Brain organoids mimic head size changes associated with type of autism

Variations in the 16p11.2 region of the genome are associated with autism spectrum disorder. While people with genetic deletions in this region have larger heads (macrocephaly) and people with genetic duplications have smaller heads (microcephaly), both variation types affect brain development and function.

source https://medicalxpress.com/news/2021-08-brain-organoids-mimic-size-autism.html