Uncovering the HIV life cycle

Though it has been eclipsed lately by SARS-CoV-2, there is another global epidemic still threatening people: HIV/AIDS. According to UNAIDS, a United Nations initiative, some 38 million people worldwide are currently infected with HIV. Almost as many have died as a result of AIDS since the outbreak of the HIV pandemic in the 1980s. In the search for new approaches to antiviral therapies, scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the Robert Koch Institute (RKI) in Berlin have now developed a new technology that can be used to analyze and impact key stages of the HIV life cycle. Their findings were published today in the journal Nature Structural & Molecular Biology.

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