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Showing posts from August, 2022

Study reveals link between disrupted enzyme and intellectual disability

A new study, published in Frontiers in Molecular Neuroscience, reveals how a rare genetic mutation leads to intellectual disability. The P212L mutation in an enzyme called CaMKIIalpha, which is important for learning and memory, is known to be linked to intellectual disability. However, the exact process by which the mutation affected the enzyme's activity was unclear, until now. A newly developed method of protein analysis has shown that the P212L mutation causes dramatically more activation of CaMKIIalpha. This has enabled researchers to identify a potential treatment using existing medicine, and this new method could be adapted to analyze other genetic causes of disability and disease in the future. source https://medicalxpress.com/news/2022-08-reveals-link-disrupted-enzyme-intellectual.html

3D imaging helps to better understand the early stages of Alzheimer's disease

Using a novel 3D imaging technology, researchers at Karolinska Institutet, among others, have been able to comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease. The results, published in the journal Acta Neuropathologica, may make it possible in the future to have a more precise neuropathological diagnosis of the Alzheimer's disease spectrum at a very early stage. source https://medicalxpress.com/news/2022-08-3d-imaging-early-stages-alzheimer.html

Leukemia drug shows potential against metastatic HER2-positive breast cancer

In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain. source https://medicalxpress.com/news/2022-08-leukemia-drug-potential-metastatic-her2-positive.html

Gut and lung organoids open the door to innate immune cell therapies

King's researchers have found an innovative approach for expanding and maturing innate immune cells in a dish. source https://medicalxpress.com/news/2022-08-gut-lung-organoids-door-innate.html

Enhancing the effect of protein-based COVID-19 vaccines

Ironically, some vaccines need their own "boosters." Adding an ingredient called an adjuvant can help vaccines elicit a more robust immune response, better training the body to fight a pathogen. In a new study in ACS Infectious Diseases, researchers report a substance that boosted the immune response to an experimental COVID-19 shot in mice by 25 times, compared to injection with the vaccine alone. source https://medicalxpress.com/news/2022-08-effect-protein-based-covid-vaccines.html

Low physical function after age 65 associated with future cardiovascular disease

Among people older than age 65 who were assessed using a short physical function test, having lower physical function was independently associated with a greater risk of developing heart attack, heart failure and stroke, according to new research published today in the Journal of the American Heart Association. source https://medicalxpress.com/news/2022-08-physical-function-age-future-cardiovascular.html

Addiction management is key to treating heart infection in people who inject drugs

Managing a potentially deadly heart infection is complex in people who inject drugs, including opioids, stimulants, and others, and requires a unique approach to care including consultation with an addiction specialist, according to a new American Heart Association Scientific Statement published today in the Association's flagship journal Circulation. source https://medicalxpress.com/news/2022-08-addiction-key-heart-infection-people.html

New blood test for ALS promises rapid diagnosis

Patients with ALS, one of the most serious neurological diseases known, have been hampered by the time it takes to receive an accurate diagnosis. The period between the onset of symptoms and diagnosis averages over a year, precious time for a disease in which most patients die between 2-5 years from diagnosis. Researchers estimate that an inaccurate diagnosis occurs in 13-68% of cases. source https://medicalxpress.com/news/2022-08-blood-als-rapid-diagnosis.html

Genetic discovery could improve treatment of colorectal cancer

EPFL scientists have discovered a rare gene in the tumors of some colorectal cancer patients. This finding could lead to more accurate diagnoses and, eventually, personalized treatments that target the protein expressed by the gene. source https://medicalxpress.com/news/2022-08-genetic-discovery-treatment-colorectal-cancer.html

Peanuts present a nutty solution for weight loss

A handful of peanuts might be a favorite snack, but according to new research from the University of South Australia it's also a way to help shed some unwanted kilos and keep your cardio health in check. source https://medicalxpress.com/news/2022-08-peanuts-nutty-solution-weight-loss.html

Physician 'gun lover' offers suggestions for safer Second Amendment

Michael Rose, MD, MPH, is a proud gun owner, hunter, and native North Dakotan who practices medicine in the heart of Baltimore. Dr. Rose understands how his personal and professional lives may seem at odds with one another. But in a new personal essay published in Annals of Internal Medicine, Dr. Rose draws upon an insider's perspective to offer suggestions for more common-sense gun laws and a safer Second Amendment. source https://medicalxpress.com/news/2022-08-physician-gun-lover-safer-amendment.html

China imposes COVID-19 lockdowns for millions around Beijing

Millions of people in areas surrounding China's capital were ordered into lockdown Tuesday, with authorities doubling down on efforts to contain COVID-19 ahead of a key ruling Communist Party meeting this year. source https://medicalxpress.com/news/2022-08-china-imposes-covid-lockdowns-millions.html

State-level earned income tax credit linked to reduction in high-risk HIV behavior among single mothers

UCLA research finds that a refundable State-level Earned Income Tax Credit (SEITC) of 10% or above the Federal EITC was associated with a 21% relative risk reduction in reported behavior that could put single mothers at high risk for becoming infected with HIV during the previous year. Also, a 10 percentage-point increase in SEITC was linked to a 38% relative reduction in the same reported high-risk behavior the previous year. source https://medicalxpress.com/news/2022-08-state-level-income-tax-credit-linked.html

Pregnant women exposed to cancer-causing chemicals in dishware, hair coloring, plastics, and pesticides: study

Pregnant women in the U.S. are being exposed to chemicals like melamine, cyanuric acid, and aromatic amines that can increase the risk of cancer and harm child development, according to researchers at UC San Francisco and Johns Hopkins Bloomberg School of Public Health. source https://medicalxpress.com/news/2022-08-pregnant-women-exposed-cancer-causing-chemicals.html

Allopurinol does not improve cardiovascular outcomes in ischemic heart disease patients

The gout medicine allopurinol has failed to reduce the primary endpoint of nonfatal myocardial infarction, nonfatal stroke or cardiovascular death in patients with ischemic heart disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2022. source https://medicalxpress.com/news/2022-08-allopurinol-cardiovascular-outcomes-ischemic-heart.html

Protein 'traffic jam' in neurons linked to neurodegeneration

Neurodegenerative disorders such as Alzheimer's and Parkinson's disease are associated with atypical proteins that form tangles in the brain, killing neurons. Neurobiologists at EPFL have now identified some key mechanisms underlying the formation of these tangles. source https://medicalxpress.com/news/2022-08-protein-traffic-neurons-linked-neurodegeneration.html

Republicans and Blacks most hesitant to get COVID vaccine, spatial analysis finds

Vaccine hesitancy remains a public health challenge that cuts across the country as the COVID-19 pandemic drags on, but Republican voters and Black people are among the most hesitant to get the shot, according to a new Portland State University study. source https://medicalxpress.com/news/2022-08-republicans-blacks-hesitant-covid-vaccine.html

Boosting duration, intensity and frequency of physical activity may lower heart failure risk

A six-year analysis of more than 94,000 adults in the U.K. Biobank with no history of heart failure at enrollment has found that engaging in moderate or vigorous physical activity may lower the risk of developing heart failure, according to new research published today in the American Heart Association's journal Circulation. source https://medicalxpress.com/news/2022-08-boosting-duration-intensity-frequency-physical.html

41% of teenagers can't tell the difference between true and fake online health messages

A new study has found that teenagers have a hard time discerning between fake and true health messages. Only 48% of the participants trusted accurate health messages (without editorial elements) more than fake ones. Meanwhile, 41% considered fake and true neutral messages equally trustworthy and 11% considered true neutral health messages less trustworthy than fake health messages. The results highlight a need for better training of teenagers to navigate a world where fake health news is so widespread. source https://medicalxpress.com/news/2022-08-teenagers-difference-true-fake-online.html

Access to paid sick leave linked to lower mortality rate among US adult workers

Access to paid sick leave is linked to a lower rate of mortality among US working age men and women, according to new research in the American Journal of Preventive Medicine. The study shows that laws requiring employers to provide paid sick leave are effective in reducing mortality from suicide and homicide among men and homicide and alcohol-related causes among women. The findings also demonstrate that state laws that preempt local governments from enacting such mandates likely contributed to recent increases in mortality among working adults (up 6% from 2010-2017). source https://medicalxpress.com/news/2022-08-access-paid-sick-linked-mortality.html

'Magic mushroom' psychedelic may help heavy drinkers quit

The compound in psychedelic mushrooms helped heavy drinkers cut back or quit entirely in the most rigorous test of psilocybin for alcoholism. source https://medicalxpress.com/news/2022-08-magic-mushroom-psychedelic-heavy-drinkers.html

Population-based study: Autoimmune disorders increase risk of cardiovascular disease

About 10% of the population in high income regions like Europe and the United States has been diagnosed with one or multiple autoimmune disorders. Examples are rheumatoid arthritis, psoriasis, systemic sclerosis, lupus erythematosus and type I diabetes. Although earlier research has suggested associations between some of these disorders and a higher risk of cardiovascular disease, these studies were often too small and limited to selected autoimmune or selected cardiovascular conditions to draw conclusive evidence on the necessity of cardiovascular disease prevention among patients with autoimmune disease, until now. source https://medicalxpress.com/news/2022-08-population-based-autoimmune-disorders-cardiovascular-disease.html

Pediatric cardiologists uncover possible cause of racial disparity affecting congenital heart disease

Race was already known to matter when it came to health outcomes for infants with congenital heart disease (CHD), the most common birth defect, affecting 1 in 100 live births. In the first year of life, African Americans are 1.4 times more likely and Hispanics are 1.7 times more likely to die due to CHD than Whites. However, no one knew why race affected those outcomes. source https://medicalxpress.com/news/2022-08-pediatric-cardiologists-uncover-racial-disparity.html

Therapeutic viruses help turbocharge the immune system against cancer

The immune system has evolved to safeguard the body from a wildly diverse range of potential threats. Among these are bacterial diseases, including plague, cholera, diphtheria and Lyme disease, and viral contagions such as influenza, Ebola virus and SARS CoV-2. source https://medicalxpress.com/news/2022-08-therapeutic-viruses-turbocharge-immune-cancer.html

Some cancer immunotherapy treatments may damage fertility

Researchers have discovered that some immunotherapy treatments used to treat cancer can cause fertility damage. source https://medicalxpress.com/news/2022-08-cancer-immunotherapy-treatments-fertility.html

Rapid eye movements in sleeping mice match where they are looking in their dreams, new research finds

Does rapid eye movement during sleep reveal where you're looking at in the scenery of dreams, or are they simply the result of random jerks of our eye muscles? Since the discovery of REM sleep in the early 1950s, the significance of these rapid eye movements has intrigued and fascinated scores of scientists, psychologists and philosophers. REM sleep, as the name implies, is a period of sleep when your eyes move under your closed eyelids. It's also the period when you experience vivid dreams. source https://medicalxpress.com/news/2022-08-rapid-eye-movements-mice.html

New drug candidate developed to treat type 2 diabetes

A team of researchers from Helmholtz Munich, the German Center for Diabetes Research (DZD) and Novo Nordisk have developed a new hormone combination for the future treatment of type 2 diabetes. The scientists have combined the blood sugar-reducing effects of the drugs tesaglitazar and GLP-1 (Glucagon-like peptide-1) in a new and highly effective drug. The advantage is that, by combining tesaglitazar with GLP-1, the tesaglitazar only enters tissue that contains GLP-1 receptors. This reduces the adverse effects of tesaglitazar while increasing the effects on sugar metabolism. The new drug has already been successfully tested in animal studies. The findings were published in Nature Metabolism. source https://medicalxpress.com/news/2022-08-drug-candidate-diabetes.html

Next-generation neural probe leads to expanded understanding of the brain

A newly developed neural probe with an unprecedented number of micro-LEDs and recording sites integrated on the same neural device is enabling neuroscientists to gain new knowledge into how the brain operates. The 128 μLEDs and 256 recording electrodes on the hectoSTAR probe allow neuroscientists to track interactions across different regions of the brain. source https://medicalxpress.com/news/2022-08-next-generation-neural-probe-brain.html

Low job control a risk factor for suicidal behavior

Men working in occupations featuring low demands and low control over their own work situation are at elevated risk for suicide attempts and suicide. In jobs with high demands and high control, the risk is lower. This is shown in a study from the University of Gothenburg. source https://medicalxpress.com/news/2022-08-job-factor-suicidal-behavior.html

Cardiac arrest survival rate rising in Sweden

Sudden cardiac arrest affects some 10,000 people in Sweden annually. Saving them is a race against the clock, and the actions of bystanders who can perform cardiopulmonary resuscitation (CPR) and use a defibrillator are entirely crucial. Three in four events occur as people go about their everyday lives, while only one in four takes place in hospital. source https://medicalxpress.com/news/2022-08-cardiac-survival-sweden.html

Moderna sues Pfizer, BioNTech for COVID-19 vaccine patent infringement

Moderna said Friday it is suing rival vaccine makers Pfizer and BioNTech, alleging the partners infringed on its patents in developing their shot for COVID-19. source https://medicalxpress.com/news/2022-08-moderna-sues-pfizer-biontech-covid-.html

Long COVID costs Australia millions of working days

Long COVID has already cost the Australian economy three million working days this year, according to a government analysis seen by AFP Friday, significantly worsening the country's acute labor shortages. source https://medicalxpress.com/news/2022-08-covid-australia-millions-days.html

Simple rubber band fix improves surgical mask seal to N95 levels, study shows

Throughout the COVID-19 pandemic and when maximum protection is needed against air-born infections, the N95 respirator has remained the gold standard of personal protective equipment. However, it is also much more difficult to produce and obtain than a standard surgical mask. source https://medicalxpress.com/news/2022-08-simple-rubber-band-surgical-mask.html

Novel blood test helps evaluate severity in pulmonary arterial hypertension, a rare lung disease

Researchers at the National Institutes of Health have found that a novel blood test can be used to easily evaluate disease severity in patients with pulmonary arterial hypertension (PAH) and predict survivability. PAH is a rare, life-threatening condition that causes unexplained high blood pressure in the lungs. In early clinical studies, the researchers showed the test to significantly improve upon conventional tests, some of which use invasive tools. source https://medicalxpress.com/news/2022-08-blood-severity-pulmonary-arterial-hypertension.html

Study highlights lifelong benefits of statin therapy

Stopping statin treatment early could substantially reduce lifetime protection against heart disease since a large share of the benefit occurs later in life. That's the finding of a modeling study presented at ESC Congress 2022. source https://medicalxpress.com/news/2022-08-highlights-lifelong-benefits-statin-therapy.html

Smoking is even more damaging to the heart than previously thought

Smokers have weaker hearts than non-smokers, according to research presented at ESC Congress 2022. The study found that the more people smoked, the worse their heart function became. Some function was restored when people kicked the habit. source https://medicalxpress.com/news/2022-08-heart-previously-thought.html

Study demonstrates clinical, financial impact of patient exposure to ill healthcare worker in long-term care facility

A study conducted by researchers in Japan shows that the presence of one ill healthcare worker in a long-term care facility led to respiratory infections among 17 patients and more than $12,000 in total medical costs. Findings from the study, published today in the American Journal of Infection Control (AJIC), suggest that addressing the causative factors for such exposures is critical to help prevent infectious disease outbreaks in similar facilities. source https://medicalxpress.com/news/2022-08-clinical-financial-impact-patient-exposure.html

Legalizing recreational cannabis in the U.S. has increased frequency of use by 20%

A new study published in the scientific journal Addiction has found that the legalization of recreational cannabis in U.S. states appears to have caused a 20% average increase in cannabis use frequency in those states. source https://medicalxpress.com/news/2022-08-legalizing-recreational-cannabis-frequency.html

Octogenarians should walk 10 minutes a day to prolong life

One hour of walking per week is associated with greater longevity in people aged 85 years and above, according to research presented at ESC Congress 2022. source https://medicalxpress.com/news/2022-08-octogenarians-minutes-day-prolong-life.html

Using digital media to relax is related to lower-quality parenting

Caregivers who consume digital media for relaxation are more likely to engage in negative parenting practices, according to a new multinational study. source https://medicalxpress.com/news/2022-08-digital-media-lower-quality-parenting.html

Study: Need for more research to elucidate factors in health care access inequities

Despite improved access to health care, racial and ethnic minority populations still have disparate access compared to non-Hispanic Whites, according to a new study published in Obesity journal. source https://medicalxpress.com/news/2022-08-elucidate-factors-health-access-inequities.html

Insufficient sleep in teenagers is associated with overweight and obesity

Adolescents who sleep less than eight hours a night are more likely to be overweight or obese compared to their peers with sufficient sleep, according to research presented at ESC Congress 2022. Shorter sleepers were also more likely to have a combination of other unhealthy characteristics including excess fat around the middle, elevated blood pressure, and abnormal blood lipid and glucose levels. source https://medicalxpress.com/news/2022-08-insufficient-teenagers-overweight-obesity.html

Survey finds demand for cosmetic surgery, driven by women under 45, surged after the pandemic

After the stress of the COVID-19 pandemic, a new national survey called the Inaugural ASPS Insights and Trends Report: Cosmetic Surgery 2022 finds many Americans are now investing in themselves through cosmetic procedures, despite an uncertain economy. The American Society of Plastic Surgeons polled member surgeons nationwide and found more than three-quarters of cosmetic-focused plastic surgery practices are seeing more business than before the pandemic, with nearly 30 percent reporting their business has at least doubled. source https://medicalxpress.com/news/2022-08-survey-demand-cosmetic-surgery-driven.html

Psychotic symptoms in children may have a genetic cause

A 6-year-old boy began hearing voices coming from the walls and the school intercom telling him to hurt himself and others. He saw ghosts, aliens in trees, and colored footprints. Joseph Gonzalez-Heydrich, MD, a psychiatrist at Boston Children's Hospital, put him on antipsychotic medications and the frightening hallucinations stopped. Another child, at age 4, had hallucinations with monsters, a big black wolf, spiders, and a man with blood on his face. source https://medicalxpress.com/news/2022-08-psychotic-symptoms-children-genetic.html

News addiction is linked to not only poor mental well-being but physical health too, new study shows

People with an obsessive urge to constantly check the news are more likely to suffer from stress, anxiety, and physical ill health, finds a new study published in the peer-reviewed journal Health Communication. source https://medicalxpress.com/news/2022-08-news-addiction-linked-poor-mental.html

Air pollution is associated with heart attacks in non-smokers

Research presented at ESC Congress 2022 supports a causal relationship between air pollution and heart attacks since smokers, who already inhale smoke, were unaffected by dirty air. source https://medicalxpress.com/news/2022-08-air-pollution-heart-non-smokers.html

Autism diagnosis impacted by men and women's different emotional needs

A new study published by a team of psychologists suggests that the diagnosis of autism could be improved by considering the differences between how women and men experience and act upon their emotions. source https://medicalxpress.com/news/2022-08-autism-diagnosis-impacted-men-women.html

Risk of premature death in adulthood influenced by patterns of early childhood adversity, study suggests

Poverty, combined with other types of adversity in early childhood, is associated with greater chances of premature death in adulthood, compared to other adverse childhood experiences, according to a study of more than 46,000 people by researchers at the National Institutes of Health. source https://medicalxpress.com/news/2022-08-premature-death-adulthood-patterns-early.html

Researchers release largest dataset of Neuropixels recordings ever collected

From 300,000 mouse neurons, scientists hope to glean how the brain drives behavior. A newly released publicly available dataset is the largest of its kind and represents billions of split-second electrical pulses that comprise the brain's language of information. From this massive collection of cellular activity, scientists hope to decode the neural computations that underlie behavior. source https://medicalxpress.com/news/2022-08-largest-dataset-neuropixels.html

Surprising culprit worsens stroke, TBI damage

In the aftermath of a stroke or TBI, a group of amino acids that typically support brain function contribute significantly to the brain destruction that can follow both these injuries, scientists report. source https://medicalxpress.com/news/2022-08-culprit-worsens-tbi.html

Non-steroidal anti-inflammatory drugs linked with heart failure in patients with diabetes

Short-term use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a first-time hospitalization for heart failure in patients with type 2 diabetes, according to research presented at ESC Congress 2022. source https://medicalxpress.com/news/2022-08-non-steroidal-anti-inflammatory-drugs-linked-heart.html

Skipping breakfast may increase chance of kids and teens developing psychosocial health problems

Young people who eat healthy breakfasts at home have better psychosocial health, shows a recent study in Frontiers in Nutrition. While previous research has reported the important role of a nutritious breakfast, this is the first study to look at the reported effects of whether kids eat breakfast, as well as where and what they eat. These results provide valuable insights and recommendations for parents and their children. source https://medicalxpress.com/news/2022-08-breakfast-chance-kids-teens-psychosocial.html

If You're 'Diet-Resistant', Exercise May Be Key to Weight Loss

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New research suggests there's a category of "diet-resistant" people who need to work out and watch what they eat to lose weight. source https://www.webmd.com/diet/obesity/news/20220822/are-you-among-the-diet-resistant-workouts-may-be-key-to-weight-loss?src=RSS_PUBLIC

Eating for health and sustainability is cheaper for the household budget (and better for the planet)

New research on household family shopping baskets from the University of Wollongong has confirmed that eating a diet based on whole and fresh foods is still the cheapest option for most Australian families—despite CPI price hikes. source https://medicalxpress.com/news/2022-08-health-sustainability-cheaper-household-planet.html

An apple a day on doctors' orders keeps ill health away

Fresh fruit and vegetables prescribed by doctors could be an effective way to improve the health of Australians with type 2 diabetes, according to a new study published today in the Journal of Nutrition. source https://medicalxpress.com/news/2022-08-apple-day-doctors-ill-health.html

Dental biorhythm is associated with adolescent weight gain

Research led by the University of Kent has discovered evidence of a biorhythm in human primary teeth that is associated with weight gain during adolescence. source https://medicalxpress.com/news/2022-08-dental-biorhythm-adolescent-weight-gain.html

New findings reveal how recovery progresses following inflammation triggered by injury or illness

Inflammation is the body's first line of defense, occurring as droves of immune cells rush to the site of injury or acute illness to make repairs and stem further damage. source https://medicalxpress.com/news/2022-08-reveal-recovery-inflammation-triggered-injury.html

Myocarditis risk significantly higher after COVID-19 infection vs. after a COVID-19 vaccine

In a detailed analysis of nearly 43 million people, ages 13 and older, who received at least one dose of a COVID-19 vaccine in England, the risk of myocarditis in unvaccinated individuals after COVID-19 infection was at least 11 times higher compared to people who developed myocarditis after receiving a COVID-19 vaccine or booster dose between December 1, 2020 and December 15, 2021, according to new research published today in the American Heart Association's flagship, peer-reviewed journal Circulation. source https://medicalxpress.com/news/2022-08-myocarditis-significantly-higher-covid-infection.html

How did the early COVID-19 pandemic affect cancer survivors?

Recent research indicates that during the first year of the COVID-19 pandemic, the proportion of working-aged U.S. adults without health insurance did not change despite increases in unemployment, and the prevalence of unhealthy behaviors decreased. The findings, which were published in CANCER, pertained to individuals with and without a history of cancer. source https://medicalxpress.com/news/2022-08-early-covid-pandemic-affect-cancer.html

Food allergies can be reversed in mice by targeting the microbiome

Although many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal consequences. A bacterial compound called butyrate that's made by healthy microbiomes has shown promise against allergic reactions in lab tests, but it's nasty to take orally. Today, scientists describe a more palatable way to deliver this compound and report that their "polymeric micelles" are effective against peanut allergies in mice. The treatment could someday counteract many types of food allergies and inflammatory diseases. source https://medicalxpress.com/news/2022-08-food-allergies-reversed-mice-microbiome.html

Polio in US, UK and Israel reveals rare risk of oral vaccine

For years, global health officials have used billions of drops of an oral vaccine in a remarkably effective campaign aimed at wiping out polio in its last remaining strongholds—typically, poor, politically unstable corners of the world. source https://medicalxpress.com/news/2022-08-polio-uk-israel-reveals-rare.html

Scientists find surprising link between mitochondrial DNA and increased atherosclerosis risk

Mitochondria are known as cells' powerhouses, but mounting evidence suggests they also play a role in inflammation. Scientists from the Salk Institute and UC San Diego published new findings in Immunity on July 26, 2022, where they examined human blood cells and discovered a surprising link between mitochondria, inflammation and DNMT3A and TET2—two genes that normally help regulate blood cell growth but, when mutated, are associated with an increased risk of atherosclerosis. source https://medicalxpress.com/news/2022-07-scientists-link-mitochondrial-dna-atherosclerosis.html

DR Congo investigates suspected Ebola case

The Democratic Republic of Congo is investigating a suspected case of Ebola in its violence-wracked east, the World Health Organization said Saturday, just weeks after the end of a previous epidemic. source https://medicalxpress.com/news/2022-08-dr-congo-ebola-case.html

Cuba's first monkeypox case recorded in Italian tourist

Cuba reported its first case of monkeypox Saturday in an Italian tourist who is in "critical" condition, the health ministry said. source https://medicalxpress.com/news/2022-08-cuba-monkeypox-case-italian-tourist.html

Rat race: What rodent drivers can teach us about mental health

The girls can't hide their excitement as they're brought out to the racing arena. source https://medicalxpress.com/news/2022-08-rat-rodent-drivers-mental-health.html

Indonesia records first case of monkeypox virus

Indonesia has recorded its first case of monkeypox in a 27-year-old man who returned from travelling overseas, the country's health ministry said on Saturday. source https://medicalxpress.com/news/2022-08-indonesia-case-monkeypox-virus.html

Wendy's pulls lettuce from sandwiches amid E. coli outbreak

The fast-food chain Wendy's says it is pulling lettuce from sandwiches in its restaurants in Michigan, Ohio and Pennsylvania after people eating them there reported falling ill. source https://medicalxpress.com/news/2022-08-wendy-lettuce-sandwiches-coli-outbreak.html

Chronic neuropsychiatric symptoms confirmed after COVID-19

Chronic neuropsychiatric symptoms are observed following COVID-19 infection, although self-reported symptoms are not associated with quantitative dysfunction, according to a study published in the October issue of Brain, Behavior & Immunity: Health. source https://medicalxpress.com/news/2022-08-chronic-neuropsychiatric-symptoms-covid-.html

New study shows patient preference for medical cannabis products in the absence of clinical guidelines

Due to a lack of publicly available data, understanding what products medical cannabis patients use for various conditions has mostly come from survey responses. In a new study, USC Schaeffer Center researchers established a clearer picture by analyzing point-of-sale data from nearly 17,000 patients who made more than 80,000 purchases as part of the New York state medical cannabis program. source https://medicalxpress.com/news/2022-08-patient-medical-cannabis-products-absence.html

Transplant candidates' thoughts about tradeoffs of shorter wait time for lower quality kidneys

Approximately 20% of deceased donor kidneys are discarded each year in the United States, but a recent study in CJASN indicates that many patients on the transplant waitlist would prefer accepting such lower quality kidneys in return for a shorter waiting time. source https://medicalxpress.com/news/2022-08-transplant-candidates-thoughts-tradeoffs-shorter.html

Anti-vax group in Europe thrives online, thwarts tech effort

Troubled by the number of unvaccinated COVID-19 patients showing up at his hospital, the French doctor logged on to Facebook and uploaded a video urging people to get vaccinated. source https://medicalxpress.com/news/2022-08-anti-vax-group-europe-online-thwarts.html

FDA targets illegal nicotine gummies in new warning letter

Federal regulators on Thursday issued a first-of-a-kind warning to the maker of nicotine gummies, saying the illegal candies pose a growing risk to teenagers and younger children. source https://medicalxpress.com/news/2022-08-fda-illegal-nicotine-gummies-letter.html

Brain-eating amoeba suspected in 2nd Midwest death

A child likely died from a rare infection caused by a brain-eating amoeba after swimming in an eastern Nebraska river, health officials said, making it the second such probable death in the Midwest this summer and raising the question of whether climate change is playing a role. source https://medicalxpress.com/news/2022-08-brain-eating-amoeba-2nd-midwest-death.html

Steepest annual rise in advanced cervical cancer in US among White women

The steepest annual rise in new cases of advanced womb (cervical) cancer in the US is among White women, who are significantly less likely to have the preventive HPV (human papillomavirus) jab or to be screened for the disease, finds research published online in the International Journal of Gynecological Cancer. source https://medicalxpress.com/news/2022-08-steepest-annual-advanced-cervical-cancer.html

First real-world study gives detailed new insights into when people with COVID-19 are infectious

A new study of 57 people with mild COVID-19 estimates how long people are infectious for and when they can safely leave isolation. source https://medicalxpress.com/news/2022-08-real-world-insights-people-covid-infectious.html

Researchers examine link between pesticides and thyroid cancer risk in Central California area

In single pollutant models and within a 20-year period, 10 out of 29 reviewed pesticides were associated with thyroid cancer, including several of the most widely used ones in the U.S. These included paraquat dichloride, glyphosate and oxyfluorfen. source https://medicalxpress.com/news/2022-08-link-pesticides-thyroid-cancer-central.html

How immune cells overcome exhaustion

Researchers have discovered a new population of immune cells that are critical in maintaining the immune response against chronic infections and cancer. This population of T cells also mediates the response to immunotherapy using checkpoint inhibitors. The discovery may explain why immunotherapy fails in some people and could lead to the development of more effective new therapies for cancer or severe viral infections. source https://medicalxpress.com/news/2022-08-immune-cells-exhaustion.html

Study unveils a global dysregulation of dopamine in mice with chronic inflammatory pain

Over the past decades, many neuroscientists have investigated how the mammalian brain modulates pain, trying to uncover the neural mechanisms underpinning chronic pain. Chronic pain is pain in specific parts of the body, that persists for long periods of time, including arthritis, back pain, neck pain or other forms of pain. source https://medicalxpress.com/news/2022-08-unveils-global-dysregulation-dopamine-mice.html

Anger as US court says teen not 'mature' enough for abortion

An appeals court in Florida has upheld a ruling that a 16-year-old girl is not "sufficiently mature" enough to get an abortion—a decision that sparked the ire of some US lawmakers. source https://medicalxpress.com/news/2022-08-anger-court-teen-mature-abortion.html

Considering genetic risk in prostate cancer referrals could lead to earlier diagnosis

Men at the highest risk for prostate cancer could be fast-tracked for investigation if their genetic risk was considered in general practice, new research has concluded. source https://medicalxpress.com/news/2022-08-genetic-prostate-cancer-referrals-earlier.html

Attitudes toward mandatory COVID-19 vaccination in Germany

It has become obvious that sufficiently high immunity to COVID-19 cannot be achieved in Germany through voluntary vaccination alone. On this background, Thomas Rieger and Carsten Schröder from the German Institute for Economic Research, Berlin, together with Christoph Schmidt-Petri from the Karlsruhe Institute of Technology, investigated the acceptance of a policy of general mandatory vaccination against COVID-19. The scientists also investigated the questions of which population groups are supportive of such a measure, which ones are opposed, and what their reasons are, respectively. source https://medicalxpress.com/news/2022-08-attitudes-mandatory-covid-vaccination-germany.html

GlyNAC supplementation reverses aging hallmarks in aging humans

A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC—a combination of glycine and N-acetylcysteine—improves many age-associated defects in older humans and powerfully promotes healthy aging. This is relevant because until now, there have been no solutions toward improving many of these age-related declines in people. source https://medicalxpress.com/news/2022-08-glynac-supplementation-reverses-aging-hallmarks.html

A step closer to a low toxicity treatment for childhood leukemia

Newly published research carried out using synthetic human bone marrow cells is paving the way for the development of safer and kinder treatments for children with leukemia. source https://medicalxpress.com/news/2022-08-closer-toxicity-treatment-childhood-leukemia.html

New gene variant that protects against coronary heart disease uncovered

A variant typical of the Finnish population that protects against heart diseases was identified in the FinnGen genomic study coordinated by the University of Helsinki. The risk of developing heart diseases is roughly one-fifth lower in carriers of the variant compared to the population on average. source https://medicalxpress.com/news/2022-08-gene-variant-coronary-heart-disease.html

Researchers identify an Achilles' heel in neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy. source https://medicalxpress.com/news/2022-08-achilles-heel-neuroblastoma.html

Intranasal vaccination produces potent systemic immunity against HIV and SARS-CoV-2 in animal models

Even though most viruses cause infection directly through mucosal cells, the vast majority of vaccines are administered intramuscularly in a cellular mismatch that doesn't always produce optimum immunity. source https://medicalxpress.com/news/2022-08-intranasal-vaccination-potent-immunity-hiv.html

More than 150 children dead in Zimbabwe measles outbreak

A measles outbreak in Zimbabwe has killed at least 157 children, with more than 2,000 infections reported across the country, the government said on Tuesday. source https://medicalxpress.com/news/2022-08-children-dead-zimbabwe-measles-outbreak.html

Genomics empowers vaccine makers to tackle shapeshifting bacteria

A pioneering genomic surveillance study has provided the clearest picture yet of the arms race between Streptococcus pneumoniae, the bacterium responsible for a range of illnesses such as pneumonia and meningitis, and the vaccines designed to protect against the most dominant types. A strain called GPSC10 was found to be a particular threat, due to its increased virulence, ability to transform its structure to evade vaccines and its resistance to several common antibiotics. source https://medicalxpress.com/news/2022-08-genomics-empowers-vaccine-makers-tackle.html

New study indicates people with current cancer diagnosis may face severe complications from COVID-19

A new study has found that a current cancer diagnosis posed a significant risk for severe outcomes during the first two years of the COVID-19 pandemic, including ICU admission and death. UC Davis Comprehensive Cancer Center researchers took part in the study, which was published this week in Cancer Epidemiology, Biomarkers & Prevention. source https://medicalxpress.com/news/2022-08-people-current-cancer-diagnosis-severe.html

Peptide delivered by nasal spray can reduce seizure activity, protect neurons in Alzheimer's, epilepsy

A novel peptide augments the brain's natural mechanism to help prevent seizures and protect neurons in research models of both Alzheimer's and epilepsy, scientists report. source https://medicalxpress.com/news/2022-08-peptide-nasal-seizure-neurons-alzheimer.html

Targeted cancer vaccines eliminate tumors and prevent recurrence in mice

Researchers around the world have been working for years on developing vaccines against different types of cancer, but without much success. Now, Tufts School of Engineering researchers think they have found one that does work. They have devised a method of targeting cancer in mice with a vaccine that is so strong and precise, it eliminates tumors and even prevents their recurrence. source https://medicalxpress.com/news/2022-08-cancer-vaccines-tumors-recurrence-mice.html

A virtual trip to the museum can improve the health of seniors stuck at home

Scientists have long known that social isolation is associated with a number of health problems, including increased risks for stroke and heart disease, as well as mental decline and even premature death. The risks are especially acute for older adults, who are more likely to be socially isolated and lonely. The coronavirus pandemic only exacerbated the problem due to the need for social distancing, particularly to protect the health of the world's elderly population. source https://medicalxpress.com/news/2022-08-virtual-museum-health-seniors-stuck.html

New wearable sensor detects even more compounds in human sweat

If you have ever had your blood drawn, whether to check your cholesterol, kidney function, hormone levels, blood sugar, or as part of a general checkup, you might have wondered why there is not an easier, less painful way. source https://medicalxpress.com/news/2022-08-wearable-sensor-compounds-human.html

Why it's important to tell people that monkeypox is predominantly affecting gay and bisexual men

Monkeypox virus, or MPXV, is an emerging threat to public health. The World Health Organization recently declared the current outbreak a global public health emergency. source https://medicalxpress.com/news/2022-08-important-people-monkeypox-predominantly-affecting.html

Why do I wake up thirsty?

If you wake up in the morning feeling thirsty, you might be dehydrated. source https://medicalxpress.com/news/2022-08-thirsty.html

'Like Wildfire': Covid cases skyrocket on Marshall Islands

A health disaster has been declared on the Marshall Islands after the fast-spreading COVID variant Omicron infected more than a tenth of residents in the capital Majuro in one week. source https://medicalxpress.com/news/2022-08-wildfire-covid-cases-skyrocket-marshall.html

Southern hemisphere to get first mRNA vaccine facility

Covid-19 vaccine maker Moderna announced Monday that it will open an mRNA vaccine manufacturing facility in the Australian city of Melbourne, a first for the southern hemisphere. source https://medicalxpress.com/news/2022-08-southern-hemisphere-mrna-vaccine-facility.html

1 in 3 parents worry that school traffic is a danger for kids

For some elementary and middle schoolers, one of the most nerve-wracking parts of the school day starts before the first bell even rings: morning drop off. source https://medicalxpress.com/news/2022-08-parents-school-traffic-danger-kids.html

Research shows it's how often you do it, not how much

So… should I exercise a little bit every day, or exercise for longer once a week? source https://medicalxpress.com/news/2022-08-research-shows-it-how-often.html

Four Cruise Lines to Drop COVID Vaccination Requirements

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Four major cruise lines are dropping their COVID-19 vaccination requirements for some sailings next month, according to USA Today. source https://www.webmd.com/lung/news/20220814/four-cruise-lines-to-drop-covid-vaccination-requirements?src=RSS_PUBLIC

Scotland first country to ensure access to free period products

Scotland will on Monday become the first country in the world to ensure universal access to free period products following the passing of landmark legislation in 2020. source https://medicalxpress.com/news/2022-08-scotland-country-access-free-period.html

UMHS Application Process Walkthrough Livestream

Join UMHS Director of Enrollment Management, Shyam Dharia, for a complete walkthrough of our application process. source https://www.youtube.com/watch?v=0VTMvKRgRvk

Do Psychiatrists Go To Medical School?

Do Psychiatrists Go To Medical School? https://www.umhs-sk.org/blog/become-a-psychiatrist#go_med_school https://www.youtube.com/playlist?list=PL7_-WDU1Vnt1KRO8Hs6Y-5LbGpLipkVIY #psychiatrist #psychiatry #premedstudent #medicalschool #medicalcareer #caribbeanmedicalschools source https://www.youtube.com/watch?v=doJG2TKHpjE

New chip could make treating metastatic cancer easier and faster

Researchers at the Georgia Institute of Technology have found a detection method that could revolutionize cancer treatment by showing how cancers metastasize and what stage they are. source https://medicalxpress.com/news/2022-08-chip-metastatic-cancer-easier-faster.html

Plant-Based Diets and Your Cholesterol

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A plant-based diet might help bring your cholesterol numbers down, along with your chances of heart disease. source https://www.webmd.com/cholesterol-management/features/plant-based-diets-and-cholesterol?src=RSS_PUBLIC

Psychiatry Subspecialties - What are the Subspecialties of Psychiatry Medicine?

Psychiatry Subspecialties - What are the subspecialties of Psychiatry Medicine? https://www.umhs-sk.org/blog/become-a-psychiatrist#subspecialties https://www.youtube.com/playlist?list=PL7_-WDU1Vnt1KRO8Hs6Y-5LbGpLipkVIY #psychiatrist #psychiatry #premedstudent #medicalcareer #caribbeanmedicalschools source https://www.youtube.com/watch?v=-FQujPwT-iU

Psychiatry vs Psychology - What's the Difference between a Psychiatrist and a Psychologist

Psychiatry vs Psychology - What's the Difference between a Psychiatrist and a Psychologist https://www.umhs-sk.org/blog/become-a-psychiatrist#psychology_difference https://www.youtube.com/playlist?list=PL7_-WDU1Vnt1KRO8Hs6Y-5LbGpLipkVIY #psychiatrist #psychiatry #psychiatryvspsychology #premed source https://www.youtube.com/watch?v=_GF8Ccg_0gs

Germany: EU could OK combined COVID vaccines next month

Germany's health minister said Friday that European Union drug regulators may authorize the use of vaccines that are each effective against two variants of the coronavirus. source https://medicalxpress.com/news/2022-08-germany-eu-combined-covid-vaccines.html

Breakthrough in search for tinnitus cure

After 20 years searching for a cure for tinnitus, researchers at the University of Auckland are excited by 'encouraging results' from a clinical trial of a mobile-phone-based therapy. source https://medicalxpress.com/news/2022-08-breakthrough-tinnitus.html

More than 1 in 4 children hospitalized with COVID-19 or MIS-C have lingering complications more than two months later

In one of the largest follow-up studies to date, involving 25 pediatric hospitals, more than a quarter of children and adolescents hospitalized with coronavirus infection early in the pandemic still had health problems two to four months later, either persisting symptoms or activity impairment. The study, led by Boston Children's Hospital, is published August 12 in the journal Pediatrics. source https://medicalxpress.com/news/2022-08-children-hospitalized-covid-mis-c-lingering.html

Mask mandates return in New Delhi as COVID-19 cases rise

The Indian capital reintroduced public mask mandates on Thursday as COVID-19 cases continue to rise across the country. source https://medicalxpress.com/news/2022-08-mask-mandates-delhi-covid-cases.html

Africa CDC in 'advanced' talks to obtain monkeypox vaccines

Africa's public health agency says the continent of 1.3 billion people still does not have a single dose of the monkeypox vaccine, but "very advanced discussions" are underway with at least two partners. source https://medicalxpress.com/news/2022-08-africa-cdc-advanced-monkeypox-vaccines.html

Study finds that sound plus electrical body stimulation has potential to treat chronic pain

A University of Minnesota Twin Cities-led team has found that electrical stimulation of the body combined with sound activates the brain's somatosensory or "tactile" cortex, increasing the potential for using the technique to treat chronic pain and other sensory disorders. The researchers tested the non-invasive technique on animals and are planning clinical trials on humans in the near future. source https://medicalxpress.com/news/2022-08-electrical-body-potential-chronic-pain.html

Chinese medical portal censored after doubting herbal 'COVID remedy'

A popular Chinese medical information site has been censored by authorities for "violation of relevant laws and regulations", months after its criticism of a government-backed herbal COVID-19 treatment sent shares in a pharmaceutical giant tumbling. source https://medicalxpress.com/news/2022-08-chinese-medical-portal-censored-herbal.html

Experts see Canada's euthanasia laws as threat to disabled

Alan Nichols had a history of depression and other medical issues, but none were life-threatening. When the 61-year-old Canadian was hospitalized in June 2019 over fears he might be suicidal, he asked his brother to "bust him out" as soon as possible. source https://medicalxpress.com/news/2022-08-experts-canada-euthanasia-laws-threat.html

BCG vaccine prevents tuberculosis in young children, but not adults: study

Amid longstanding debate on the effectiveness of the tuberculosis vaccine, a new study suggests that the vaccine is protective against TB in children under 5, but adolescents and adults in high-burden countries may need additional protection to maintain immunity beyond childhood. source https://medicalxpress.com/news/2022-08-bcg-vaccine-tuberculosis-young-children.html

Experimental drug reduces risk of death from blood vessel rupture in mice

An experimental drug therapy protects mice from sudden death due to the rupture of a major blood vessel in the abdomen, according to a study from researchers at Washington University School of Medicine in St. Louis. source https://medicalxpress.com/news/2022-08-experimental-drug-death-blood-vessel.html

Scientists identify pathway to curb spread of brain cancer

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models. The findings, published in Nature Cell Biology, have led to a clinical trial that could offer new hope to patients with glioblastoma, the most common form of brain cancer in adults that kills hundreds of thousands of people worldwide each year. source https://medicalxpress.com/news/2022-08-scientists-pathway-curb-brain-cancer.html

New antibiotic resistance genes identified in tuberculosis

A massive analysis of more than 10,000 different Mycobacterium tuberculosis bacteria isolates from 23 countries has revealed new genes associated with resistance to 13 first- and second-line new and repurposed antibiotics. The work, carried out by Comprehensive Resistance Prediction for Tuberculosis: an International Consortium (CRyPTIC), is described in two new papers publishing August 11th in the open-access journal PLOS Biology. source https://medicalxpress.com/news/2022-08-antibiotic-resistance-genes-tuberculosis.html

Study identifies immune regulator as critical contributor to stomach cancer development

Researchers aim to beat stomach cancer at its own game by identifying modulators of the innate immune system that drive it and applying the brakes before cancer takes hold. In 2021, Professor Brendan Jenkins and Dr. Ruby Dawson challenged conventional thinking about how stomach cancer forms—the answers have created a paradigm shift in scientific thinking around how the immune system contributes to the development of stomach cancer. source https://medicalxpress.com/news/2022-08-immune-critical-contributor-stomach-cancer.html

Major test of first possible Lyme vaccine in 20 years begins

Researchers are seeking thousands of volunteers in the U.S. and Europe to test the first potential vaccine against Lyme disease in 20 years—in hopes of better fighting the tick-borne threat. source https://medicalxpress.com/news/2022-08-major-lyme-vaccine-years.html

Efforts to save money on prescription drugs associated with increased stroke risk for seniors

Atrial fibrillation (AF) is a major risk factor for stroke, and for decades the anticoagulant warfarin was the standard treatment for lowering that hazard. However, numerous drug and food interactions make warfarin burdensome for patients. A new class of drugs—non–vitamin K antagonist oral anticoagulants (NOACs)—have emerged as an alternative that is more effective as well as less burdensome. But these drugs also come with a higher price tag than generic warfarin. source https://medicalxpress.com/news/2022-08-efforts-money-prescription-drugs-seniors.html

Locally supportive climates may do little to aid mental health for LGBTQ+ youth amidst broader societal stigma

As rates of youth mental health issues soar in the United States, new research offers surprising insights into how social factors affect trends for LGBTQ+ youth, who are especially at risk due to the harmful effects of discrimination. source https://medicalxpress.com/news/2022-08-locally-climates-aid-mental-health.html

Research shows parents are 'winging it' on their kids' mobile use

As many parents will attest, children and teens' mobile use is a significant source of family arguments. source https://medicalxpress.com/news/2022-08-parents-winging-kids-mobile.html

Legalized cannabis linked to fewer synthetic cannabinoid poisonings

Synthetic cannabinoids, dangerous designer drugs known by such street names as K2, Spice or AK-47, appear to have less appeal in states that have legalized the natural form of cannabis. source https://medicalxpress.com/news/2022-08-legalized-cannabis-linked-synthetic-cannabinoid.html

Early diagnosis of lung cancer among younger vs. older adults: widening disparities in the era of lung cancer screening

Younger patients with lung cancer are significantly more likely than older patients to be diagnosed with later stages of disease, illustrating the need to develop strategies to increase the early detection of lung cancer among younger patients who are currently ineligible for lung cancer screening. The research was presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna, Austria. source https://medicalxpress.com/news/2022-08-early-diagnosis-lung-cancer-younger.html

IASLC early detection and screening committee to report on global obstacles to lung cancer screening

Lung cancer screening with low dose CT technology has been shown to be effective in reducing mortality associated with lung cancer but current data on the status of lung cancer screening data in low- and middle-income countries is scarce, often opinion-based or is limited. source https://medicalxpress.com/news/2022-08-iaslc-early-screening-committee-global.html

Phase 2 study of lung cancer gene panel testing demonstrates cytological specimens accurate

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples. source https://medicalxpress.com/news/2022-08-phase-lung-cancer-gene-panel.html

Study discloses clinical-relevant intertumoral heterogeneity of NSCLCs driven by MET exon 14 skipping

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping. source https://medicalxpress.com/news/2022-08-discloses-clinical-relevant-intertumoral-heterogeneity-nsclcs.html

New flavored nicotine gums, lozenges, and gummies rank second among nicotine products used by US teens

Flavored oral nicotine products, which contain no tobacco but are not FDA-approved to help people quit smoking, are increasingly marketed and sold in the U.S., but researchers have never measured their use among U.S. teens. source https://medicalxpress.com/news/2022-08-flavored-nicotine-gums-lozenges-gummies.html

Scientists revive cells and organs in dead pigs

Scientists announced Wednesday they have restored blood flow and cell function throughout the bodies of pigs that were dead for an hour, in a breakthrough experts say could mean we need to update the definition of death itself. source https://medicalxpress.com/news/2022-08-scientists-revive-cells-dead-pigs.html

Long COVID symptoms affects one in eight, study suggests

One in eight people who get coronavirus develop at least one symptom of long COVID, one of the most comprehensive studies on the condition to date suggested on Thursday. source https://medicalxpress.com/news/2022-08-covid-symptoms-affects.html

Pfizer in talks on $5 billion acquisition: media

American drugmaker Pfizer is close to a deal to purchase Global Blood Therapeutics, which manufactures a recently approved drug against sickle-cell anemia, for $5 billion, the Wall Street Journal has reported. source https://medicalxpress.com/news/2022-08-pfizer-billion-acquisition-media.html

Over 80,000 tourists trapped in 'China's Hawaii' after COVID outbreak

Over 80,000 tourists are stranded in a resort city popularly known as "China's Hawaii" after a COVID flare-up led authorities to impose strict travel restrictions. source https://medicalxpress.com/news/2022-08-tourists-china-hawaii-covid-outbreak.html

Polio fears rise in New York amid possible community spread

New York state health officials issued a more urgent call Thursday for unvaccinated children and adults to get inoculated against polio, citing new evidence of possible "community spread" of the dangerous virus. source https://medicalxpress.com/news/2022-08-polio-york.html

Most reliable estimates to date suggest one in eight COVID-19 patients develop long COVID symptoms

One in eight adults (12.7%) who are infected with SARS-CoV-2 experience long term symptoms due to COVID-19, suggests a large Dutch study published in The Lancet. source https://medicalxpress.com/news/2022-08-reliable-date-covid-patients-covid.html

Children's health will be negatively impacted by poorer fitness as global temperatures rise, new research shows

Record levels of obesity and physical inactivity among children mean they are set to bear the brunt of poorer health effects from rising global temperatures—that's the stark warning in a new comprehensive review of current studies on the topic. source https://medicalxpress.com/news/2022-08-children-health-negatively-impacted-poorer.html

Study finds new chronic rhinitis treatment could be game changer

A new study at Houston Methodist evaluating the long-term effectiveness of a minimally invasive, in-office procedure could be a game changer for individuals with chronic rhinitis, an upper-respiratory condition marked by a near-constant runny nose, post-nasal drip, congestion, sneezing, coughing, and nasal and throat itching. source https://medicalxpress.com/news/2022-08-chronic-rhinitis-treatment-game-changer.html

Preterm birth delay drugs safe for global reduction in neonatal death

Women around the world should be able to access the best medical treatments that help to delay preterm births and improve neonatal outcomes, new research suggests. source https://medicalxpress.com/news/2022-08-preterm-birth-drugs-safe-global.html

Protein that may predict future diabetes risk and death from cancer identified

New research, published in Diabetologia, suggests that people with elevated levels of the protein prostasin (mainly found in epithelial cells which line the surfaces and organs of the body) may be at higher risk of developing diabetes. source https://medicalxpress.com/news/2022-08-protein-future-diabetes-death-cancer.html

Researchers point to gap in Indigenous health equalities

A UBC Okanagan researcher is calling attention to the looming gap in health equality when it comes to Indigenous populations living off-reserve in Canada. source https://medicalxpress.com/news/2022-08-gap-indigenous-health-equalities.html

Stopping moles from turning into the deadliest type of skin cancer

In a small patch of skin no bigger than an inch, there are millions of cells all performing duties, like protecting us from bacteria and sensing temperature. A portion of them are melanocytes, a type of cell dedicated to producing melanin, the substance that gives color to our skin, eyes, and hair. If triggered by UV light from the sun, melanocytes can form moles, or beauty marks. source https://medicalxpress.com/news/2022-08-moles-deadliest-skin-cancer.html

Study finds children missing out on healthy diets at childcare

Researchers from Deakin University's Institute for Physical Activity and Nutrition (IPAN), found most childcare centers were feeding children too much refined food, such as pikelets, cakes and cupcakes, and not enough fruit and vegetables and nearly two-thirds of staff who plan their menus don't have any nutrition training. source https://medicalxpress.com/news/2022-08-children-healthy-diets-childcare.html

Who is at fault when medical software gets it wrong?

Doctors are being increasingly encouraged to rely on digital technology to guide care, but who carries the blame if doctors rely on software that makes mistakes, leading to patient harm? source https://medicalxpress.com/news/2022-08-fault-medical-software-wrong.html

Social isolation and loneliness increase the risk of death from heart attack, stroke

Social isolation and loneliness are associated with about a 30% increased risk of heart attack or stroke, or death from either, according to a new scientific statement from the American Heart Association, published today in the Journal of the American Heart Association. The statement also identifies the lack of data on interventions that may improve cardiovascular health for people who are socially isolated or lonely. source https://medicalxpress.com/news/2022-08-social-isolation-loneliness-death-heart.html

SuPAR identifies patients at high risk of blood clot formation

Blood clots are thought to occur in as many as a third of patients hospitalized with COVID-19. In many cases these clots can be deadly, such as pulmonary embolisms—blood clots that travel to the lungs. In fact, in nearly one third of patients with COVID-19, these clots led to death. source https://medicalxpress.com/news/2022-08-supar-patients-high-blood-clot.html

Arkansas panel rejects recreational marijuana ballot measure

The State Board of Election Commissioners on Wednesday blocked a proposal to legalize recreational marijuana from appearing on Arkansas' ballot this fall. source https://medicalxpress.com/news/2022-08-arkansas-panel-recreational-marijuana-ballot.html

Mobile app to help those seeking to reduce their alcohol consumption

A new smartphone app, which has been made available to the public today, has been found to be successful in helping U.K. veterans to reduce alcohol consumption. source https://medicalxpress.com/news/2022-08-mobile-app-alcohol-consumption.html

Novel drug shows promising efficacy for patients with multiple myeloma

Results of an international clinical trial co-led by researchers at Winship Cancer Institute at Emory University show potential for a novel drug to benefit patients with multiple myeloma whose disease either recurred or was resistant to three or more earlier lines of treatment. source https://medicalxpress.com/news/2022-08-drug-efficacy-patients-multiple-myeloma.html

Are persistent infections of novel coronavirus the cause of sequelae in infected hosts?

A research team, comprised of Associate Professor Tomonari Sumi of the Research Institute for Interdisciplinary Science at Okayama University and Associate Professor Kouji Harada of the Center for IT-based Education (CITE) at Toyohashi University of Technology, has developed a mathematical model of the immune response within infected hosts that considers systemic infection of a novel coronavirus (SARS-CoV-2), and demonstrated by conducting experimental computer simulations that persistent viral infections within hosts potentially cause long COVID or post-acute sequelae of COVID-19. source https://medicalxpress.com/news/2022-08-persistent-infections-coronavirus-sequelae-infected.html

Percent of Americans without health coverage hits new low

The proportion of the US population with no health insurance in the United States reached a new low in early 2022 at eight percent, President Joe Biden's administration said Tuesday. source https://medicalxpress.com/news/2022-08-percent-americans-health-coverage.html

Pandemic has put long-haul pilots in a stressful tailspin

Stress levels among commercial airline pilots have skyrocketed during the COVID-19 pandemic, putting their mental health at risk, according to a new study by the University of South Australia. source https://medicalxpress.com/news/2022-08-pandemic-long-haul-stressful-tailspin.html

Are UK children with allergies receiving consistent and adequate care?

New research in Clinical & Experimental Allergy indicates that over the past 15 years, the number of allergy clinics for children in the UK has increased 4-fold and the number of appointments has increased 7-fold. source https://medicalxpress.com/news/2022-08-uk-children-allergies-adequate.html

Does fraud victimization affect a person's long-term blood pressure?

New research published in the Journal of the American Geriatrics Society suggests that experiencing financial exploitation, fraudulent schemes, and scams may raise a person's blood pressure. The study found that fraud victimization was linked with elevated blood pressure in men, but not in women. source https://medicalxpress.com/news/2022-08-fraud-victimization-affect-person-long-term.html

SARS-CoV-2 and vaccine uptake among First Nations, Inuit and Métis peoples in urban areas

Despite prioritizing Indigenous populations for SARS-CoV-2 vaccinations, vaccine uptake was low among First Nations, Inuit and Métis Peoples in Toronto and London, Ontario, according to new research published in CMAJ (Canadian Medical Association Journal). source https://medicalxpress.com/news/2022-08-sars-cov-vaccine-uptake-nations-inuit.html

Evusheld for COVID: Lifesaving and Free, but Still Few Takers

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The drug is an available, highly effective preventive for millions of immunocompromised people, yet many patients – and even some doctors – are unaware of it, or able to get it. source https://www.webmd.com/lung/news/20220801/evusheld-for-covid-lifesaving-and-free-but-still-few-takers?src=RSS_PUBLIC

T-cells more important in the fight against the COVID-19 virus than initially thought

A COVID-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies is shown to provide good protection in a mouse model, Leiden University Medical Center (LUMC) researchers report in Nature Communications. According to them, the alternative vaccine may offer a solution for people with a weakened immune system, since these individuals don't respond as well to the current ones available. source https://medicalxpress.com/news/2022-08-t-cells-important-covid-virus-thought.html

Technology that responds sensitively to people

How does work affect our daily lives and how does it affect our mental and physical health? How do technical solutions change people and how can devices be made more human-centric? A five-person team at the Fraunhofer Institute for Industrial Engineering IAO is investigating these issues. In the NeuroLab, a laboratory for neuroergonomics, scientists are researching concepts and methods for developing intelligent interfaces between technology and humans. source https://medicalxpress.com/news/2022-08-technology-sensitively-people.html

Health care priorities vary according to region, income and educational attainment

A study conducted in the UPV/EHU's Department of Public Policy and Economic History reveals that people's preferences with respect to public health services differ between regions, and recommends devolving decisions and management of public health care policies to regional governments. source https://medicalxpress.com/news/2022-08-health-priorities-vary-region-income.html

How to get your kid to eat breakfast before school. And yes, it's OK to have dinner leftovers or a sandwich

The cereal bowl is sitting there getting mushy and gross. You ask your child to eat for the 20th time, but still they sit there, totally unwilling. source https://medicalxpress.com/news/2022-08-kid-breakfast-school-dinner-leftovers.html

Research links red meat intake, gut microbiome, and cardiovascular disease in older adults

Does eating more meat—especially red meat and processed meat—raise the risk of cardiovascular disease, and if so, why? Despite intense study, the impact of animal source foods on atherosclerotic cardiovascular disease (ASCVD) is vigorously debated, and the mechanisms underlying potential effects of animal proteins remain unclear. Understanding the impacts of meat consumption is particularly important in older adults, because they are the most vulnerable to heart disease yet may benefit from intake of protein to offset age-related loss of muscle mass and strength. source https://medicalxpress.com/news/2022-08-links-red-meat-intake-gut.html