Jason Lee

The World Health Organization's European office said Saturday that more monkeypox-related deaths can be expected, following reports of the first fatalities outside Africa, while stressing that severe complications were still rare. source https://medicalxpress.com/news/2022-07-europe-monkeypox-related-deaths.html

Officials in New York City declared a public health emergency due to the spread of the monkeypox virus Saturday, calling the city "the epicenter" of the outbreak. source https://medicalxpress.com/news/2022-07-york-city-declares-monkeypox-health.html

Spain reported Saturday a second death in as many days from monkeypox. These are believed to be the first confirmed fatalities from the disease in Europe since its recent spread beyond Africa. source https://medicalxpress.com/news/2022-07-spain-2nd-death-monkeypox.html

Around five percent of people who have had COVID-19 develop long-lasting problems with their sense of smell or taste, a large study said Thursday, potentially contributing to the burden of long COVID. source https://medicalxpress.com/news/2022-07-long-lasting-loss-covid-cases.html

A new drug touted as the first real breakthrough in acne treatment in decades has been available for months in the United States, but when it will hit the shelves in Europe and elsewhere remains unclear. source https://medicalxpress.com/news/2022-07-acne-treatment-europe.html

Spain and Brazil reported their first monkeypox-related deaths on Friday, marking what are thought to be the first fatalities linked to the current outbreak outside of Africa. source https://medicalxpress.com/news/2022-07-spain-brazil-monkeypox-related-deaths-africa.html

Moves by rich countries to buy large quantities of monkeypox vaccine, while declining to share doses with Africa, could leave millions of people unprotected against a more dangerous version of the disease and risk continued spillovers of the virus into humans, public health officials are warning. source https://medicalxpress.com/news/2022-07-monkeypox-vaccines-experts-covid.html

Nosebleeds, also known as epistaxis, are one of the most frequent otolaryngologic (ENT) emergencies worldwide. It is estimated that 60% of the world's population will experience an episode of epistaxis at least once in their lifetime, although only 6–10% of them will seek medical attention. There are several methods for treating epistaxis and one of the most popular ones with a high success rate is nasal packing. However, the choice of the most appropriate nasal plug is vital to the outcome of the treatment. The ideal nasal plug should promote hemostasis—the set of biological mechanisms to stop hemorrhagic processes– and be comfortable for the patient, thus reducing damage to the nasal mucosa. source https://medicalxpress.com/news/2022-07-eco-friendly-nosebleeds.html

Research into the "green whistle" pain relief inhaler has found no obvious harm for pregnant women or their newborn babies in a study looking at ambulance cases over 17 years. source https://medicalxpress.com/news/2022-07-green-pain-relief-inhaler-ambulance.html

While infants exposed to opioids during their mother's pregnancy have been linked to adverse health outcomes, a new study at the University of Missouri has found prenatal opioid exposure could trigger long-term neurological or behavioral effects later in a child's life. source https://medicalxpress.com/news/2022-07-prenatal-opioid-exposure-trigger-neurological.html

The Philippines has detected its first case of monkeypox in a person with a history of overseas travel, officials said Friday. source https://medicalxpress.com/news/2022-07-philippines-case-monkeypox.html

The mayor of San Francisco announced a state of emergency Thursday over the growing number of monkeypox cases, allowing officials to cut through red tape and fight a public health crisis reminiscent of the AIDS epidemic that began devastating the city in the 1980s. source https://medicalxpress.com/news/2022-07-san-francisco-declares-emergency-monkeypox.html

Los Angeles County dropped a plan to impose a universal indoor mask mandate this week as COVID-19 infections and rates of hospitalizations have stabilized, a top health official said Thursday. source https://medicalxpress.com/news/2022-07-los-angeles-county-mask-covid.html

Treatment outcomes were similar between Black and non-Black patients with triple-negative breast cancer who received neoadjuvant durvalumab (Imfinzi) plus chemotherapy, according to phase I/II clinical trial results published in Clinical Cancer Research. source https://medicalxpress.com/news/2022-07-benefits-pre-surgical-immunotherapy-independent-patients.html

Though we often undervalue our ability to smell compared to our abilities to see and hear, our olfactory sense provides our brain with critical information, from detecting potential dangers like smoke to recognizing the sweet smell of baking cookies. source https://medicalxpress.com/news/2022-07-rapid-loss-dementia-smaller-brain.html

In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively. This finding could explain why some people fall ill so much more severely than others. A study led by the University of Bonn (Germany) at least points in this direction. The results have now been published in the journal Nature. They also give hope for new therapies. source https://medicalxpress.com/news/2022-07-covid-energy-flagging-immune-cells.html

A team of scientists led by Professor Dr. Yvonne Mast, head of the Department of Bioresources for Bioeconomy and Health Research at the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures in Braunschweig, Lower Saxony, has developed a new screening strategy for active medical substances. This strategy is based exclusively on analyzing genome sequence data. source https://medicalxpress.com/news/2022-07-screening-method-medical-agents-based.html

An advanced form of cardiac MRI, developed by academics at UCL in collaboration with the Royal Free Hospital, has for the first-time enabled clinicians to measure the effectiveness of chemotherapy in patients with the life-limiting condition 'stiff heart syndrome'. source https://medicalxpress.com/news/2022-07-advanced-mri-benefits-patients-heart.html

A needle-free vaccine patch could better fight COVID-19 variants, such as Omicron and Delta, than a traditional needle vaccine according to a University of Queensland study in mice. source https://medicalxpress.com/news/2022-07-covid-vaccine-patch-variants-needles.html

A recent surge in factitious disorder has taken place online, and it appears to be due largely to TikTok. source https://www.webmd.com/mental-health/features/dying-attention-faking-illness-becomes-online-epidemic?src=RSS_PUBLIC

If you compare the brain of someone who has died from neurodegenerative disease to that of a healthy person, you can't miss the difference: In the case of severe Alzheimer's, the brain will be noticeably smaller, with large gaps where pieces would normally nestle close together. source https://medicalxpress.com/news/2022-07-cell-scientists-high-resolution-brain-alzheimer.html

For people with opioid addiction, many hurdles stand in the way of getting effective treatment—and COVID-19 could have made it harder. source https://medicalxpress.com/news/2022-07-telehealth-video-lifeline-veterans-opioid.html

Researchers have taken an important step toward understanding the microscopic battle that plays out between our lung cells and the SARS-CoV-2 virus that causes COVID-19. A UC Berkeley-led study has identified specific proteins within our bodies that can promote or protect us from SARS-CoV-2 infections, potentially opening the door to new antiviral therapies. source https://medicalxpress.com/news/2022-07-human-lung-proteins-advance-thwart.html

Getting children closer to green spaces as they grow up could improve their lung health, according to a study published today in the European Respiratory Journal. source https://medicalxpress.com/news/2022-07-children-closer-nature-lung-health.html

Preliminary evidence shows potential for a fully-automated, online behavioral obesity treatment program to serve as a pragmatic resource in the primary care setting, according to a new study in Obesity journal. source https://medicalxpress.com/news/2022-07-online-automated-obesity-treatment-weight-loss.html

High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in Obesity journal. source https://medicalxpress.com/news/2022-07-aldose-reductase-diet-induced-obesity.html

Hormone therapy for prostate cancer increases the risk of cardiovascular disease-related death especially in older men, according to a population study involving more than 13,000 patients. source https://medicalxpress.com/news/2022-07-hormone-therapy-prostate-cancer-dying.html

Better diagnosis and treatment of the incurable eye disease age-related macular degeneration is a step closer, thanks to the discovery of new genetic signatures of the disease. source https://medicalxpress.com/news/2022-07-genetic-clues-age-related-macular-degeneration.html

British researchers reported a breakthrough Monday in mysterious hepatitis cases affecting young children, finding the serious liver condition was linked to co-infection of two common viruses, but not the coronavirus. source https://medicalxpress.com/news/2022-07-breakthrough-mystery-child-hepatitis.html

Average life expectancy in Germany dropped noticeably between 2019 and 2021, the national statistics office said Tuesday, a change that it attributed to unusually high numbers of deaths during the coronavirus pandemic. source https://medicalxpress.com/news/2022-07-german-life-decreased-pandemic-years.html

A cohort study of persons with incident atrial fibrillation (AF) has found that AF after noncardiac surgery is common and comprises 13 percent of all new AF diagnoses. Postoperative AF is also associated with similar risk for stroke or transient ischemic attack (TIA) and death as AF unrelated to surgery. The findings are published in Annals of Internal Medicine. source https://medicalxpress.com/news/2022-07-atrial-fibrillation-non-cardiac-surgery-common.html

A new position paper from the American College of Physicians (ACP) offers guidance regarding ethical decision-making for the integration of precision medicine and genetic testing into internal medicine. ACP's advice is published in Annals of Internal Medicine. source https://medicalxpress.com/news/2022-07-acp-guidance-ethical-genetic-precision.html

Medical education, research and clinical guidelines are all available to support the initiation of gender-affirming care for transgender people, but a York University-led qualitative study has found these resources are sparse when patients discontinue or reverse gender-affirming medical or surgical interventions—referred to as detransition. source https://medicalxpress.com/news/2022-07-detransition-medical.html

The antiviral drugs molnupiravir and nirmatrelvir–ritonavir (Paxlovid), when used to treat nonsevere COVID-19, most likely reduce the risk of subsequent progression to hospitalization and death, according to new research published in CMAJ (Canadian Medical Association Journal). source https://medicalxpress.com/news/2022-07-antivirals-nonsevere-covid-hospitalizations-deaths.html

Prime Minister Jacinda Ardern warned an outbreak of foot-and-mouth disease in Indonesia could cost thousands of New Zealand jobs, as her nation and neighbouring Australia stepped up border biosecurity restrictions. source https://medicalxpress.com/news/2022-07-indonesia-foot-mouth-outbreak-prompts.html

As a medical student in North Korea, Lee Gwang-jin said he treated his fevers and other minor ailments with traditional herbal medicine. But bad illness could mean trouble because hospitals in his rural hometown lacked the ambulances, beds, even the electricity at times needed to treat critical or emergency patients. source https://medicalxpress.com/news/2022-07-north-korea-traditional-medicine-covid-.html

The World Health Organization on Saturday declared the monkeypox outbreak, which has affected nearly 17,000 people in 74 countries, to be a global health emergency—the highest alarm it can sound. source https://medicalxpress.com/news/2022-07-triggers-highest-monkeypox.html

The White House said Sunday it was confident authorities could "eliminate" monkeypox from the United States by speeding up the rollout of vaccinations and treatment to combat the virus's spread. source https://medicalxpress.com/news/2022-07-monkeypox-outbreak-white-house.html

Air-conditioned shops in France will be ordered to keep their doors closed or risk being fined, a minister said Sunday announcing an upcoming rule to combat energy wastage. source https://medicalxpress.com/news/2022-07-france-air-conditioned-doors.html

Avian influenza viruses, or "bird flu," normally infects, well, birds. But when the virus does infect humans, it can cause more severe illness than other similar influenza viruses. source https://medicalxpress.com/news/2022-07-flu-viruses-severe-infections.html

Right now, more than 1 in 10 Americans take medicines for depression—a number that has risen during the pandemic. source https://medicalxpress.com/news/2022-07-science-depression-patients-today.html

Two children have been diagnosed with monkeypox in the U.S., health officials said Friday. source https://medicalxpress.com/news/2022-07-children-monkeypox.html

While African Americans have disproportionately higher COVID-19 infection and mortality rates compared to white individuals, they also have disproportionately lower COVID-19 vaccination rates, which is partially fueled by vaccine hesitancy. source https://medicalxpress.com/news/2022-07-historical-mistrust-health-industry-contributes.html

New research led by scientists at Arizona State University has revealed some of the first detailed molecular clues associated with one of the leading causes of death and disability, a condition known as traumatic brain injury (TBI). source https://medicalxpress.com/news/2022-07-scientists-molecular-clues-acute-chronic.html

Physician-scientists at the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute have discovered that a gene called FOXR2 that is normally turned off in most tissues in the body is activated in at least 70% of cancer types and 8% of all individual tumors. source https://medicalxpress.com/news/2022-07-scientists-key-gene-cancer.html

Countries meeting to negotiate a new international accord on how to handle future pandemics agreed Thursday that it should be legally binding, the World Health Organization said. source https://medicalxpress.com/news/2022-07-countries-pandemic-accord-legally.html

The spread of monkeypox in the U.S. could represent the dawn of a new sexually transmitted disease, though some health officials say the virus that causes pimple-like bumps might yet be contained before it gets firmly established. source https://medicalxpress.com/news/2022-07-monkeypox-virus-entrenched-std.html

President Joe Biden tested positive for COVID-19 on Thursday, is experiencing mild symptoms and has begun taking Paxlovid, an antiviral pill treatment. source https://medicalxpress.com/news/2022-07-biden-covid-.html

The way in which a patient is told they have serious eye disease can impact their psychological health and ability to cope with their condition in the long-term, according to new research published in the open-access journal BMJ Open. source https://medicalxpress.com/news/2022-07-trauma-diagnosis-eye-disease-patients.html

A world-first study by Monash University, in Melbourne, Australia has discovered a pathway to the regeneration of insulin in pancreatic stem cells, a major breakthrough toward new therapies to treat Type 1 and Type 2 diabetes. source https://medicalxpress.com/news/2022-07-pathway-regeneration-insulin-major-breakthrough.html

We often hear the phrase 'growing pains' used by the general public to describe muscle or joint pain in young people and the term is also used by health professionals. However researchers have found there is no consistent medical definition of the condition behind a diagnosis. source https://medicalxpress.com/news/2022-07-medical-definition-pains.html

The World Health Organization's expert monkeypox committee will meet on Thursday to decide whether to deploy the UN health agency's rarely used top alert for the worsening virus outbreak. source https://medicalxpress.com/news/2022-07-monkeypox-emergency-declared.html

When the US Supreme Court overturned the nationwide right to abortion, Julie Crowe went straight online to do some shopping. She ordered 10 packs of the emergency contraceptive pill known as Plan B for immediate delivery. source https://medicalxpress.com/news/2022-07-alarm-bells-abortion-fuels-morning-after.html

Thousands of cattle are covered in blisters from highly infectious foot-and-mouth disease in Indonesia, sounding the alarm for the country, its Southeast Asian neighbors and Australia. The virus found in two provinces in May has now infected several hundred-thousand animals across multiple provinces, including the popular tourist destination of Bali. source https://medicalxpress.com/news/2022-07-foot-and-mouth-disease-efforts.html

Heated tobacco products have soared in popularity as a "smoke free" alternative to cigarettes in recent years, but a peer-reviewed report has suggested their emissions could be considered smoke—a claim strongly rejected by the tobacco industry. source https://medicalxpress.com/news/2022-07-tobacco-products.html

Having emergency services work together to attend mental health emergencies reduces the likelihood of the person in crisis ending up in hospital, a study from the University of Otago in New Zealand has found. source https://medicalxpress.com/news/2022-07-outcomes-police-ambulance-mental-health.html

Protection against severe COVID-19 by two doses of Pfizer-BioNTech and AstraZeneca COVID-19 vaccines remained high up to six months after second doses, finds new research which analysed NHS health record data on over seven million adults. Reassuringly, the University of Bristol-led study published in The BMJ today, found protection in older adults aged over 65 years, and in clinically vulnerable adults. source https://medicalxpress.com/news/2022-07-pfizer-biontech-astrazeneca-vaccines-high-severe.html

Telling a child about their mother's risk of hereditary breast and ovarian cancer does not adversely influence the offspring's lifestyle or quality of life in the long term, according to a new study led by researchers at Georgetown Lombardi Comprehensive Cancer Center. source https://medicalxpress.com/news/2022-07-children-mother-genetic-cancer-impact.html

Scientific advancements have often been held back by the need for high volumes of data, which can be costly, time-consuming, and sometimes difficult to collect. But there may be a solution to this problem when investigating how our bodies fight illness: a new machine-learning method called MotifBoost. This approach can help interpret data from T-cell receptors (TCRs) in identifying past infections to specific pathogens. By focusing on a collection of short sequences of amino acids in the TCRs, a research team achieved more accurate results with smaller datasets. This work may shed light on the way the human immune system recognizes germs, which may lead to improved health outcomes. source https://medicalxpress.com/news/2022-07-infection-machine-methods.html

Rutgers scientists have found more clear-cut evidence of how the destructive proteins linked to Alzheimer's disease attack human brain cells and destroy surrounding tissue. source https://medicalxpress.com/news/2022-07-scientists-reveal-evidence-key-mechanism.html

The tiny Pacific state of Micronesia has lost its status as one of the few Covid-free countries, after confirming community cases on two islands. source https://medicalxpress.com/news/2022-07-micronesia-covid-free-status-outbreak.html

The head of the Food and Drug Administration has asked for a review of the agency's food and tobacco programs following months of criticism over their handling of the baby formula shortage and e-cigarette reviews. source https://medicalxpress.com/news/2022-07-fda-oversight-formula-juul.html

After decades of study, there remains no clear evidence that serotonin levels or serotonin activity are responsible for depression, according to a major review of prior research led by UCL scientists. source https://medicalxpress.com/news/2022-07-evidence-depression-serotonin-comprehensive.html

British primary and secondary schoolchildren are getting the majority of their lunchtime calories from 'ultra-processed' foods, according to a study led by researchers at Imperial College London and published today in the journal Nutrients. source https://medicalxpress.com/news/2022-07-ultra-processed-foods-two-thirds-britain-school.html

A new paper in the Journal of the National Cancer Institute, published by Oxford University Press, finds that menopausal hormone therapy for breast cancer survivors is not associated with breast cancer reoccurrence, despite worries among some researchers and physicians. source https://medicalxpress.com/news/2022-07-hormone-therapy-doesnt-breast-cancer.html

Over several decades, neuroscientists have created a well-defined map of the brain's "language network," or the regions of the brain that are specialized for processing language. Found primarily in the left hemisphere, this network includes regions within Broca's area, as well as in other parts of the frontal and temporal lobes. source https://medicalxpress.com/news/2022-07-similar-patterns-brain-language-speakers.html

Freddy Fernandez almost wasn't here, on his couch in his Missouri home, his baby on his lap, gnawing on the pulse oximeter that he uses to check his oxygen levels after a months-long bout with COVID-19. source https://medicalxpress.com/news/2022-07-scars-covid-persist-sickest-survivors.html

A team of experts encouraged ongoing investigation of the benefits of exercise training for individuals with multiple sclerosis, citing shortcomings of available studies. They outlined their outlook for this avenue of research in, "Exercise in multiple sclerosis," published in The Lancet Neurology. source https://medicalxpress.com/news/2022-07-scientists-advocate-benefits-multiple-sclerosis.html

Scientists at the University of Reading measured the impact of high doses of Vitamin B6 on young adults and found that they reported feeling less anxious and depressed after taking the supplements every day for a month. source https://medicalxpress.com/news/2022-07-vitamin-b6-supplements-anxiety-depression.html

In one of the first studies of its kind, Mayo Clinic researchers have analyzed a large group of patients to understand their motivations for seeking stem cell therapies and whether expectations are grounded in science. The findings could help health care professionals cut through misleading claims and better counsel patients. The research by Jennifer Arthurs; Zubin Master, Ph.D.; and Shane Shapiro, M.D., is published in npj Regenerative Medicine. source https://medicalxpress.com/news/2022-07-survey-patients-stem-cell-treatments.html

States that legalized recreational marijuana saw a subsequent increase in traffic crashes and fatalities, according to new research in the Journal of Studies on Alcohol and Drugs. source https://medicalxpress.com/news/2022-07-legalization-marijuana-linked-traffic-fatalities.html

Why is it that someone who hasn't ridden a bicycle in decades can likely jump on and ride away without a wobble, but could probably not recall more than a name or two from their 3rd grade class? source https://medicalxpress.com/news/2022-07-memory-formation-real.html

On a hot Sunday afternoon in New York, the epicenter of the US monkeypox outbreak, a long line of men aged 20 to 40 wait for a vaccine to protect themselves and their loved ones against the virus. source https://medicalxpress.com/news/2022-07-lines-york-monkeypox-vaccine.html

Two cases of the deadly Marburg virus have been identified in Ghana, the first time the Ebola-like disease has been found in the West African nation, health authorities announced Sunday. source https://medicalxpress.com/news/2022-07-ghana-cases-deadly-marburg-virus.html

The use of precise, accurate language in defining Black communities in health care research must improve in Canada, or there is a risk that health research will fail to meet the needs of Black people in Canada, argues a University of Ottawa professor in a commentary published in CMAJ (Canadian Medical Association Journal). source https://medicalxpress.com/news/2022-07-black-canadian-health.html

Roadblocks to accessing data on vaccine effectiveness from provincial health ministries impede researchers' ability to inform a national pandemic response and maintain public trust, according to an analysis in CMAJ (Canadian Medical Association Journal). source https://medicalxpress.com/news/2022-07-access-provincial-sars-cov-vaccination-canada.html

In some homes, summer may mean more screen time for kids. And among concerns that come with children spending more hours on digital devices, video games and televisions—and less time outdoors—harm to their eyes. source https://medicalxpress.com/news/2022-07-parents-screen-impact-children-eye.html

Summer is a great time to enjoy the outdoors with your dog, but when the temperatures spike or the fireworks come out, it's time to make sure your furry best friend is having just as good a time as you are. source https://medicalxpress.com/news/2022-07-panting-pooches-summer-dog.html

Temperatures are skyrocketing across the United States, as the high sky sun bakes everyone who ventures out for some summer fun. source https://medicalxpress.com/news/2022-07-safe-summer-sizzle.html

A comparison of matched patient cases involving ACL repair with ACL reconstruction found that patients who undergo ACL repair have better outcomes than those who have ACL reconstruction, according to research presented today at the American Orthopaedic Society of Sports Medicine 2022 Annual Meeting. source https://medicalxpress.com/news/2022-07-acl-patients-outcomes-reconstruction.html

Patients undergoing a Bankart repair with remplissage have a better rate of survival than those with an isolated Bankart repair, according to research presented today at the American Orthopaedic Society of Sports Medicine 2022 Annual Meeting. source https://medicalxpress.com/news/2022-07-remplissage-postoperative-recurrent-instability-bankart.html

More than 100,000 monkeypox vaccine doses are being sent to states in the next few days, and several million more are on order in the months ahead, U.S. health officials said Friday. source https://medicalxpress.com/news/2022-07-states-monkeypox-vaccine.html

China on Saturday reported its highest number of coronavirus cases since May, with millions in lockdown this weekend as authorities persist with their zero-Covid policy. source https://medicalxpress.com/news/2022-07-china-covid-outbreak-millions-lockdown.html

A new study by Portland State University's Robert Strongin doctoral student Kaelas Munger provides insight into the potential risks of vaping cannabinoid acetates. They found that the toxic gas known as ketene is released when cannabinoid acetates are heated under vaping conditions. Ketene was found previously by researchers studying vitamin E acetate in 2019 in the emissions from a commercial e-cigarette. This led to ketene's identification as a possible source of the vaping-induced lung injury outbreak that led to nearly 3,000 hospitalizations and deaths in the U.S. as of February 2020. While ketene is known to be toxic to humans, Strongin said it's too dangerous to study in order to fully understand its impact on the human body. source https://medicalxpress.com/news/2022-07-vaping-cannabinoid-acetate-formation-deadly.html

In one of the first investigations of the effectiveness of a second mRNA booster against COVID-19 Omicron variants, a study from the U.S. Centers for Disease Control and Prevention (CDC) has found that a second booster shot significantly improved effectiveness against widespread variants Omicron BA.1 and BA.2/BA.2.12.1. source https://medicalxpress.com/news/2022-07-mrna-booster-significantly-effective-omicron.html

Since COVID-19 vaccines first became available to protect against infection and severe illness, there has been much uncertainty about how long the protection lasts, and when it might be necessary for individuals to get an additional booster shot. source https://medicalxpress.com/news/2022-07-vaccine-covid-short-lived-booster-shots.html

Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma. Although new immunotherapies are effective in some patients with melanoma brain metastases, little is known about the reasons for melanoma's spread to the brain and the lower response rates to many therapies. source https://medicalxpress.com/news/2022-07-insights-melanoma-brain-metastases.html

A commonly used behavioral intervention—informing primary care physicians about how their performance compares to that of their peers—has no statistically significant impact on preventive care performance. It does, however, decrease physicians' job satisfaction while increasing burnout. source https://medicalxpress.com/news/2022-07-physicians-peers-decreases-job-satisfaction.html

A scientific team from MedUni Vienna's Center for Brain Research has now identified specific cells that regulate the transmission of information between brain areas. This discovery forms the basis for the development of new treatment options for neuropsychiatric disorders such as schizophrenia and autism, which are characterized by impaired coordination of information flow in the brain. The study has now been published in Science. source https://medicalxpress.com/news/2022-07-neuronal-cell-brain.html

Innate immunity is activated when the pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs). A research team from Kanazawa University has shown that a liver-derived secretory protein LECT2, a hepatokine, binds to the HGF receptor MET, a proto-oncogene product, to suppress the proliferation signal of MET. LECT2 activates retinoic acid-inducible gene-I, enhancing antiviral and innate immune responses through MET. Thus, LECT2 is an anti-proliferative and immunoregulatory factor that could be a therapeutic target for viral infections and cancer. source https://medicalxpress.com/news/2022-07-elucidation-antiviralinnate-immune-response-mechanism.html

Increased misinformation and the disruption of global supply chains due to COVID are behind the biggest sustained drop in childhood vaccinations in three decades, a UN report said. source https://medicalxpress.com/news/2022-07-red-global-immunization-backslide.html

Pathology Subspecialties - What Sub-specialties and Fellowships are Available for Pathologists? https://www.umhs-sk.org/blog/how-to-become-a-pathologist#pathology_subspecialties The majority of people as well as most physicians do not realize how broad of a field Pathology is. This gives Pathologists a huge choice of how they would like to practice. According to a report from the American Society for Clinical Pathology, ASCP, over 90% of pathology residents plan on attending at least one fellowship while over 40% plan on attending 2 or more fellowship programs. Currently, there are eleven subspecialties that offer board certification and even more non-board certified fellowships available. According to the American Board of Pathology, the subspecialties that have board certification available are: Blood Banking and Transfusion Medicine: 1 year in length. Clinical Chemical Pathology: One to two years in length. Clinical Informatics: Typically two years in length. Cytopathology: One year...

India has reported its first confirmed case of monkeypox after a 35-year-old man with a history of travel to the Middle East showed symptoms, officials said. source https://medicalxpress.com/news/2022-07-india-case-monkeypox.html

About 25 million children worldwide have missed out on routine immunizations against common diseases like diptheria, largely because the coronavirus pandemic disrupted regular health services or triggered misinformation about vaccines, according to the U.N. source https://medicalxpress.com/news/2022-07-million-kids-routine-vaccinations-covid.html

The authors of a ground-breaking University of Otago, Christchurch study are calling for immediate changes to Aotearoa New Zealand's suicide prevention strategy and the Sale and Supply of Alcohol Act, due to figures showing more than 26 percent of all suicide deaths in this country involve acute alcohol use. source https://medicalxpress.com/news/2022-07-acute-alcohol-linked-quarter-zealand.html

Findings from a first-of-its-kind study published today in the American Journal of Infection Control (AJIC) suggest that infection preventionists experienced worsening mental and physical health as a result of stressors related to the COVID-19 pandemic. The study, which evaluated infection preventionists' health, well-being and their association with workplace wellness programs, highlights a need to fix hospital and healthcare facilities' system issues that cause burnout and poor health, and to enhance workplace wellness programs and culture. source https://medicalxpress.com/news/2022-07-covid-pandemic-negatively-impacted-infection.html

In a qualitative, interview-based study of Emergency Department leaders, researchers at the University of Colorado Anschutz Medical Campus found most were motivated to provide high quality pediatric sepsis care but disagreed on how best to do it. source https://medicalxpress.com/news/2022-07-ed-clinical-leaders-eager-early.html

Lung cancer is the deadliest form of cancer, accounting for an estimated 1.8 million deaths worldwide. source https://medicalxpress.com/news/2022-07-genetic-discovery-lung-cancer-treatment.html

A major public health concern, traumatic brain injury is the leading cause of death and disability in children 0-4 and 15-19 years of age. With 308,000 average annual cases in the United States, such accidents have become frequent among school-aged children participating in sports and playground activities that involve equipment (e.g., bicycling, football, basketball, and soccer). source https://medicalxpress.com/news/2022-07-consumer-product-related-traumatic-brain-injury.html

Even low levels of lead exposure can lower cognitive performance, cause learning difficulties, and prompt behavior issues. And we’ve stopped testing for it. source https://www.webmd.com/children/features/lead-exposure-children?src=RSS_PUBLIC

New research from a collaborative team at Cleveland Clinic, led by Timothy Chan, MD, Ph.D., Chair of the Center for Immunotherapy and Precision Immuno-Oncology in the Lerner Research Institute, is demonstrating that pathogenic Polymerase epsilon and delta (POLE/POLD1) genetic mutations lead to improved response to immune checkpoint blockade (ICB), a growing class of immunotherapy drugs. source https://medicalxpress.com/news/2022-07-tumors-specific-genetic-mutations-response.html

To put the COVID-19 pandemic in the rearview mirror and prevent other coronaviruses from causing havoc, the world needs an arsenal of measures to prevent and treat these infections. To develop new medications, researchers are working to target one protein, nsp13, that these viruses need to replicate. In a study in ACS Infectious Diseases, one team describes a new approach to identifying molecules that interfere with this protein, a step toward development of pan-coronavirus antivirals. source https://medicalxpress.com/news/2022-07-covid-antiviral.html

Researchers have developed a noninvasive method to identify a potential cause of hypertension with a drastic reduction in radiation exposure, a study shows. source https://medicalxpress.com/news/2022-07-agent-root-hypertension-causing-tumor.html

Black children who underwent heart transplant surgery for the first time were more than three times as likely to die after six months than white children, according to new research published today in the Journal of the American Heart Association. source https://medicalxpress.com/news/2022-07-disparity-black-children-heart-transplant.html

Health officials in South Korea are expanding booster shots to adults 50 and over as COVID-19 cases creep up again across the country. source https://medicalxpress.com/news/2022-07-korea-booster-shots-covid-cases.html

Physicians and researchers are urging New Mexico legislators to allow the use of psychedelic mushrooms in mental health therapy aimed at overcoming depression, anxiety, psychological trauma and alcoholism. source https://medicalxpress.com/news/2022-07-doctors-urge-access-psychedelic-therapies.html

Researchers are one step closer to understanding the "internal GPS" of animals and humans, by investigating whether rats can learn spaces just by observation. In a new study published in Frontiers in Behavioral Neuroscience, the researchers show that rats do not need to physically explore an environment to learn about a specific location; simply observing another rat is sufficient. source https://medicalxpress.com/news/2022-07-rats-friends-internal-gps.html

Among people who received endovascular therapy to mechanically remove a clot in their large brain artery, those who had a rare genetic variant found primarily in people of East Asian descent (Japanese, Chinese and Korean) were more likely to have the vessel reclog during or shortly after the procedure, according to a small study published today in Stroke: Vascular and Interventional Neurology. source https://medicalxpress.com/news/2022-07-people-east-asian-descent-vessels.html

Researchers have uncovered how post-viral fatigue syndromes, including Long COVID, become life-changing diseases and why patients suffer frequent relapses. source https://medicalxpress.com/news/2022-07-insight-covid.html

As many as 10,000 Australians are predicted to develop lung cancer in their lifetime from being exposed to silica dust, new Curtin University modeling has found amid warnings more than half a million Australian workers are currently exposed to the harmful dust. source https://medicalxpress.com/news/2022-07-aussie-workers-lung-cancer-silica.html

Russia on Tuesday said it had detected the first case of monkeypox in the country in a man who returned from a trip to several European nations. source https://medicalxpress.com/news/2022-07-russia-case-monkeypox.html

Offering intensive, weekly telephone-based cessation counseling along with nicotine replacement for people who smoke and who were undergoing screening for lung cancer resulted in over a two-fold greater cigarette quit rate compared to people who received minimal counseling and nicotine replacement, according to results of a national, randomized trial conducted by investigators at Georgetown Lombardi Comprehensive Cancer Center and colleagues. source https://medicalxpress.com/news/2022-07-intensive-telephone-based-cessation-results.html

A new study from Carnegie Mellon University found that drinking alone during adolescence and young adulthood strongly increases risk for alcohol use disorder (AUD) later in life. This risk is especially high for women. The results are available in the July issue of the journal Drug and Alcohol Dependence. source https://medicalxpress.com/news/2022-07-foreshadows-future-alcohol-problems.html

The quickly changing coronavirus has spawned yet another super contagious omicron mutant that's worrying scientists as it gains ground in India and pops up in numerous other countries, including the United States. source https://medicalxpress.com/news/2022-07-coronavirus-mutant-india.html

People with hematologic malignancies—or blood cancers including leukemia, lymphoma, and multiple myeloma—have an impaired immune system due to their disease and its treatment, putting them at risk of severe COVID-19 infection and experiencing a reduced response to COVID-19 vaccination. In a recent study published by Wiley online in Cancer, a peer-reviewed journal of the American Cancer Society, less than half of patients with hematologic malignancies mounted detectable antibodies after initial COVID-19 vaccination, but 56% of "nonresponders" produced antibodies after receiving a booster dose. source https://medicalxpress.com/news/2022-07-adults-blood-cancers-booster-dose.html

For health care providers who may be caring for Ukrainians displaced by the war, a new analysis published in CMAJ (Canadian Medical Association Journal) provides an overview of health and clinical considerations in this population. It also highlights the key gaps in the Canadian health care systems that need to be addressed to deliver equitable care to refugees and other migrants. source https://medicalxpress.com/news/2022-07-ukraine-war-refugee-health.html

Speaking the same language as their physician can make for healthier patients, new research using ICES data confirms. Frail, older patients admitted to hospital who received care from physicians who spoke their primary language had shorter hospital stays, fewer falls and infections, and were less likely to die in hospital, according to a new study published in CMAJ (Canadian Medical Association Journal). source https://medicalxpress.com/news/2022-07-quality-safety-hospital-physicians-patients.html

The Chinese capital Beijing appears to have backed off a plan to launch a vaccine mandate for entry into certain public spaces after pushback from residents. source https://medicalxpress.com/news/2022-07-beijing-retract-vaccine-mandate-pushback.html