Organ-on-a-chip study reveals mechanism of SARS-CoV-2 invasion into blood vessels

A research group led by CiRA Junior Associate Professor Kazuo Takayama and Associate Professor Yoshiaki Okada of Osaka University has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression of Claudin-5 (CLDN5) to invade the blood vessels.

source https://medicalxpress.com/news/2022-09-organ-on-a-chip-reveals-mechanism-sars-cov-invasion.html