Safety and effectiveness of medications in relation to kidney function

Kidney function plays an important role in drug safety and effectiveness. As many medications are excreted by the kidneys, patients with reduced kidney function are at a higher risk of toxic drug levels. Chronic kidney disease (CKD) has been recognized as a leading public health problem worldwide with a global estimated prevalence over 9 percent.

source https://medicalxpress.com/news/2021-12-safety-effectiveness-medications-kidney-function.html