patients were seen only by physicians. This JAMA Network Open study was based on a nationally representative sample of Medicare fee-for-service beneficiaries with 16,922,274 ED visits between 2005 and 2020. source https://medicalxpress.com/news/2022-11-non-physician-practitioners-ed-imaging.html

China announced the relaxation of some of its hardline COVID-19 restrictions on Friday, after authorities had vowed to stick to a zero-tolerance virus approach despite mounting economic damage. source https://medicalxpress.com/news/2022-11-china-eases-covid-quarantine-scrapping.html

The lifting of masking requirements in school districts outside of Boston in February 2022 was associated with an additional 44.9 COVID-19 cases per 1,000 students and staff in the 15 weeks after the statewide masking policy was rescinded. This represented nearly 12,000 total COVID-19 cases or 30% of all cases in those school districts that unmasked during that time, according to a new study led by Harvard T.H. Chan School of Public Health, the Boston Public Health Commission, and Boston University School of Public Health. source https://medicalxpress.com/news/2022-11-masking-requirements-boston-schools-students.html

China's capital Beijing has closed city parks and imposed other restrictions as the country faces a new wave of COVID-19 cases. source https://medicalxpress.com/news/2022-11-china-virus-cases-capital.html

In a multi-year research program coordinated by the two directors of .NeuroRestore—Grégoire Courtine, a neuroscience professor at EPFL, and Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital (CHUV)—patients who had been paralyzed by a spinal cord injury and who underwent targeted epidural electrical stimulation of the area that controls leg movement were able to regain some motor function. source https://medicalxpress.com/news/2022-11-scientists-neurons-paralysis.html

Is exercising good for pulmonary hypertension? Find out how moving your body can benefit your condition. source https://www.webmd.com/lung/features/pah-exercise?src=RSS_PUBLIC

You can still enjoy your life, even with pulmonary hypertension. Diagnosed 12 years ago, Nicole Creech shares her story. source https://www.webmd.com/lung/features/pah-full-life?src=RSS_PUBLIC

In the U.S., dialysis is a costly treatment with poor health outcomes. According to the Centers for Disease Control and Prevention, 15% of adults—37 million people—have chronic kidney disease. As the disease progresses to end-stage kidney disease, patients are required to receive dialysis regularly or have a kidney transplant. Although dialysis is lifesaving in the short-term, five-year mortality rates exceed 60%. source https://medicalxpress.com/news/2022-11-dialysis-delivery-ways-patient-outcomes.html

Using a protocol developed at UC San Francisco, physicians have successfully treated a fetus with a devastating genetic disorder for the first time, and the child is now thriving as a toddler, a case study in the New England Journal of Medicine reports. source https://medicalxpress.com/news/2022-11-rare-deadly-genetic-disease-successfully.html

A thermal-imaging tool to screen for chronic wounds could enable nurses to identify these hard-to-heal sores during the first assessment at a person's home. source https://medicalxpress.com/news/2022-11-contactless-screening-tool-revolutionize-chronic.html

An advanced radiotherapy technique can be used to safely treat prostate cancer patients in as little as one to two weeks, compared with the current standard, which takes one to two months. source https://medicalxpress.com/news/2022-11-advanced-radiotherapy-safely-prostate-cancer.html

In Alzheimer's disease, the degeneration of brain cells is linked to formation of toxic protein aggregates and deposits known as amyloid plaques. Similar processes also play an important role in type 2 diabetes. A research team under the lead of the Technical University of Munich has now developed "mini-proteins," so-called peptides, which are able to bind the proteins that form amyloids and prevent their aggregation into cytotoxic amyloids. source https://medicalxpress.com/news/2022-11-alzheimer-disease-diabetes-synthetic-peptides.html

A team of medical professionals, clinicians, epidemiologists and political scientists recently published the results of a study that revealed new information about the prevalence of post-acute sequelae of SARS CoV-2 infection, otherwise known as "long COVID." source https://medicalxpress.com/news/2022-11-women-higher-covid.html

A recent study in Developmental Medicine & Child Neurology has linked exposure to tiny particles of air pollution—called fine particulate matter—during pregnancy to delays in children's gross motor, fine motor, and personal–social development. source https://medicalxpress.com/news/2022-11-air-pollution-pregnancy-affect-child.html

An analysis in the Journal of the American Geriatrics Society found that between 2015 and 2019, an increasing proportion of US nursing home residents with Alzheimer's Disease and related dementias (ADRD) were prescribed antiepileptics, while antipsychotic and opioid prescribing rates declined. source https://medicalxpress.com/news/2022-11-trends-antiepileptic-antipsychotic-opioid-nursing.html

Uganda will close schools nationwide later this month after 23 Ebola cases were confirmed among pupils, including eight children who died, the country's first lady said on Tuesday. source https://medicalxpress.com/news/2022-11-uganda-schools-children-die-ebola.html

A year-long study of the dietary habits of 9,341 Australians has backed growing evidence that highly processed and refined foods are the leading contributor of rising obesity rates in the Western world. source https://medicalxpress.com/news/2022-11-foods-key-obesity.html

A new drug called Baxdrostat has been shown to significantly reduce high blood pressure (hypertension) in patients who may not respond to current treatments for the condition, according to results from a phase II trial led jointly by a Queen Mary University of London researcher and colleagues at CinCor Pharma, U.S.. source https://medicalxpress.com/news/2022-11-drug-successfully-patients-typically-resistant.html

Besides feeling sluggish, people may be hungrier, crave carbohydrates, eat more and gain weight. They may also feel less motivated and find less enjoyment in activities. source https://www.webmd.com/depression/news/20221107/sad-season-depression-risks-rise-as-days-get-shorter?src=RSS_PUBLIC

Researchers have discovered the vital role of a hormone, which develops in men during puberty, in providing an early prediction of whether they could develop certain diseases in later life. source https://medicalxpress.com/news/2022-11-hormone-discovery-long-term-health-men.html

Lipoprotein(a) is a special type of bad cholesterol that is believed to contribute to heart disease, but there are no approved pharmacological therapies to decrease its concentration in the bloodstream. Olpasiran is an investigational drug that reduces lipoprotein(a) concentration by degrading the RNA that codes for a protein that is an essential part of the molecule. source https://medicalxpress.com/news/2022-11-clinical-trial-therapy-markedly-lipoproteina.html

A genetic test known as chromosomal microarray analysis (CMA) could help identify the cause of sudden infant death syndrome (SIDS) or its counterpart in older children, known as sudden unexplained death in childhood (SUDC), finds a study led by Boston Children's Hospital. source https://medicalxpress.com/news/2022-11-chromosomal-options-exploring-sids.html

Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers. source https://medicalxpress.com/news/2022-11-personalising-genome-sequencing-diagnosis-rare.html

Some cancer cells can deploy parallel mechanisms to evade the immune system's defenses as well as resist immunotherapy treatment, according to a new study from the Garvan Institute of Medical Research. source https://medicalxpress.com/news/2022-11-dna-barcoding-reveals-cancer-cells.html

Eczema—atopic dermatitis—is common in babies and can be stressful for parents to manage. An article in CMAJ (Canadian Medical Association Journal) outlines practical tips to manage this condition. source https://medicalxpress.com/news/2022-11-eczema-babies.html

China reported its highest daily COVID caseload in six months Monday, despite grinding lockdowns that have heavily disrupted manufacturing, education and day-to-day life. source https://medicalxpress.com/news/2022-11-china-virus-cases-six-month-high.html

Ultraprocessed foods (UPFs), ready-to-eat-or-heat industrial formulations made with ingredients extracted from foods or synthesized in laboratories, have gradually been replacing traditional foods and meals made from fresh and minimally processed ingredients in many countries. A new study in the American Journal of Preventive Medicine has found that increased consumption of these foods was associated with more than 10% of all-cause premature, preventable deaths in Brazil in 2019, although Brazilians consume far less of these products than countries with high incomes. source https://medicalxpress.com/news/2022-11-ultraprocessed-foods-linked-premature-deaths.html

People with monkeypox can spread the virus up to four days before symptoms appear, with more than half of transmissions potentially taking place during this period, a UK study estimated Tuesday. source https://medicalxpress.com/news/2022-11-monkeypox-symptoms.html

Chinese health officials gave no indication Saturday of any relaxation of COVID-19 restrictions, following several days of speculation that the government was considering changes to a "zero-COVID" approach that has stymied economic growth and disrupted daily life. source https://medicalxpress.com/news/2022-11-chinese-zero-covid-policy.html

The psychedelic chemical in "magic mushrooms" may ease depression in some hard-to-treat patients, a preliminary study found. source https://medicalxpress.com/news/2022-11-psychedelic-magic-mushroom-drug-ease.html