Commonly mutated gene shown to drive therapeutic resistance in HER2-positive breast cancer

PIK3CA is a gene that makes an enzyme called PI3K, which is involved in many important cell functions. When PIK3CA mutates, however, it can make the PI3K enzyme become overactive and cause cancer cells to grow.

source https://medicalxpress.com/news/2022-07-commonly-mutated-gene-shown-therapeutic.html