Hydrocephalus often caused by disrupted brain development

Hydrocephalus in children often has completely different causes than previously assumed. This is the conclusion of an international study. The researchers identified a series of mutations that cause disruption of early brain development. The characteristic enlargements of the fluid-filled cavities in the brain are a consequence of this. The study was led by Yale, Harvard and Bonn Universities; its findings also have implications for the diagnosis and treatment of this serious condition. The results are published in the journal Nature Neuroscience.

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