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Showing posts from September, 2022

Some officials now say monkeypox elimination unlikely in US

Some U.S. health officials are conceding that monkeypox is probably not going away anytime soon. source https://medicalxpress.com/news/2022-10-monkeypox.html

US suicide rate rose in 2021 after falling for two years

The US suicide rate rose in 2021, particularly among young men, according to official data out Friday—an increase that ends a two-year-decline. source https://medicalxpress.com/news/2022-10-suicide-rose-falling-years.html

Abortion info fight targets university but affects far more

A box truck equipped with a bright LED billboard began circling around the University of Idaho campus Friday. source https://medicalxpress.com/news/2022-10-abortion-info-university-affects.html

Better Asthma and COPD Drugs with Fewer Side Effects Are Within Reach

Bronchodilators, the most common type of asthma-fighting drug, inhibits contractions of airway smooth muscle that are induced by stimulating receptors on the muscle's surface. New research highlights a novel mechanism for the drugs and will aid in the development of better medications for the treatment of asthma and chronic obstructive pulmonary disease (COPD). The findings are detailed in a new article by researchers from Dundalk Institute of Technology in Ireland and Queen's University in Northern Ireland. source https://medicalxpress.com/news/2022-10-asthma-copd-drugs-side-effects.html

Study advances knowledge of role of brain pathology and cognitive fatigue in multiple sclerosis

Using advanced diffusion neuroimaging technology, Kessler Foundation researchers investigated the relationship between the rate of cognitive fatigue to microstructural changes in the brain in persons with multiple sclerosis. Their findings help fill a gap in the current understanding of how brain pathology influences the development of fatigue over time. source https://medicalxpress.com/news/2022-10-advances-knowledge-role-brain-pathology.html

Indonesia approves first homegrown Covid-19 vaccine

Indonesia has approved its first locally developed Covid-19 vaccine for emergency use, the head of the country's public health agency said Friday, hailing it as a step toward "the nation's independence in access to medicine". source https://medicalxpress.com/news/2022-09-indonesia-homegrown-covid-vaccine.html

Gut bacteria may contribute to susceptibility to HIV infection, research suggests

New UCLA-led research suggests certain gut bacteria—including one that is essential for a healthy gut microbiome—differ between people who go on to acquire HIV infection compared to those who have not become infected. source https://medicalxpress.com/news/2022-09-gut-bacteria-contribute-susceptibility-hiv.html

Reversing lung fibrosis in scleroderma requires an increase in antifibrotic proteins

Much of the research on scleroderma, a connective tissue disease that causes scarring, or fibrosis, has focused on the increased number of proteins promoting fibrosis in these patients. A Medical University of South Carolina (MUSC) research team took a different tact and measured the levels of an antifibrotic protein, Cathepsin L, in these patients. They report in Rheumatology that patients with scleroderma had reduced levels of this antifibrotic protein, and the Cathepsin L that they did have was packaged in an inactive state that deprived it of its antifibrotic function. The team was led by Carol Feghali-Bostwick, Ph.D., the Kitty Trask Holt Endowed Chair for Scleroderma Research, and M.D.-Ph.D. student Joe Mouawad, a National Scleroderma Foundation predoctoral fellowship awardee. source https://medicalxpress.com/news/2022-09-reversing-lung-fibrosis-scleroderma-requires.html

Ensuring diverse participation in Alzheimer's clinical trial participants

Enrolling representative populations in clinical trials for Alzheimer's disease is critical for finding treatments that will be safe and effective for all patients. African Americans and Latinos are disproportionately affected by this disease yet are substantially underrepresented in trials of promising therapies. For example, an analysis of data from more than 100 clinical trials testing new treatments for Alzheimer's disease found that only 12% of participants were of any non-White race or Hispanic ethnicity. source https://medicalxpress.com/news/2022-09-diverse-alzheimer-clinical-trial.html

Race and ethnicity influence end-of-life care for Medicare patients with dementia

Researchers have known that race and ethnicity play a role in the intensity of medical care at the end of life, but the difference is more pronounced among individuals with dementia, the researchers found. source https://medicalxpress.com/news/2022-09-ethnicity-end-of-life-medicare-patients-dementia.html

Researchers create new method to more accurately measure cancer lesions response to treatment

Researchers from the University of Colorado Cancer Center on the Anschutz Medical Campus have created a new way of measuring cancer lesions response to treatment that could better inform the development of new cancer drugs. source https://medicalxpress.com/news/2022-09-method-accurately-cancer-lesions-response.html

Acute respiratory illness due to EV-D68 increased in late summer 2022

In late summer 2022, for children and adolescents, there was an increase in acute respiratory illness (ARI) resulting from enterovirus (EV)-D68 in the United States, according to research published in the Sept. 27 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. source https://medicalxpress.com/news/2022-09-acute-respiratory-illness-due-ev-d68.html

New study highlights sexual problems for young women who've had cancer

Young women cancer survivors are at much higher risk of sexual problems, including loss of libido and discomfort, according to research published in the peer-reviewed journal Acta Oncologica. source https://medicalxpress.com/news/2022-09-highlights-sexual-problems-young-women.html

How deadly brain cancer evades treatments

McMaster University researcher Sheila Singh and her team have discovered how glioblastoma, a lethal brain cancer, can evade treatments and kill. source https://medicalxpress.com/news/2022-09-deadly-brain-cancer-evades-treatments.html

Surface mapping a reliable diagnostic tool for gut health

Non-invasive sensors laid on the skin's surface to measure bioelectrical activity could offer a better alternative for patients suffering with poor gut health. source https://medicalxpress.com/news/2022-09-surface-reliable-diagnostic-tool-gut.html

Next-generation liquid biopsy detects nano-sized signs of breast cancer in early-stage patients

A USC-led team of scientists has found indications that a special blood test called a liquid biopsy could determine whether a patient has breast cancer at its early stage and if that cancer is unlikely to return. source https://medicalxpress.com/news/2022-09-next-generation-liquid-biopsy-nano-sized-breast.html

Study finds folic acid treatment is associated with decreased risk of suicide attempts

Suicide is one of the leading causes of death in the US, with more than 45,000 people dying by suicide in 2020. Experts recommend many strategies and treatments to decrease the risk of suicide, including psychotherapy, peer support, economic support, and medications like antidepressants. Few if any would be likely to put folic acid supplements on that list, but a recent study done at the University of Chicago may change that. source https://medicalxpress.com/news/2022-09-folic-acid-treatment-decreased-suicide.html

Exposure to air pollution worsens COVID-19 outcomes, even among the fully vaccinated

COVID-19 is a respiratory illness, so it's not surprising that exposure to poor air quality worsens patient outcomes. But how does air pollution affect people who are vaccinated? source https://medicalxpress.com/news/2022-09-exposure-air-pollution-worsens-covid-.html

Skin whitening products remain popular in Cameroon despite risks

Wearing a large hat protecting her face from the sun's rays in Cameroon, 63-year-old Jeanne now bitterly regrets using skin whitening products after being diagnosed with skin cancer. source https://medicalxpress.com/news/2022-09-skin-whitening-products-popular-cameroon.html

Clinical trial shows bionic pancreas improves type 1 diabetes management compared to standard insulin delivery method

A device known as a bionic pancreas, which uses next-generation technology to automatically deliver insulin, was more effective at maintaining blood glucose (sugar) levels within normal range than standard-of-care management among people with type 1 diabetes, a new multicenter clinical trial has found. The trial, conducted partly at Nemours Children's Health, Jacksonville, was published in the New England Journal of Medicine. source https://medicalxpress.com/news/2022-09-clinical-trial-bionic-pancreas-diabetes.html

Neurology: Early treatment is half the battle

Neurological diseases often begin with an inflammatory process and the degradation of the myelin layer, which surrounds the nerve fibers (axons) like a protective insulating layer. This is usually followed by damage to the nerve fibers (axonal neurodegeneration). The clock is now ticking: while the inflammatory process is still easily treatable in the early stages of neurological conditions, the relevant therapies are often no longer effective enough in the later stages. source https://medicalxpress.com/news/2022-09-neurology-early-treatment.html

Saliva test could provide early warning for severe COVID cases

Saliva samples could soon be key to predicting the severity of someone's case of COVID-19, allowing hospitals to triage patients effectively, according to new research from the University of Surrey. source https://medicalxpress.com/news/2022-09-saliva-early-severe-covid-cases.html

Omega-3 fatty acids, and in particular DHA, are associated with increased attention scores in adolescents

Docosahexaenoic acid (DHA) is associated with a greater capacity for selective and sustained attention in adolescents, while alpha-linolenic acid (ALA) is associated with lower impulsivity, according to a study co-led by ISGlobal, a center supported by the "la Caixa" Foundation and the Pere Virgili Institute for Health Research (ISPV). The results, published in European Child & Adolescent Psychiatry, confirm the importance of having a diet that provides sufficient amounts of these polyunsaturated fatty acids for a healthy brain development. source https://medicalxpress.com/news/2022-09-omega-fatty-acids-dha-attention.html

Organ-on-a-chip study reveals mechanism of SARS-CoV-2 invasion into blood vessels

A research group led by CiRA Junior Associate Professor Kazuo Takayama and Associate Professor Yoshiaki Okada of Osaka University has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels. source https://medicalxpress.com/news/2022-09-organ-on-a-chip-reveals-mechanism-sars-cov-invasion.html

Increased risk of cancer in children born to mothers with epilepsy using high-dose folic acid during pregnancy

High-dose folic acid is protective against congenital malformations if the mother is at particular risk of having a child with congenital malformations. Treatment with antiseizure medication in pregnancy is associated with risk of congenital malformations in the children, and women with epilepsy are therefore often recommended a supplementary high dose of folic acid (4–5 mg daily) before and during pregnancy. However, some studies have raised concern that folic acid can increase the risk of cancer not only in the mother, but in the child when exposed during pregnancy. source https://medicalxpress.com/news/2022-09-cancer-children-born-mothers-epilepsy.html

UN urges action as mental health takes heavy toll on workers

Far more must be done to safeguard mental health on the job, the United Nations said Wednesday, presenting new guidelines on how to lessen psychological strains linked to the workplace. source https://medicalxpress.com/news/2022-09-urges-action-mental-health-heavy.html

Scientists studying fatal muscle wasting disease make significant discovery

Duchenne muscular dystrophy (DMD) is caused by a genetic mutation and affects one in every 5,000 boys born. Because the affected gene is on the X chromosome, girls are carriers of the mutant gene but develop the disease only very rarely (one in about 50 million). source https://medicalxpress.com/news/2022-09-scientists-fatal-muscle-disease-significant.html

Language learning difficulties in children linked to brain differences

Developmental language disorder (DLD) is an extremely common disorder, affecting approximately two children in every classroom. Children with DLD struggle to comprehend and use their native language, facing trouble with grammar, vocabulary, and holding conversations. Their language difficulties considerably increase the risk of having difficulties when learning to read, underachieving academically, being unemployed, and facing social and mental health challenges. source https://medicalxpress.com/news/2022-09-language-difficulties-children-linked-brain.html

Study finds different comorbidities have different impacts on COVID outcomes

A new paper in Biology Methods & Protocols, published by Oxford University Press, indicates that some pre-existing conditions—including degenerative neurological diseases, dementia, and severe disabilities—matter a lot more than once thought when assessing who is at risk for death due to COVID-19. source https://medicalxpress.com/news/2022-09-comorbidities-impacts-covid-outcomes.html

Being lonely and unhappy accelerates aging more than smoking, study finds

Molecular damage accumulates and contributes to the development of aging-related frailty and serious diseases. In some people these molecular processes are more intense than in others, a condition commonly referred to as accelerated aging. source https://medicalxpress.com/news/2022-09-lonely-unhappy-aging.html

Pfizer seeks to expand omicron booster to 5- to 11-year-olds

Pfizer asked U.S. regulators Monday to expand use of its updated COVID-19 booster shot to children ages 5 to 11. source https://medicalxpress.com/news/2022-09-pfizer-omicron-booster-year-olds.html

Canada announces end to Covid border restrictions

Canada will suspend Covid-19 border restrictions in October, the country's public health agency said Monday. source https://medicalxpress.com/news/2022-09-canada-covid-border-restrictions.html

Fecal transplantation: An effective remedy for life-threatening intestinal infections

Fecal transplantation in the intestine is an effective cure—and far superior to today's standard treatment—for a life-threatening infection that affects between 2,500 and 3,000 people in Denmark every year. source https://medicalxpress.com/news/2022-09-fecal-transplantation-effective-remedy-life-threatening.html

'Placenta-on-a-chip' mimics malaria-infected nutrient exchange between mother and fetus

Placental malaria as a consequence of Plasmodium falciparum infections can lead to severe complications for both mother and child. Each year, placental malaria causes nearly 200,000 newborn deaths, mainly due to low birth weight, as well as 10,000 maternal deaths. Placental malaria results from parasite-infected red blood cells that get stuck within tree-like branch structures that make up the placenta. source https://medicalxpress.com/news/2022-09-placenta-on-a-chip-mimics-malaria-infected-nutrient-exchange.html

Flow velocity in the gut regulates nutrient absorption and bacterial growth

The flow velocity in our digestive system directly determines how well nutrients are absorbed by the intestine and how many bacteria live inside it. This is the result of a new study by researchers from the Technical University of Munich (TUM) and the Max Planck Institute for Dynamics and Self-Organization (MPI-DS). The researchers revealed the physics mechanisms of how the intestine can regulate itself to optimize nutrient absorption while limiting unwanted bacterial growth at the same time. source https://medicalxpress.com/news/2022-09-velocity-gut-nutrient-absorption-bacterial.html

Pediatric early warning systems for children with cancer a success in Latin American Hospitals

Pediatric Early Warning Systems (PEWS)—bedside tools used by nurses to assess the health of hospitalized children and identify urgent medical issues—are not widely used in resource-limited hospitals, in part due to challenges with implementation. A recent article published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, reports on a successful collaboration to support implementation of a PEWS for children with cancer in Latin American hospitals. source https://medicalxpress.com/news/2022-09-pediatric-early-children-cancer-success.html

Collaborative home-based palliative care model helps people die at home rather than hospital

Patients with chronic heart failure who received collaborative, home-based palliative care were less likely to die in hospital and more likely to die at home than people who received usual care, according to new research in Canadian Medical Association Journal (CMAJ). source https://medicalxpress.com/news/2022-09-collaborative-home-based-palliative-people-die.html

Hospitals treat thousands of drug-related bike injuries each year

From 2019 to 2020, more than 11,000 people who had been using drugs were treated in U.S. emergency departments for injuries that occurred while riding a bicycle, according to a new report in the Journal of Studies on Alcohol and Drugs. source https://medicalxpress.com/news/2022-09-hospitals-thousands-drug-related-bike-injuries.html

Babies in the womb react differently to flavours: researchers

Babies in the womb are big fans of carrots but not so much leafy green vegetables—and show it in their faces, scientists said in a new study published Thursday. source https://medicalxpress.com/news/2022-09-babies-womb-react-differently-flavours.html

Disarming the immune system's lethal lung response

Neutrophils, the most abundant type of white blood cell, are the body's first line of defense against infection. Foreign pathogens can stress the body and activate neutrophils. When activated, neutrophils employ various weapons to protect the body. But if overactivated, these weapons can damage the body's own tissues. Lung tissue is saturated with blood vessels, making them very susceptible to neutrophil attacks. If severe enough, acute lung injuries can lead to acute respiratory distress syndrome (ARDS), the leading cause of death due to COVID-19. source https://medicalxpress.com/news/2022-09-immune-lethal-lung-response.html

Do synchronized brains predict happy marriages?

When it comes to love, do opposites attract or do birds of a feather flock together? Surprisingly, the scientific research on romantic compatibility has produced conflicting results, with some studies suggesting that similarities in personality, demographics and attractiveness predict happily ever after, and others suggesting it's the differences that sustain a relationship. source https://medicalxpress.com/news/2022-09-synchronized-brains-happy-marriages.html

Friend or foe? How mice decide to make love or war

Dog owners whose pets meet during a walk are familiar with the immediate sniffing investigation that typically ensues. Initially, the owners cannot tell whether their dogs will wind up fighting, playing, or trying to mount each other. Something is clearly happening in the dog's brain to make it decide how to behave toward the other dog—but what is going on? source https://medicalxpress.com/news/2022-09-friend-foe-mice-war.html

Fourth SARS-CoV-2 vaccination also protects cancer patients

A research team led by Matthias Preusser from MedUni Vienna's Division of Oncology had already demonstrated that cancer patients benefit from a third vaccination to protect them against COVID. A recent study now also supports fourth vaccination for this vulnerable group. However, passive immunization by administering an antibody combination to cancer patients does not seem to provide adequate protection. The study has now been published in the journal JAMA Oncology. source https://medicalxpress.com/news/2022-09-fourth-sars-cov-vaccination-cancer-patients.html

Are Transgender People at Risk of Breast Cancer?

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Breast cancer can happen in people of any gender. Learn about what factors affect breast cancer risk in transgender people. source https://www.webmd.com/breast-cancer/features/breast-cancer-risk-transgender-people?src=RSS_PUBLIC

4.4M Americans roll up sleeves for omicron-targeted boosters

U.S. health officials say 4.4 million Americans have rolled up their sleeves for the updated COVID-19 booster shot. The Centers for Disease Control and Prevention posted the count Thursday as public health experts bemoaned President Joe Biden's recent remark that "the pandemic is over." source https://medicalxpress.com/news/2022-09-44m-americans-sleeves-omicron-targeted-boosters.html

Transition to newer clot-busting drug improves patient outcomes, lowers cost in treating ischemic stroke

A newer-generation clot-busting drug called tenecteplase outperforms the traditional treatment for ischemic strokes in several key areas, including better health outcomes and lower costs, according to a new study published today in the American Stroke Association's journal Stroke. source https://medicalxpress.com/news/2022-09-transition-clot-busting-drug-patient-outcomes.html

Acquired immunity to random food allergens may protect some lucky people against COVID-19

Why do some people become seriously ill with COVID-19, while others have no symptoms at all? The answer may lie in the proteins our immune system has previously been exposed to. source https://medicalxpress.com/news/2022-09-immunity-random-food-allergens-lucky.html

Drug treatment admissions fell sharply during first year of COVID-19 pandemic

Admissions to drug treatment programs declined by nearly one-quarter during the first year of the COVID-19 pandemic, with the cuts steepest among people of color, according to a new RAND Corporation study. source https://medicalxpress.com/news/2022-09-drug-treatment-admissions-fell-sharply.html

COVID-19 infections increase risk of long-term brain problems

If you've had COVID-19, it may still be messing with your brain. Those who have been infected with the virus are at increased risk of developing a range of neurological conditions in the first year after the infection, new research shows. Such complications include strokes, cognitive and memory problems, depression, anxiety and migraine headaches, according to a comprehensive analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system. source https://medicalxpress.com/news/2022-09-covid-infections-long-term-brain-problems.html

New imaging technique could speed up development of eye disease treatments

Researchers have developed a simple and fast way to perform optoretinography, an imaging technique that measures light-induced functional activity in the eye's retina, the network of neurons in the back of our eyes responsible for detecting light and initiating vision. More than 50% of people in the U.S. over age 60 are affected by retinal diseases such as macular degeneration and diabetic retinopathy. These diseases affect the retina's function in ways that reduce eyesight and can progress to blindness if not treated. The new approach could help accelerate the development of new treatments for eye diseases. source https://medicalxpress.com/news/2022-09-imaging-technique-eye-disease-treatments.html

Quick test kit to determine a person's immunity against COVID-19 and its variants

A team of scientists from the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, and Nanyang Technological University, Singapore (NTU Singapore) has developed a quick test kit that can tell if a person has immunity against COVID-19 and its variants, based on the antibodies detected in a blood sample. source https://medicalxpress.com/news/2022-09-quick-kit-person-immunity-covid-.html

Delayed intervention makes eliminating monkeypox more difficult

Vaccinations and lifestyle adjustments in at risk-populations have enabled public health authorities to gradually get a better handle on monkeypox in the U.S. However, a new study warns that it's too soon to relax. source https://medicalxpress.com/news/2022-09-intervention-monkeypox-difficult.html

New discovery suggests a novel strategy against harmful inflammation

A team led by Scripps Research scientists has uncovered key details of an immune cell process that frequently underlies excessive inflammation in the body. The findings could lead to new ways of preventing and/or treating inflammation-related conditions such as sepsis, arthritis, and coronary artery disease. source https://medicalxpress.com/news/2022-09-discovery-strategy-inflammation.html

FDA Admits Flaws in Response to Infant Formula Shortage

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Among the problems highlighted in the report were outdated data-sharing systems, while staffing and training for food inspectors was below normal. source https://www.webmd.com/parenting/baby/news/20220921/fda-admits-flaws-in-response-to-infant-formula-shortage?src=RSS_PUBLIC

SARS-CoV-2 mimics could accelerate vaccine research, make it safer

Though well-known as a respiratory illness, COVID-19 can also affect the nervous system, bringing on headaches and fatigue and wiping out the sense of smell. But it's unclear whether these symptoms are caused by an immune response or the virus itself invading the central nervous system (CNS). Now, researchers reporting in ACS Infectious Diseases have developed a new tool and possible vaccine candidate that could help scientists understand how SARS-CoV-2 could be invading these cells. source https://medicalxpress.com/news/2022-09-sars-cov-mimics-vaccine-safer.html

Does Skin Tone Affect Skin Care?

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Should your skin tone affect your daily skin care routine? Find out what dermatologists say. source https://www.webmd.com/skin-problems-and-treatments/features/skin-tones-skin-types?src=RSS_PUBLIC

New research identifies which countries may be better positioned to accept a 'new normal' of living with COVID-19

With the eradication of COVID-19 out of reach, are we close to a "new normal" in which we can leave restrictive non-pharmaceutical interventions (NPIs) behind—such as masks and social distancing—while simultaneously limiting the burden of disease and deaths? According to researchers at MIT Sloan School of Management, the answer depends on the ongoing risks versus communities' tolerance for those risks. source https://medicalxpress.com/news/2022-09-countries-positioned-covid-.html

Looking at images of people smiling at you extends the antidepressant effects of ketamine

Simple computer-based neurocognitive training—using positive words and pictures designed to boost self-worth—prolongs the antidepressant effects of ketamine in people with treatment-resistant depression, University of Pittsburgh researchers report today in the American Journal of Psychiatry. source https://medicalxpress.com/news/2022-09-images-people-antidepressant-effects-ketamine.html

American adolescent substance abuse—except for cannabis and vaping—has declined

Substance abuse among American adolescents is diminishing, except for an uptake in cannabis and vaping use—show new findings published today in the peer-reviewed journal Substance Use & Misuse. source https://medicalxpress.com/news/2022-09-american-adolescent-substance-abuseexcept-cannabis.html

Most CVD-related PROMs fall short of quality standards needed to guide clinical research and practice

A systematic review of patient-reported outcome measures (PROMs) used in cardiovascular disease (CVD) populations has found that most fall short of quality standards required to guide clinical research and practice. Few measurements reported on the validation of all Food and Drug Administration (FDA)-recommended psychometric properties, had psychometric properties rated as sufficient by Consensus-based Standards for the selection of health Measurement Instruments (COSMIN), or had minimally important differences established. The review is published in Annals of Internal Medicine. source https://medicalxpress.com/news/2022-09-cvd-related-proms-fall-short-quality.html

Finding new drugs to fight malaria

Malaria is an infection of red blood cells and is caused by parasites that are transferred to humans by mosquitoes. If left untreated, it can be fatal. In 2020 alone, nearly half the globe's population was at risk of being infected, with an estimated 241 million cases of malaria worldwide. source https://medicalxpress.com/news/2022-09-drugs-malaria.html

The 4-7-8 Breathing Technique May Help You Get to Sleep

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The 4-7-8 breathing technique can give people the opportunity to be at peace as a way to help them go to sleep. source https://www.webmd.com/a-to-z-guides/news/20220919/the-breathing-technique-may-help-you-get-to-sleep?src=RSS_PUBLIC

The Ebola virus: profile of a dreaded killer

The highly contagious Ebola virus has claimed more than 15,000 lives since it was first identified in central Africa in 1976. source https://medicalxpress.com/news/2022-09-ebola-virus-profile-dreaded-killer.html

New study explains the link between diabetes and urinary tract infections

Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden now show that the immune systems of people with diabetes have lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder's cell barrier, increasing the risk of urinary tract infection. The study is published in Nature Communications. source https://medicalxpress.com/news/2022-09-link-diabetes-urinary-tract-infections.html

Stress granules may drive obesity-associated pancreatic cancer

Obesity is a known risk factor for at least 13 types of cancer, in part because it creates ever-present inflammatory state. For years, one researcher has wondered if there's more to the story than inflammation. New research from the lab of Dr. Elda Grabocka shows a new way that obesity may drive cancer formation in pancreatic cancer, which has a five-year survival of 11% for the majority of patients. In a study published in Cancer Discovery, the researchers found that stress granules are much more abundant in obesity-related pancreatic cancer compared to non-obese patients, and importantly, blocking their formation stopped cancer growth in animals. The research reveals a new direction for developing cancer therapy. source https://medicalxpress.com/news/2022-09-stress-granules-obesity-associated-pancreatic-cancer.html

'Night owls' could have greater risk of type 2 diabetes and heart disease than those who are 'early birds'

Are you an early bird or a night owl? Our activity patterns and sleep cycles could influence our risk of diseases, such as type 2 diabetes and heart disease. New research published in Experimental Physiology has found that wake/sleep cycles cause metabolic differences and alter our body's preference for energy sources. The researchers found that those who stay up later have a reduced ability to use fat for energy, meaning fats may build up in the body and increase risk for type 2 diabetes and cardiovascular disease. source https://medicalxpress.com/news/2022-09-night-owls-greater-diabetes-heart.html

A healthy lifestyle almost halves the risk of dementia in people with type 2 diabetes

A healthy lifestyle reduces the risk of dementia in those with type 2 diabetes (T2D), according to a study of hundreds of thousands of people in the U.K. being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Stockholm, Sweden (19–23 Sept). source https://medicalxpress.com/news/2022-09-healthy-lifestyle-halves-dementia-people.html

China health chief tells public not to touch foreigners after first monkeypox case

A top Chinese health official has warned the public to avoid "skin-to-skin contact with foreigners" to prevent the spread of monkeypox after the country confirmed its first case. source https://medicalxpress.com/news/2022-09-china-health-chief-foreigners-monkeypox.html

A smartphone's camera and flash could help people measure blood oxygen levels at home

First, pause and take a deep breath. source https://medicalxpress.com/news/2022-09-smartphone-camera-people-blood-oxygen.html

China lifts weeks-long lockdown on southwest megacity Chengdu

Millions of people in the Chinese megacity of Chengdu emerged Monday from a COVID-19 lockdown that had closed schools, disrupted businesses and forced residents to stay home for over two weeks. source https://medicalxpress.com/news/2022-09-china-weeks-long-lockdown-southwest-megacity.html

The Twin You Didn’t Know You Had

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Artificial Intelligence may spell the end of the control group. source https://www.webmd.com/a-to-z-guides/features/ai-digital-twins?src=RSS_PUBLIC

Simple, inexpensive surgical procedure for diabetic foot ulcers greatly reduces healing time, amputation rates

Performing proactive surgery to adjust the mechanics of the foot, appears to be effective to treat diabetic foot ulcers, a common and debilitating complication of diabetes, without the potential complications and at significantly lower cost compared to conservative management. source https://medicalxpress.com/news/2022-09-simple-inexpensive-surgical-procedure-diabetic.html

Safer opioid supply program shows improved outcomes for people at high risk of overdose

For people at high risk of overdose enrolled in a safer opioid supply (SOS) program, there was a rapid decrease in emergency department visits and hospitalizations soon after initiation, according to new research published in Canadian Medical Association Journal (CMJA). These programs may help to address the devastating drug poisoning overdose crisis in Canada. source https://medicalxpress.com/news/2022-09-safer-opioid-outcomes-people-high.html

School start times and late screen time exacerbate sleep deprivation in US teenagers

With the school year underway around the U.S., parents and caregivers are once again faced with the age-old struggle of wrangling groggy kids out of bed in the morning. For parents of preteens and teenagers, it can be particularly challenging. source https://medicalxpress.com/news/2022-09-school-late-screen-exacerbate-deprivation.html

Excess weight, not high blood sugar, associated with increased risk of COVID-19 infection and long COVID

High body mass index (BMI), rather than high blood sugar levels, are associated with excess risks of COVID-19 infection and long COVID, according to a meta-analysis of over 30,000 UK adults from nine large prospective cohort studies. source https://medicalxpress.com/news/2022-09-excess-weight-high-blood-sugar.html

COVID-19 took serious toll on Native Hawaiian/Pacific Islander mental and physical health

Native Hawaiians/Pacific Islanders, or NH/PIs, comprising more than 20 ethnic groups hailing from Polynesia, Micronesia, and Melanesia, are understudied despite being the third fastest growing racial group in the United States. Two studies now report that NH/PIs have been deeply affected by the COVID-19 pandemic. source https://medicalxpress.com/news/2022-09-covid-toll-native-hawaiianpacific-islander.html

Cancer patients facing housing instability show greater risk of mortality

Health systems are increasingly interested in integrating health care with social care, but little is known about cancer patients' social welfare and how it affects their health outcomes. source https://medicalxpress.com/news/2022-09-cancer-patients-housing-instability-greater.html

Weight-Loss Surgery Has Long-Term Benefits for Pain, Mobility

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Though many patients regain some weight in the first couple of years after bariatric surgery, a new study finds pain and movement benefits seem to stand the test of time. source https://www.webmd.com/diet/obesity/news/20220916/weight-loss-surgery-has-long-term-benefits-for-pain-mobility?src=RSS_PUBLIC

New Science Reveals the Best Way to Take a Pill

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Standing? Sitting? Lying down? Your body position may impact how well oral medication works, Johns Hopkins scientists report. source https://www.webmd.com/drug-medication/news/20220916/new-science-reveals-the-best-way-to-take-a-pill?src=RSS_PUBLIC

Is it really healthy to restrict protein intake for kidney transplant recipients?

Conventional wisdom holds that low protein intake is essential for kidney disease patients. However, scientists from Osaka Metropolitan University demonstrated that it might not always be the case with their recent study on the relationship between protein intake and skeletal muscle mass in kidney transplant recipients. Their findings were published in Clinical Nutrition. source https://medicalxpress.com/news/2022-09-healthy-restrict-protein-intake-kidney.html

Researchers identify a gene therapy target for polycystic kidney disease

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported. The findings, published in Nature Communications, suggest a strategy for gene therapy with the potential to arrest or cure ADPKD. source https://medicalxpress.com/news/2022-09-gene-therapy-polycystic-kidney-disease.html

Could a pill help prevent a leading cause of childhood mortality?

Across much of the world, childhood diarrhea is a major killer. Could a probiotic pill somehow be engineered to help stop the scourge in its tracks? source https://medicalxpress.com/news/2022-09-pill-childhood-mortality.html

Adults show poorer cognition, better well-being with age

The young and old could learn a thing or two from each other, at least when it comes to mental health and cognition. source https://medicalxpress.com/news/2022-09-adults-poorer-cognition-well-being-age.html

Family Dinner: How to Make It Happen

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Families have changed and so have dinners. But many families still make it a priority to connect over a meal. Here’s how. source https://www.webmd.com/a-to-z-guides/features/family-dinners-are-important?src=RSS_PUBLIC

Combined birth control pill linked with increased risk of blood clots in obese women

Obese women who use oral contraceptives containing estrogen and progestin have a 24-fold increased risk of venous thromboembolism (VTE) compared with non-obese women not using the drugs, according to a review paper published today in ESC Heart Failure. source https://medicalxpress.com/news/2022-09-combined-birth-pill-linked-blood.html

Experimental test promises to predict side-effects and cancer's return in patients treated with immunotherapy

A single research test has the potential to predict which patients treated with immunotherapies—which harness the immune system to attack cancer cells—are likely to have their cancer recur or have severe side effects, a new study found. source https://medicalxpress.com/news/2022-09-experimental-side-effects-cancer-patients-immunotherapy.html

Research suggests commonly used prostate cancer treatment rewires engine of prostate tumors

Drugs like enzalutamide that inhibit male hormones from activating the androgen receptor have been used to treat advanced prostate cancer for more than a decade. While successful in most cases, these drugs can eventually stop working, but there is a limited understanding about how this change occurs. source https://medicalxpress.com/news/2022-09-commonly-prostate-cancer-treatment-rewires.html

Bangladeshi mystic fights demons with psychiatry

Evil spirits bedevil the families that seek blessings from an elderly Bangladeshi mystic—but he knows his prayers alone are not enough to soothe their troubled minds. source https://medicalxpress.com/news/2022-09-bangladeshi-mystic-demons-psychiatry.html

Study suggests portable thermal imaging could help assess hand hygiene technique among health care professionals

Findings from a pilot study published today in the American Journal of Infection Control (AJIC) suggest that portable thermal imaging cameras might provide a new approach to assessing and improving hand-hygiene practices among health care professionals (HCPs). source https://medicalxpress.com/news/2022-09-portable-thermal-imaging-hygiene-technique.html

Study finds higher complication rate after heart attack in people with autoimmune disease

After a heart attack, people with an autoimmune disease were more likely to die, develop heart failure or have a second heart attack compared to people without an autoimmune disease, according to new research published today in the Journal of the American Heart Association. source https://medicalxpress.com/news/2022-09-higher-complication-heart-people-autoimmune.html

Air pollution may spur irregular heart rhythms in healthy teens

Breathing particulate matter (i.e., tiny particles suspended in the air) air pollution may trigger irregular heart rhythms (arrhythmias) in healthy teenagers, according to new research published today in the Journal of the American Heart Association. source https://medicalxpress.com/news/2022-09-air-pollution-spur-irregular-heart.html

Survey finds stress and worry over the state of the world keeps some Americans up at night

A new national survey by The Ohio State University Wexner Medical Center finds many Americans are losing sleep over stress and worry about the current state of the world. After a global pandemic, polarizing political division and more than two years of turbulent events, nearly one in five survey respondents report struggling to fall asleep at night. source https://medicalxpress.com/news/2022-09-survey-stress-state-world-americans.html

Past history of abuse leads to worse menopause symptoms

Adversity occurring early in a woman's life will likely continue taking its toll physically and mentally years after those stressors have been removed. A new study suggests that a history of psychosocial stressors (physical or sexual abuse or financial instability) can lead to worse menopause symptoms and poorer well-being almost 2 decades later. Study results are published online today in Menopause. source https://medicalxpress.com/news/2022-09-history-abuse-worse-menopause-symptoms.html

TikTok 'Slugging' Trend Has People Coating Their Faces With Grease

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Slugging involves slathering some sort of sealing agent -- like Vaseline or another petroleum-based ointment -- onto the skin. source https://www.webmd.com/beauty/news/20220913/tiktok-slugging-trend-has-people-coating-their-faces-with-grease?src=RSS_PUBLIC

Technique developed in mice could aid detection of cancer in dense breasts

A two-pronged approach to imaging breast density in mice, developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, has resulted in better detection of changes in breast tissue, including spotting early signs of cancer. The researchers hope that this approach will be translated from mice and improve breast imaging for people; it may also help with prognosis of disease as density can be linked to specific patterns of mammary gland growth, including signs of cancer development. source https://medicalxpress.com/news/2022-09-technique-mice-aid-cancer-dense.html

Foster family placement leads to sustained cognitive gains after severe early deprivation

Millions of children worldwide are under legal guardianship of the state, often due to abuse, neglect, parental death or other circumstances—leaving governments to determine how best to care for them. The Bucharest Early Intervention Project has shed light on ways to improve the quality of caregiving for children. Initiated in 2000, the BEIP is a randomized controlled trial of foster care as an alternative to institutional care for children who experienced severe psychosocial deprivation. source https://medicalxpress.com/news/2022-09-foster-family-placement-sustained-cognitive.html

Study finds white children more likely to be overdiagnosed for ADHD

A new study led by Paul Morgan, Harry and Marion Eberly Faculty Fellow and professor of education (educational theory and policy) and demography, and published in the Journal of Learning Disabilities, examines which sociodemographic groups of children are more likely to be overdiagnosed and overtreated for ADHD. source https://medicalxpress.com/news/2022-09-white-children-overdiagnosed-adhd.html

Why focusing COVID vaccination efforts on least advantaged populations benefits everyone

When vaccine access is prioritized for the most disadvantaged communities, it improves both social utility and equity—even when such populations have strong vaccine hesitancy. source https://medicalxpress.com/news/2022-09-focusing-covid-vaccination-efforts-advantaged.html

Patients prefer stool test to colonoscopy

Three-quarters of people prefer to do a fecal immunochemical test (FIT) rather than a colonoscopy for their regular colorectal cancer screening, according to a new Cedars-Sinai study. source https://medicalxpress.com/news/2022-09-patients-stool-colonoscopy.html

What do aged care residents do all day? We tracked their time use to find out

What's the daily routine like for older people in residential aged care facilities? source https://medicalxpress.com/news/2022-09-aged-residents-day-tracked.html

Study of cancer immunotherapy patients reveals markers of treatment response

The treatment of blood cancers has dramatically improved in the last five years, thanks to a new class of cancer immunotherapies called CAR-T cell therapy. This therapy—which involves engineering a patient's own T cells in the lab to kill cancer cells and then infusing them back into the patient—cures about 40% of people with otherwise incurable lymphoma. But others relapse or don't respond to the treatment at all. source https://medicalxpress.com/news/2022-09-cancer-immunotherapy-patients-reveals-markers.html

RET inhibitor selpercatinib demonstrates durable responses in tumor-agnostic population

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center. source https://medicalxpress.com/news/2022-09-ret-inhibitor-selpercatinib-durable-responses.html

Twice-daily nasal irrigation reduces COVID-related illness, death

Starting twice daily flushing of the mucus-lined nasal cavity with a mild saline solution soon after testing positive for COVID-19 can significantly reduce hospitalization and death, investigators report. source https://medicalxpress.com/news/2022-09-twice-daily-nasal-irrigation-covid-related-illness.html

Exploring how many drinks is too many

A new rodent study shows that even small quantities of alcohol can trigger epigenomic and transcriptomic changes in brain circuitry in an area that is crucial in the development of addiction. source https://medicalxpress.com/news/2022-09-exploring.html

A Woman of Wonder Commits to Cancer Research

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Former Wonder Woman Star Lynda Carter is creating the Robert & Lynda Carter Altman Family Foundation Research Fund in honor of her late husband who died of a rare form of blood cancer. source https://www.webmd.com/cancer/news/20220909/a-woman-of-wonder-commits-to-cancer-research?src=RSS_PUBLIC

Blood marker which predicts the risk of osteoporotic hip fractures in older men

NUS scientists have discovered that blood levels of the chemokine protein CXCL9 reliably predict the risk of osteoporotic hip fractures in Chinese men. source https://medicalxpress.com/news/2022-09-blood-marker-osteoporotic-hip-fractures.html

Americans give health care system failing mark: AP-NORC poll

When Emmanuel Obeng-Dankwa is worried about making rent on his New York City apartment, he sometimes holds off on filling his blood pressure medication. source https://medicalxpress.com/news/2022-09-americans-health-ap-norc-poll.html

Grandma and Grandpa on Drugs: The Senior Citizen Opioid Epidemic

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The number of opioid-related deaths of Americans ages 55 and up soared 1,886% between 1999 and 2019 source https://www.webmd.com/healthy-aging/features/grandma-grandpa-drugs-senior-citizen-opioid-epidemic?src=RSS_PUBLIC

China quarantines college students under strict COVID policy

Almost 500 students at China's premier college for broadcast journalists have been sent to a quarantine center after a handful of COVID-19 cases were detected in their dormitory. source https://medicalxpress.com/news/2022-09-china-quarantines-college-students-strict.html

Malaria booster vaccine continues to meet WHO-specified 75% efficacy goal

Researchers from the University of Oxford and their partners have today reported new findings from their Phase 2b trial following the administration of a booster dose of the candidate malaria vaccine, R21/Matrix-M—which previously demonstrated high-level efficacy of 77% over the following 12 months in young west African children in 2021. source https://medicalxpress.com/news/2022-09-malaria-booster-vaccine-who-specified-efficacy.html

Scientists discover how air pollution triggers lung cancer

Scientists said Saturday they had identified the mechanism through which air pollution triggers lung cancer in non-smokers, a discovery one expert hailed as "an important step for science—and for society". source https://medicalxpress.com/news/2022-09-scientists-air-pollution-triggers-lung.html

Sweeteners may be linked to heart disease risk, study suggests

A large study suggested Thursday that artificial sweetener could be associated with a higher risk of heart disease, however experts urged caution about the findings. source https://medicalxpress.com/news/2022-09-sweeteners-linked-heart-disease.html

Immune cells engineered to battle cancer can be turned 'on' or 'off'

The billions of immune cells that help protect us from diseases do amazing things, but sometimes they need a little boost. For decades, scientists have been trying to figure out ways to engineer living immune cells to better combat aggressive diseases, like cancer. source https://medicalxpress.com/news/2022-09-immune-cells-cancer.html

Doomscrolling is literally bad for your health. Here are four tips to help you stop

Doomscrolling can be a normal reaction to living through uncertain times. It's natural to want to understand dramatic events unfolding around you and to seek out information when you're afraid. But becoming absorbed in bad news for too long can be detrimental. source https://medicalxpress.com/news/2022-09-doomscrolling-literally-bad-health.html

Kids Walking, Biking to School Can Lead to Long-Term Fitness

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Recent research suggests kids who walk, skateboard or ride their bikes to school when they are young are more likely to keep it up as they get older, reaping the health benefits. source https://www.webmd.com/parenting/news/20220909/getting-kids-walking-biking-to-school-can-lead-to-long-term-fitness?src=RSS_PUBLIC

Breaking down proteins: How starving cancer cells switch food sources

Cancer cells often grow in environments that are low in nutrients, and they cope with this challenge by switching their metabolism to using proteins as alternative "food". Building on genetic screens, an international team of scientists could identify the protein LYSET as part of a pathway that allows cancer cells to make this switch. Their findings are now published in the journal Science. source https://medicalxpress.com/news/2022-09-proteins-starving-cancer-cells-food.html

Vaccine expected to induce strong immune responses against 2022 monkeypox virus, research shows

New research has suggested that recommended vaccinia virus (VACV)-based vaccines will mount a robust immune response against the monkeypox virus observed in the current outbreak (MPXV-2022). source https://medicalxpress.com/news/2022-09-vaccine-strong-immune-responses-monkeypox.html

New technology to visualize axonal fiber bundles on the retina for early diagnosis of optic neuropathies

A research team led by the Department of Ophthalmology, School of Clinical Medicine, LKS Faculty of Medicine of The University of Hong Kong (HKUMed), with collaborators from the Faculty of Medicine of The Chinese University of Hong Kong (CU Medicine) and local and international partners, have developed a new technology ROTA (Retinal nerve fiber layer Optical Texture Analysis) to unveil the optical texture and trajectories of the axonal fiber bundles on the retina. ROTA outperforms the current clinical standards, attaining 15.0% to 28.4% higher in sensitivity in detecting early optic nerve damage in glaucoma—the leading cause of irreversible blindness. The research has been published in Nature Biomedical Engineering. source https://medicalxpress.com/news/2022-09-technology-visualize-axonal-fiber-bundles.html

Platinum-based chemotherapy distribution within a tumor may predict ovarian cancer treatment resistance

A team of researchers from Japan has discovered that the distribution of platinum within a tumor following platinum-based chemotherapy treatment of ovarian cancer may predict whether the tumor will be resistant to further treatment. The research could offer ways to manage treatment for women whose tumors may be resistant to further platinum-based chemotherapy. source https://medicalxpress.com/news/2022-09-platinum-based-chemotherapy-tumor-ovarian-cancer.html

Study examines how to improve hospitalized patients' access to antimicrobials

Published in the Journal of the American Pharmacist's Association, University of Minnesota researchers found that establishing better mechanisms for information sharing and collaboration between healthcare institutions may help facilitate timely and effective acquisition of non-stocked antimicrobials. source https://medicalxpress.com/news/2022-09-hospitalized-patients-access-antimicrobials.html

Individuals with type 2 diabetes respond differently to exercise

Regular exercise helps prevent and delay the development of type 2 diabetes and its complications. Researchers at Karolinska Institutet, together with a team of international scientists, have discovered that activation of the immune system in skeletal muscle during exercise may underlie the difference in how individuals with type 2 diabetes perceive and respond to exercise. These findings are published in the journal Science Advances. source https://medicalxpress.com/news/2022-09-individuals-diabetes-differently.html

Study finds damage in the lungs of chronic e-cigarette users

Chronic use of e-cigarettes, commonly known as vaping, can result in progressive small airway obstruction and asthma-like symptoms such as shortness of breath and chest pains, according to researchers at Massachusetts General Hospital (MGH). In the first study to microscopically evaluate the pulmonary tissue of e-cigarette users for chronic disease, the team found in a small sample of patients fibrosis and damage in the small airways, similar to the chemical inhalation damage to the lungs typically seen in soldiers returning from overseas conflicts who had inhaled mustard or similar types of noxious gases. The study was published in New England Journal of Medicine Evidence. source https://medicalxpress.com/news/2022-09-lungs-chronic-e-cigarette-users.html

Hong Kong extends digital vaccine pass to kids as young as five

Hong Kong will extend a digital vaccination pass that controls which premises residents can enter to children as young as five years old, authorities announced Thursday. source https://medicalxpress.com/news/2022-09-hong-kong-digital-vaccine-kids.html

FDA panel backs much-debated ALS drug in rare, 2nd review

A panel of federal health advisers voted Wednesday to recommend approval for an experimental drug to treat Lou Gehrig's disease, a remarkable turnaround for the much-debated medication that was previously rejected by the same group earlier this year. source https://medicalxpress.com/news/2022-09-fda-panel-much-debated-als-drug.html

How to deal with sleep problems during heat waves

With heatwaves occurring more frequently, investigators from the European Insomnia Network recently explored how outdoor nighttime temperature changes affect body temperature and sleep quality. Their review of the literature, which is published in the Journal of Sleep Research, indicates that environmental temperatures outside the thermal comfort can strongly affect human sleep by disturbing the body's ability to thermoregulate. source https://medicalxpress.com/news/2022-09-problems.html

Have you heard soy is linked to cancer risk or can 'feminize' men? Here's what the science really says

Soy is common in many Asian cuisines, and is growing more popular in Western countries as many people aim for predominantly plant-based diets. It offers many potential health benefits and is generally cheaper than meat. source https://medicalxpress.com/news/2022-09-heard-soy-linked-cancer-feminize.html

Investigating racial differences in multiple myeloma

Investigators have identified distinct epigenetic pathways in African American and European American patients diagnosed with multiple myeloma, according to a Northwestern Medicine study published in the Journal of Hematology & Oncology. source https://medicalxpress.com/news/2022-09-racial-differences-multiple-myeloma.html

Researchers develop bioresorbable, implantable device to block pain signals from peripheral nerves

Due to their high efficacy, opioids are used widely for the management of neuropathic pain, despite the increasing rates of opioid addiction and deaths due to overdose. To avoid these side effects, there is an urgent need for pain management approaches that can substitute opioid use. source https://medicalxpress.com/news/2022-09-bioresorbable-implantable-device-block-pain.html

What Will the Inflation Reduction Act Do for Your Healthcare?

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For many Americans, the IRA could meaningfully improve their ability to afford the care they need. Here's a breakdown of what the bill does for Medicare beneficiaries, adults who purchase private insurance coverage, and Medicaid enrollees. source https://www.webmd.com/health-insurance/features/ira-bill-healthcare?src=RSS_PUBLIC

Vitamin D deficiency in melanoma patients associated with worse overall survival, new study finds

Vitamin D levels affect overall survival for melanoma (skin cancer) patients, a new study presented at the 31st European Academy of Dermatology and Venereology (EADV) Congress has shown. source https://medicalxpress.com/news/2022-09-vitamin-d-deficiency-melanoma-patients.html

Children with autism benefit when parents are trained to provide at-home interventions

Training and empowering parents to provide at-home interventions to children with autism spectrum disorder helps children improve in positive behaviors and language communication skills says a new study from BYU. source https://medicalxpress.com/news/2022-09-children-autism-benefit-parents-at-home.html

Cold physical plasma kills coronaviruses

A Greifswald research team from the Center of Excellence ZIK plasmatis at the Leibniz Institute for Plasma Science and Technology e.V. (INP) was able to demonstrate for the first time in laboratory experiments the inactivation of coronaviruses by physical plasma. The new method promises innovative therapies for the current pandemic and other infectious diseases. source https://medicalxpress.com/news/2022-09-cold-physical-plasma-coronaviruses.html

How does nature nurture the brain?

After a 60-minute walk in nature, activity in brain regions involved in stress processing decreases. This is the finding of a recent study by the Lise Meitner Group for Environmental Neuroscience at the Max Planck Institute for Human Development, published in Molecular Psychiatry. source https://medicalxpress.com/news/2022-09-nature-nurture-brain.html

Scientists diagnose Alzheimer's disease by blood test

Alzheimer's disease (AD) is characterized by a decline in cognitive function, memory loss, and in severe cases, language impairment, and ultimately the loss of independent living ability. According to estimates by Chinese Center for disease Control and Prevention, there are about 10 million AD patients in China, which will exceed 30 million by 2050, making it the country with the largest number of AD patients in the world. However, at present, Chinese residents have low awareness and attention to AD, and there are generally low diagnosis rates (especially early diagnosis) and low treatment rates. source https://medicalxpress.com/news/2022-09-scientists-alzheimer-disease-blood.html

China's Chengdu enforces strict lockdown despite earthquake

Authorities in southwestern China's Chengdu have maintained strict COVID-19 lockdown measures on the city of 21 million despite a major earthquake that killed at least 65 people in outlying areas. source https://medicalxpress.com/news/2022-09-china-chengdu-strict-lockdown-earthquake.html

Hong Kong records first monkeypox case

Hong Kong recorded its first case of monkeypox in a 30-year-old man who had travelled into the city and showed symptoms during hotel quarantine, health officials said Tuesday. source https://medicalxpress.com/news/2022-09-hong-kong-monkeypox-case.html

High blood pressure awareness, control improved with better access to primary health care

Having easier access to primary care physicians may increase high blood pressure awareness and control regardless of where a person lives, according to new research published today in Circulation: Cardiovascular Quality and Outcomes. source https://medicalxpress.com/news/2022-09-high-blood-pressure-awareness-access.html

WIC participation associated with improved birth outcomes, lower infant mortality

A systematic review of the most recently available evidence has found that participation in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is likely associated with improved birth outcomes and lower infant mortality. In addition, participation in WIC may increase receipt of child preventative services, such as vaccines. The review is published in Annals of Internal Medicine. source https://medicalxpress.com/news/2022-09-wic-birth-outcomes-infant-mortality.html

Teenagers more likely to vape if their parents smoke

Teenagers whose parents are smokers are 55% more likely to try e-cigarettes, according to research presented at the European Respiratory Society International Congress in Barcelona, Spain. In a large study of Irish teenagers, the researchers have also found that the proportion who have tried e-cigarettes has been increasing dramatically and that although boys are more likely to use e-cigarettes, the rate of use among girls in increasing more rapidly. source https://medicalxpress.com/news/2022-09-teenagers-vape-parents.html

Difficult birth stories can give people an appreciation for life

In the first study of its kind, researchers investigated the impact of stories around conception and birth and how they affect the individuals involved and their familial relationships. Previous research in this area has focused on the impact on the experience of difficult births and conceptions but not on how they were communicated to the child/adult. source https://medicalxpress.com/news/2022-09-difficult-birth-stories-people-life.html

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

Constitutively activated G proteins caused by specific mutations mediate the development of multiple malignancies. The mutated Gαq/11 are perceived as oncogenic drivers in the vast majority of uveal melanoma (UM) cases, making directly targeting Gαq/11 to be a promising strategy for combating UM. source https://medicalxpress.com/news/2022-09-discovery-small-molecule-gq11-protein.html

Can 'random noise' unlock our learning potential?

Though many of us may seek a quiet place in which to study, "noise" may play a key role in helping some people improve their learning potential. source https://medicalxpress.com/news/2022-09-random-noise-potential.html

Researchers investigate potential treatment for Chagas disease

University of Oklahoma and Baylor College of Medicine researchers are investigating a potential treatment for a disease that affects as many as 8 million people in the United States and Latin America. source https://medicalxpress.com/news/2022-09-potential-treatment-chagas-disease.html

How changes in length of day change the brain and subsequent behavior

Seasonal changes in light—longer days in summer, shorter in winter—have long been associated with human behaviors, affecting everything from sleep and eating patterns to brain and hormonal activity. Seasonal affective disorder (SAD) is a prime example: A type of depression related to diminished exposure to natural sunlight, typically occurring during winter months and more often at higher latitudes when daylight hours are shortest. source https://medicalxpress.com/news/2022-09-length-day-brain-subsequent-behavior.html

China locks down 65 million as holiday travel peak looms

China has locked down 65 million of its citizens under tough COVID-19 restrictions and is discouraging domestic travel during upcoming national holidays. source https://medicalxpress.com/news/2022-09-china-million-holiday-peak-looms.html

Bronchodilators don't improve smoking-related respiratory symptoms in people without COPD

Researchers supported by the National Institutes of Health have found that dual bronchodilators—long-lasting inhalers that relax the airways and make it easier to breathe—do little to help people who do not have chronic obstructive pulmonary disease (COPD), but who do have respiratory symptoms and a history of smoking. source https://medicalxpress.com/news/2022-09-bronchodilators-dont-smoking-related-respiratory-symptoms.html

Treatment improves cognition in Down Syndrome patients

A new hormone treatment improved the cognitive function of six men with Down Syndrome by 10-30 percent, scientists said Thursday, adding the "promising" results may raise hopes of improving patients' quality of life. source https://medicalxpress.com/news/2022-09-treatment-cognition-syndrome-patients.html

UK approves Pfizer bivalent COVID vaccine ahead of booster drive

The UK's drug regulator said Saturday it had approved an updated COVID-19 jab by Pfizer/BioNTEch targeting the original virus and a subvariant ahead of an autumn booster drive. source https://medicalxpress.com/news/2022-09-uk-pfizer-bivalent-covid-vaccine.html

UK to begin rollout of new COVID-19 vaccination campaign

The U.K. will begin its autumn COVID-19 vaccination campaign in the coming weeks after authorizing booster shots made by Pfizer and Moderna that have been modified to target both the original virus and the widely circulating omicron variant. source https://medicalxpress.com/news/2022-09-uk-rollout-covid-vaccination-campaign.html

New York polio case stirs fear, vaccine push

When Brittany Strickland heard that the United States recorded its first polio case in almost a decade, she was "deathly scared"—the 33-year-old wasn't vaccinated against the disabling disease. source https://medicalxpress.com/news/2022-09-york-polio-case-vaccine.html

UT Southwestern geriatric fracture initiatives result in expedited care and shorter hospital stays

A multidisciplinary effort to improve care for older patients who arrive at the emergency room with a hip fracture has decreased the time before they have surgery, shortened hospital stays, and resulted in better follow-up care, UT Southwestern physicians reported in Geriatric Nursing. source https://medicalxpress.com/news/2022-09-ut-southwestern-geriatric-fracture-result.html

Think You Have Long COVID? See Your Primary Care Doc First

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Many patients dealing long COVID symptoms might be tempted to go straight to a specialist. But medical experts recommend starting in a different place: primary care. source https://www.webmd.com/lung/news/20220902/think-you-have-long-covid-see-your-primary-care-doc-first?src=RSS_PUBLIC

Yes, you can reheat food more than once

Preparing meals in bulk and reheating is a great way to save time in the kitchen and can also help to reduce food waste. You might have heard the myth that you can only reheat food once before it becomes unsafe to eat. source https://medicalxpress.com/news/2022-09-reheat-food.html

The Truth About Soy and Breast Cancer

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WebMD clears up the confusion on how this plant protein affects your breast cancer risk. source https://www.webmd.com/breast-cancer/features/soy-effects-on-breast-cancer?src=RSS_PUBLIC

Axolotls can regenerate their brains, revealing secrets of brain evolution and regeneration

The axolotl (Ambystoma mexicanum) is an aquatic salamander renowned for its ability to regenerate its spinal cord, heart and limbs. These amphibians also readily make new neurons throughout their lives. In 1964, researchers observed that adult axolotls could regenerate parts of their brains, even if a large section was completely removed. But one study found that axolotl brain regeneration has a limited ability to rebuild original tissue structure. source https://medicalxpress.com/news/2022-09-axolotls-regenerate-brains-revealing-secrets.html

Recent findings suggest new omicron BA.2.75 is as susceptible to antibodies as the currently dominant variant

In a recent study, researchers from Karolinska Institutet and others have characterized the new omicron variant BA.2.75, comparing its ability to evade antibodies against current and previous variants. The study, published in the journal The Lancet Infectious Diseases, suggests that BA.2.75 is not more resistant to antibodies than the currently dominating BA.5, which is positive news. source https://medicalxpress.com/news/2022-09-omicron-ba275-susceptible-antibodies-dominant.html

Circadian rhythm disruption found to be common among mental health disorders

Anxiety, autism, schizophrenia and Tourette syndrome each have their own distinguishing characteristics, but one factor bridging these and most other mental disorders is circadian rhythm disruption, according to a team of neuroscience, pharmaceutical sciences and computer science researchers at the University of California, Irvine. source https://medicalxpress.com/news/2022-09-circadian-rhythm-disruption-common-mental.html

Deep in the bile ducts, researchers explore how cancer arises

A Wilmot Cancer Institute scientist discovered how gene mutations fuel the growth of bile duct cancer, a rare but aggressive type of liver cancer that has been on the rise in the U.S. source https://medicalxpress.com/news/2022-09-deep-bile-ducts-explore-cancer.html

Finland's first vaccine mandate against smallpox improved long-term vaccine uptake

Researchers from University of Turku investigated how the vaccine mandate against the deadly childhood infection smallpox was successful at increasing vaccination coverage in 19th-century Finland. source https://medicalxpress.com/news/2022-09-finland-vaccine-mandate-smallpox-long-term.html

Why Canada's low-risk alcohol use guidelines have been slashed to six drinks per week

New Canadian guidelines for reducing risks to health from alcohol use were released for public comment this week. Key messages include: source https://medicalxpress.com/news/2022-09-canada-low-risk-alcohol-guidelines-slashed.html

International effort in Ukraine provides a blueprint for responding to global health crises

When Russian forces invaded Ukraine in February 2022, disruptions in civilian life (particularly to the health care system) created a dire situation for Ukrainian children with cancer and blood disorders. In response, the St. Jude Global initiative of St. Jude Children's Research Hospital banded together with many international partners and formed Supporting Action for Emergency Response in Ukraine (SAFER Ukraine). An account of SAFER Ukraine appears today in The Lancet Haematology. source https://medicalxpress.com/news/2022-09-international-effort-ukraine-blueprint-global.html

Belgium records first monkeypox death

Belgium has recorded its first death of a patient suffering from monkeypox, the third in Europe, according to the weekly report on the outbreak from the Sciensano public health institute. source https://medicalxpress.com/news/2022-09-belgium-monkeypox-death.html

Research team reveals mechanisms at work in progression of pancreatic cysts to pancreatic cancer

Pancreatic cysts have gained substantial attention in recent years because they represent one of the only precursors of pancreatic cancer identifiable through radiologic imaging. Although most of these cysts, also known as pancreatic intraductal papillary mucinous neoplasms (IPMNs), will remain benign, a subset of these neoplasms will progress to invasive cancer. While the immune system has been thought to play a role in the progression of IPMNs into pancreatic cancer, the specific mechanisms of its role has been unclear. source https://medicalxpress.com/news/2022-09-team-reveals-mechanisms-pancreatic-cysts.html

Over-The-Counter Hearing Aids: Good News, With Some Complications

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Audiologists, even those who generally support the idea of non-prescription hearing aids, worry that without an initial evaluation and ongoing care, people will buy the devices without understanding how to use or adjust them. source https://www.webmd.com/a-to-z-guides/features/fda-otc-hearing-aids?src=RSS_PUBLIC