An estrogen receptor that promotes cancer also causes drug resistance

Cancer cells proliferate despite a myriad of stresses—from oxygen deprivation to chemotherapy—that would kill any ordinary cell. Now, researchers at UC San Francisco have gained insight into how they may be doing this through the downstream activity of a powerful estrogen receptor. The discovery offers clues to overcoming resistance to therapies like tamoxifen that are used in many types of breast cancer.

source https://medicalxpress.com/news/2021-09-estrogen-receptor-cancer-drug-resistance.html